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View article: Anesthetic management for open reduction and internal fixation of the mandibular fracture in a patient with congenital pulmonary hypoplasia: a case report
Anesthetic management for open reduction and internal fixation of the mandibular fracture in a patient with congenital pulmonary hypoplasia: a case report Open
This case demonstrates that adults with asymptomatic CPH can safely undergo general anesthesia when a meticulous, multidisciplinary pathway is followed. Individualized lung-protective ventilation strategy, restrictive fluid management, and…
View article: GMAFNet: Gated Mechanism Adaptive Fusion Network for 3D Semantic Segmentation of LiDAR Point Clouds
GMAFNet: Gated Mechanism Adaptive Fusion Network for 3D Semantic Segmentation of LiDAR Point Clouds Open
Three-dimensional semantic segmentation plays a crucial role in advancing scene understanding in fields such as autonomous driving, drones, and robotic applications. Existing studies usually improve prediction accuracy by fusing data from …
View article: Zinc oxide nanoparticle chelated phosphocreatine-grafted chitosan composite hydrogels for enhancing osteogenesis and angiogenesis in bone regeneration
Zinc oxide nanoparticle chelated phosphocreatine-grafted chitosan composite hydrogels for enhancing osteogenesis and angiogenesis in bone regeneration Open
Introduction The natural polysaccharide-based injectable hydrogels have showed significant interest to use as 3D scaffolds for critical-sized bone defect repair. Methods Here, we incorporated ZnO nanoparticles (NPs) into a newly synthesize…
View article: Determination and pharmacokinetic study of thyroid hormone receptor-β agonist resmetirom in beagle dogs using HPLC-MS/MS method
Determination and pharmacokinetic study of thyroid hormone receptor-β agonist resmetirom in beagle dogs using HPLC-MS/MS method Open
A HPLC-MS/MS method for determination of thyroid hormone receptor-β agonist resmetirom was established and validated, and pharmacokinetic study was conducted in beagle dogs after oral administration. Methanol-0.1 % formic acid was used as …
View article: Complement C5aR blockade attenuates LPS-induced acute kidney injury by regulating ferroptosis via nuclear factor-erythroid 2-related factor 2 signaling in mice
Complement C5aR blockade attenuates LPS-induced acute kidney injury by regulating ferroptosis via nuclear factor-erythroid 2-related factor 2 signaling in mice Open
Acute kidney injury (AKI) is a prevalent and severe condition characterized by sudden renal dysfunction. In this investigation, we explored the therapeutic potential of C5a receptor (C5aR) blockade in a murine model of lipopolysaccharide (…
View article: Exploration of mortality-associated creatinine thresholds for acute kidney injury in cardiac surgery patients with impaired kidney function: a single-center retrospective cohort study
Exploration of mortality-associated creatinine thresholds for acute kidney injury in cardiac surgery patients with impaired kidney function: a single-center retrospective cohort study Open
This study proposes new SCr thresholds specific to cardiac surgery patients with impaired kidney function. If externally validated, these thresholds may aid in improving risk stratification and guiding perioperative management. Nonetheless…
View article: Association Between the Preoperative Triglyceride–Glucose Index and Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Cardiac Surgery
Association Between the Preoperative Triglyceride–Glucose Index and Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Cardiac Surgery Open
Background: Acute kidney injury (AKI) is a major complication of cardiac surgery, particularly in patients with pre-existing chronic kidney disease (CKD), who are at higher risk due to their compromised renal function. This study investiga…
View article: NRF1 coordinates mitochondrial adaptations to dampen intracellular ROS and inflammatory responses during ischemia reperfusion
NRF1 coordinates mitochondrial adaptations to dampen intracellular ROS and inflammatory responses during ischemia reperfusion Open
Ischemia reperfusion injury (IRI) is commonly seen in surgical procedures involving cardiopulmonary bypass and post-shock reperfusion. Sudden restoration of blood flow after a period of ischemia triggers a rapid accumulation of reactive ox…
View article: Nafamostat mesylate augments survival in rats afflicted by exertional heat stroke
Nafamostat mesylate augments survival in rats afflicted by exertional heat stroke Open
Objective To evaluate the impact of Nafamostat mesylate (NM) in improving survival outcomes among rats subjected to exertional heat stroke. Methods This study involved a cohort of 45 specific pathogen-free (SPF) male Sprague Dawley (SD) ra…
View article: A higher preoperative total protein to albumin ratio independently predicted more severe postoperative acute kidney injury in patients with acute type A aortic dissection: a retrospective cohort study of 224 cases
A higher preoperative total protein to albumin ratio independently predicted more severe postoperative acute kidney injury in patients with acute type A aortic dissection: a retrospective cohort study of 224 cases Open
Objectives In this retrospective study, we investigated the incidence of postoperative acute kidney injury (AKI) and determined the predictors associated with AKI in patients underwent surgeries for acute type A aortic dissection (ATAAD). …
View article: Training and Generalization of a Fault Classification AI Model for Lift Door System Using Data Augmentation
Training and Generalization of a Fault Classification AI Model for Lift Door System Using Data Augmentation Open
Data augmentation is an effective method in machine learning to address data scarcity. When the cost of acquiring specific state data in professional fields are high, data augmentation can expand the limited datasets and improve model perf…
View article: Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats
Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats Open
Background Coagulation disorders play a pivotal role in the elevated mortality rates associated with exertional heatstroke (EHS). Purpose To investigate the impact of Shengmai Yin Oral Liquid (SMY) on heatstroke-induced coagulopathy (HIC) …
View article: An Attention‐Aware Multi‐Task Learning Framework Identifies Candidate Targets for Drug Repurposing in Sarcopenia
An Attention‐Aware Multi‐Task Learning Framework Identifies Candidate Targets for Drug Repurposing in Sarcopenia Open
Background Sarcopenia presents a pressing public health concern due to its association with age‐related muscle mass decline, strength loss and reduced physical performance, particularly in the growing older population. Given the absence of…
View article: Association between perioperative platelet distribution width changes and postoperative acute kidney injury in patients with renal insufficiency: a retrospective study
Association between perioperative platelet distribution width changes and postoperative acute kidney injury in patients with renal insufficiency: a retrospective study Open
Not applicable for this observational retrospective study.
View article: Modified furosemide responsiveness index and biomarkers for AKI progression and prognosis: a prospective observational study
Modified furosemide responsiveness index and biomarkers for AKI progression and prognosis: a prospective observational study Open
Background Modified furosemide responsiveness index (mFRI) is a novel biomarker for assessing diuretic response and AKI progression in patients with early AKI. However, the comparative predictive performance of mFRI and novel renal biomark…
View article: Development and external validation of a novel modality for rapid recognition of aortic dissection based on peripheral pulse oximetry waveforms
Development and external validation of a novel modality for rapid recognition of aortic dissection based on peripheral pulse oximetry waveforms Open
Background Aortic dissection (AD) is a life‐threatening cardiovascular emergency that is often misdiagnosed as other chest pain conditions. Physiologically, AD may cause abnormalities in peripheral blood flow, which can be detected using p…
View article: Predictive value of perioperative NT-proBNP levels for acute kidney injury in patients with compromised renal function undergoing cardiac surgery: a case control study
Predictive value of perioperative NT-proBNP levels for acute kidney injury in patients with compromised renal function undergoing cardiac surgery: a case control study Open
Perioperative NT-proBNP level changes are predictive of postoperative AKI in patients with pre-existing renal deficiencies undergoing cardiac surgery, aiding in risk assessment and patient management.
View article: Genomic structural variations link multiple genes to bone mineral density in a multi-ethnic cohort study: Louisiana osteoporosis study
Genomic structural variations link multiple genes to bone mineral density in a multi-ethnic cohort study: Louisiana osteoporosis study Open
Osteoporosis, characterized by low BMD, is a highly heritable metabolic bone disorder. Although single nucleotide variations (SNVs) have been extensively studied, they explain only a fraction of BMD heritability. Although genomic structura…
View article: [Sanguinarine alleviates ulcerative colitis in mice by regulating the Nrf2/NF-κB pathway].
[Sanguinarine alleviates ulcerative colitis in mice by regulating the Nrf2/NF-κB pathway]. Open
SA can improve UC-like enteritis in mice possibly by activating the Nrf2 pathway and inhibiting the NF-κB pathway in the colon tissue.
View article: Assessing the predictive value of elevated postoperative syndecan-1 levels for progressive acute kidney injury and kidney replacement therapy necessity in adult cardiac surgery patients
Assessing the predictive value of elevated postoperative syndecan-1 levels for progressive acute kidney injury and kidney replacement therapy necessity in adult cardiac surgery patients Open
Elevated postoperative SDC-1 levels significantly predict AKI progression and AKI-KRT in patients following cardiac surgery. The study's findings support incorporating SDC-1 level monitoring into post-surgical care to improve early detecti…
View article: Compressed point cloud classification with point-based edge sampling
Compressed point cloud classification with point-based edge sampling Open
3D point cloud data, as an immersive detailed data source, has been increasingly used in numerous applications. To deal with the computational and storage challenges of this data, it needs to be compressed before transmission, storage, and…
View article: AKI-Pro score for predicting progression to severe acute kidney injury or death in patients with early acute kidney injury after cardiac surgery
AKI-Pro score for predicting progression to severe acute kidney injury or death in patients with early acute kidney injury after cardiac surgery Open
Background No reliable clinical tools exist to predict acute kidney injury (AKI) progression. We aim to explore a scoring system for predicting the composite outcome of progression to severe AKI or death within seven days among early AKI p…
View article: DPER: Diffusion Prior Driven Neural Representation for Limited Angle and Sparse View CT Reconstruction
DPER: Diffusion Prior Driven Neural Representation for Limited Angle and Sparse View CT Reconstruction Open
Limited-angle and sparse-view computed tomography (LACT and SVCT) are crucial for expanding the scope of X-ray CT applications. However, they face challenges due to incomplete data acquisition, resulting in diverse artifacts in the reconst…
View article: Editorial: Advances in extracorporeal life support in critically ill patients, volume III
Editorial: Advances in extracorporeal life support in critically ill patients, volume III Open
EDITORIAL article Front. Med., 26 March 2024Sec. Intensive Care Medicine and Anesthesiology Volume 11 - 2024 | https://doi.org/10.3389/fmed.2024.1394830