Siyan Zhan
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View article: Attitudes Toward Common Data Models Among Chinese Biomedical Professionals: Cross-Sectional Survey
Attitudes Toward Common Data Models Among Chinese Biomedical Professionals: Cross-Sectional Survey Open
Background In the rapidly evolving landscape of health informatics, adopting a standardized common data model (CDM) is a pivotal strategy for harmonizing data from diverse sources within a cohesive framework. Transitioning regional databas…
View article: Correction: A partially randomized patient preference trial to assess the quality of life and patency rate after minimally invasive cardiac surgery-coronary artery bypass grafting: design and rationale of the MICS-CABG PRPP trial
Correction: A partially randomized patient preference trial to assess the quality of life and patency rate after minimally invasive cardiac surgery-coronary artery bypass grafting: design and rationale of the MICS-CABG PRPP trial Open
[This corrects the article DOI: 10.3389/fcvm.2022.804217.].
View article: Traditional Chinese medicine use and risk of type 2 diabetes mellitus among patients with prediabetes: a population-based cohort study
Traditional Chinese medicine use and risk of type 2 diabetes mellitus among patients with prediabetes: a population-based cohort study Open
Background Prediabetes was a reversible process in the development of type 2 diabetes mellitus (T2DM). Traditional Chinese medicine (TCM) was used to regulate blood glucose for thousands of years. However, there was a lack of real-world ev…
View article: Seven-Year Intervention Rate and Effect of Early Rehabilitation in China
Seven-Year Intervention Rate and Effect of Early Rehabilitation in China Open
The improvement of early rehabilitation service capacity is of great importance for meeting health needs of the population; however, there is still a lack of information on early rehabilitation interventions in hospitals in China. This stu…
View article: The ChinaSTAD Chinese Registry in Patients with Moderate-To-Severe Atopic Dermatitis Not Controlled by Topical Therapy: Baseline Characteristics, Disease Burden and Treatment
The ChinaSTAD Chinese Registry in Patients with Moderate-To-Severe Atopic Dermatitis Not Controlled by Topical Therapy: Baseline Characteristics, Disease Burden and Treatment Open
NCT05023668.
View article: Post-marketing surveillance for the safety of the quadrivalent human papillomavirus vaccine: a retrospective real-world study in China
Post-marketing surveillance for the safety of the quadrivalent human papillomavirus vaccine: a retrospective real-world study in China Open
These findings confirm the favorable benefit/risk profile of the 4vHPV vaccine in Chinese women in the routine healthcare setting.
View article: Risk factors of axial symptoms after posterior cervical spine surgery: a meta-analysis
Risk factors of axial symptoms after posterior cervical spine surgery: a meta-analysis Open
Preoperative neck pain, facet joints destruction, C7 spinous process(muscle)destruction, conventional posterior cervical spine surgery and C2 involvement were risk factors for postoperative axial symptoms after posterior cervical spine sur…
View article: Research on NEV Consumption and Co-Development in Tianjin: Based on the Policy-Technology-Demand Framework and AI-Driven Empirical Analysis
Research on NEV Consumption and Co-Development in Tianjin: Based on the Policy-Technology-Demand Framework and AI-Driven Empirical Analysis Open
Against the backdrop of global carbon reduction strategies and the rapid development of artificial intelligence, this study focuses on the new energy vehicle market in Tianjin, employing questionnaire surveys, in-depth interviews, and empi…
View article: Patient journey and Quality of Life for Patients with Idiopathic Pulmonary Fibrosis (IPFLife) in China: a sequential exploratory mixed methods research protocol
Patient journey and Quality of Life for Patients with Idiopathic Pulmonary Fibrosis (IPFLife) in China: a sequential exploratory mixed methods research protocol Open
Introduction Idiopathic pulmonary fibrosis (IPF) is a rare, chronic and progressive lung disease with a significant impact on patients’ quality of life. While much research has focused on disease mechanisms and treatment efficacy, limited …
View article: Artificial intelligence empowering evidence-based medicine: an L0-L5 evolutionary framework toward personalized precision medicine
Artificial intelligence empowering evidence-based medicine: an L0-L5 evolutionary framework toward personalized precision medicine Open
View article: Impacts of COPD exacerbation history on mortality and severe cardiovascular events among patients with COPD in China: a retrospective cohort study
Impacts of COPD exacerbation history on mortality and severe cardiovascular events among patients with COPD in China: a retrospective cohort study Open
View article: Reviews of "Age-specific Immunity to Rotavirus Infection and the Risk of Disease Before and After Rotavirus Vaccine Introduction in the United Kingdom: An Observational, Seroepidemiological Study"
Reviews of "Age-specific Immunity to Rotavirus Infection and the Risk of Disease Before and After Rotavirus Vaccine Introduction in the United Kingdom: An Observational, Seroepidemiological Study" Open
View article: Review 1: "Age-specific Immunity to Rotavirus Infection and the Risk of Disease Before and After Rotavirus Vaccine Introduction in the United Kingdom: An Observational, Seroepidemiological Study"
Review 1: "Age-specific Immunity to Rotavirus Infection and the Risk of Disease Before and After Rotavirus Vaccine Introduction in the United Kingdom: An Observational, Seroepidemiological Study" Open
View article: Role of senescent CD4+ T cells in breakthrough infection of the new variant strain of SARS-CoV-2 in elderly patients
Role of senescent CD4+ T cells in breakthrough infection of the new variant strain of SARS-CoV-2 in elderly patients Open
We found the immunological efficacy of inactivated vaccines in elderly patients is influenced by the proportion of CD4+ senescent T cells. Future elderly vaccination strategies need optimization in dose number and timing, and fu…
View article: Treatment Patterns and Triple Therapy Utilization in Chinese Patients with Chronic Obstructive Pulmonary Disease: An Analysis of Real-World Data from the Yinzhou Database
Treatment Patterns and Triple Therapy Utilization in Chinese Patients with Chronic Obstructive Pulmonary Disease: An Analysis of Real-World Data from the Yinzhou Database Open
Our study assessed treatment patterns and triple therapy utilization among patients with COPD in China. The majority of patients were treated with ICS+LABA dual therapy. Triple therapy was also widely used, with most patients transitioning…
View article: Antihypertensive medications and cancer risk: Evidence from 0.27 million patients with newly diagnosed hypertension
Antihypertensive medications and cancer risk: Evidence from 0.27 million patients with newly diagnosed hypertension Open
Background Whether specific antihypertensive treatments increase cancer risk in patients with hypertension is still controversial. We aimed to estimate the associations of different antihypertensive treatments with cancer risk in real-worl…
View article: [Prevalence characteristics of autoimmune thyroid disease in women aged 10-59 years in Qingdao City from 2022 to 2024].
[Prevalence characteristics of autoimmune thyroid disease in women aged 10-59 years in Qingdao City from 2022 to 2024]. Open
The three-year pre-valence of HT and GD in females aged 10-59 years in Qingdao City from 2022 to 2024 is low, but the annual prevalence is on the rise, and the three-year prevalence of HT and GD in females aged 25-39 years is higher than t…
View article: [Epidemiological characteristics of febrile seizure among children under 6 years old in Ningbo City from 2015 to 2021].
[Epidemiological characteristics of febrile seizure among children under 6 years old in Ningbo City from 2015 to 2021]. Open
From 2015 to 2019, the overall incidence density of FS in children under 6 years old in Ningbo City presented an increasing trend. More attention should be paid to the health education, the improvement of the health maintenance model, the …
View article: Minimum Data Set and Metadata for Active Vaccine Safety Surveillance: Systematic Review
Minimum Data Set and Metadata for Active Vaccine Safety Surveillance: Systematic Review Open
Background Active vaccine safety surveillance (AVSS) stands as a top priority for the World Health Organization (WHO), serving as a critical indicator of the fourth maturity level for national regulatory agencies. Objective This review aim…
View article: Efficient Big Data Processing and Recommendation System Development with Apache Spark
Efficient Big Data Processing and Recommendation System Development with Apache Spark Open
The rapid development of big data analytics has revolutionized data analysis and decision-making processes across industries. This paper explores how to use Apache Spark to analyze the MovieLens 20M dataset and identify the top movies in M…
View article: Machine Learning-Based Parking Occupancy Prediction Using OpenStreetMap Data
Machine Learning-Based Parking Occupancy Prediction Using OpenStreetMap Data Open
Accurate parking occupancy prediction is essential for reducing traffic congestion and optimizing urban mobility. Traditional monitoring methods are costly and difficult to scale, making machine learning a viable alternative. This study em…
View article: Use of ultrasonic left ventricular pressure-strain loops to predict weaning failure in critically ill patients: a pilot study
Use of ultrasonic left ventricular pressure-strain loops to predict weaning failure in critically ill patients: a pilot study Open
PSLs can be used to effectively evaluate myocardial work during weaning. GWE is an important myocardial work parameter, and could serve as an independent risk factor for accurately evaluating weaning outcomes.
View article: Uptake of the IMMPACT-recommended core outcome set in randomised controlled trials on chronic neck or shoulder pain: a cross-sectional study
Uptake of the IMMPACT-recommended core outcome set in randomised controlled trials on chronic neck or shoulder pain: a cross-sectional study Open
Objective To analyse the uptake rate of Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)-recommended core outcome set (COS) in randomised controlled trials (RCTs) on chronic neck or shoulder pain and its…
View article: Transforming Care in China by Using Public–Private Partnerships to Unlock the Power of Patient-Centered Real-World Data
Transforming Care in China by Using Public–Private Partnerships to Unlock the Power of Patient-Centered Real-World Data Open
The transformation of China's healthcare system is increasingly driven by the development of real-world data (RWD) and real-world evidence (RWE). In the context of the "Healthy China 2030" initiative, which emphasizes addressing the growin…
View article: Impact of fixed appliance treatment on root resorption in root canal-treated teeth: a systematic review and meta-analysis
Impact of fixed appliance treatment on root resorption in root canal-treated teeth: a systematic review and meta-analysis Open
Objective: The relationship between orthodontic treatment and root resorption in endodontically treated teeth remains controversial. This systematic review and meta-analysis aimed to evaluate the effects of fixed appliance treatment on roo…
View article: Attitudes Toward Common Data Models Among Chinese Biomedical Professionals: Cross-Sectional Survey (Preprint)
Attitudes Toward Common Data Models Among Chinese Biomedical Professionals: Cross-Sectional Survey (Preprint) Open
BACKGROUND In the rapidly evolving landscape of health informatics, adopting a standardized common data model (CDM) is a pivotal strategy for harmonizing data from diverse sources within a cohesive framework. Transitioning regional databa…
View article: Dissecting the bidirectional associations between the progression of gastrointestinal and endocrine diseases
Dissecting the bidirectional associations between the progression of gastrointestinal and endocrine diseases Open
Backgrounds The widespread intrinsic link between gastrointestinal and endocrine diseases was poorly understood. We aimed to dissect the bidirectional association in the progression of gastrointestinal with endocrine diseases, either the o…
View article: Application of a Digital Injury-Surveillance Platform
Application of a Digital Injury-Surveillance Platform Open
This cross-sectional study evaluates the validity of a digital injury-surveillance platform in Yinzhou, China.
View article: Feasibility of Closed-Loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine: A Randomized Controlled Equivalence Trial
Feasibility of Closed-Loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine: A Randomized Controlled Equivalence Trial Open
It is feasible to operate the closed-loop TCI system based on the adjusted BIS baseline in the presence of low dose of esketamine.
View article: Association between use of sodium-glucose cotransporter-2 inhibitors and epilepsy: A population-based study using target trial emulation
Association between use of sodium-glucose cotransporter-2 inhibitors and epilepsy: A population-based study using target trial emulation Open
Objective: Preclinical studies in animals suggested potential neuroprotective effects of sodium-glucose co-transporter 2 inhibitors (SGLT-2i), but no epidemiological study has investigated the potential effects of SGLT-2i on epilepsy risk.…