Ziwen He
YOU?
Author Swipe
View article: An antibody-dependent cellular phagocytosis-related gene signature predicts survival and response to immunotherapy in stomach adenocarcinoma
An antibody-dependent cellular phagocytosis-related gene signature predicts survival and response to immunotherapy in stomach adenocarcinoma Open
Antibody-dependent cellular phagocytosis (ADCP) is an immune biological process and plays a biological role in the clearance of tumor cells and the response to immune checkpoint inhibitors. However, the effects of ADCP on stomach adenocarc…
View article: CpG‐Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2‐Mediated Remodeling of Tumor‐Associated Macrophages
CpG‐Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2‐Mediated Remodeling of Tumor‐Associated Macrophages Open
CpG oligodeoxynucleotides (CpG), as an immunoadjuvant, can facilitate the transformation of tumor‐associated macrophages (TAMs)into tumoricidal M1 macrophages. However, the accumulation of free CpG in tumor tissues remains a substantial ch…
View article: Effects of Hsa-miR-4741/LILRB2 on Senescence of Nucleus Pulposus Cells and Their Prognostic Values in Lumbar Disc Herniation
Effects of Hsa-miR-4741/LILRB2 on Senescence of Nucleus Pulposus Cells and Their Prognostic Values in Lumbar Disc Herniation Open
The combination of hsa-miR-4741 and LILRB2 was a good predictor of LDH prognosis. Hsa-miR-4741 promoted oxidative stress-induced NPC senescence by negatively regulating LILRB2.
View article: An Underactuated Dexterous Hand with Novel Bidirectional Self-Locking Joints for Multiple Fingertip Active Motion Trajectories
An Underactuated Dexterous Hand with Novel Bidirectional Self-Locking Joints for Multiple Fingertip Active Motion Trajectories Open
This paper proposes an underactuated dexterous hand with novel bidirectional self-locking joints (BSJs) that enable multiple fingertip motion trajectories. The BSJ design integrates a locking wheel, rack, finger side walls, and a self-hold…
View article: Cordyceps polysaccharide improves polycystic ovary syndrome by inhibiting gut-derived LPS/TLR4 pathway to attenuates insulin resistance
Cordyceps polysaccharide improves polycystic ovary syndrome by inhibiting gut-derived LPS/TLR4 pathway to attenuates insulin resistance Open
Polycystic ovary syndrome (PCOS) is an endocrine disorder marked by aberrant glucose metabolism and reproductive dysfunction. It is characterized by polycystic ovaries, ovulatory dysfunction, and hyperandrogenemia. PCOS patients often expe…
View article: Ss4368: Pathogen-Associated Molecular Pattern for Inducing Plant Cell Death and Resistance to Phytophthora capsici
Ss4368: Pathogen-Associated Molecular Pattern for Inducing Plant Cell Death and Resistance to Phytophthora capsici Open
Plant recognition of pathogen-associated molecular patterns (PAMPs) is pivotal in triggering immune responses, highlighting their potential as inducers of plant immunity. However, the number of PAMPs identified and applied in such contexts…
View article: Adaptation in Unstable Environments and Global Gene Losses: Small but Stable Gene Networks by the May–Wigner Theory
Adaptation in Unstable Environments and Global Gene Losses: Small but Stable Gene Networks by the May–Wigner Theory Open
Although gene loss is common in evolution, it remains unclear whether it is an adaptive process. In a survey of seven major mangrove clades that are woody plants in the intertidal zones of daily environmental perturbations, we noticed that…
View article: The evolution history of an allotetraploid mangrove tree analysed with a new tool Allo4D
The evolution history of an allotetraploid mangrove tree analysed with a new tool Allo4D Open
Summary Mangrove species are broadly classified as true mangroves and mangrove associates. The latter are amphibious plants that can survive in the intertidal zone and reproduce naturally in terrestrial environments. Their widespread distr…
View article: How does high-speed railway affect green technology innovation? A perspective of high-quality human capital
How does high-speed railway affect green technology innovation? A perspective of high-quality human capital Open
Green development is the main theme of modern development in China and even the world. Green development depends on green technology innovation (GTI). Therefore, for developing countries like China in the stage of economic transition, it i…
View article: Evolution of sea‐surfing plant propagule as revealed by the genomes of <i>Heritiera</i> mangroves
Evolution of sea‐surfing plant propagule as revealed by the genomes of <i>Heritiera</i> mangroves Open
SUMMARY Coastal forests, such as mangroves, protect much of the tropical and subtropical coasts. Long‐distance dispersal via sea‐surfing propagules is essential for coastal plants, but the genomic and molecular basis of sea‐surfing plant p…
View article: The role of green technology innovation on employment: does industrial structure optimization and air quality matter?
The role of green technology innovation on employment: does industrial structure optimization and air quality matter? Open
Although green technology innovation is an important means to balance the environment and economy, few studies have analyzed the employment effects of green technology innovation in developing countries. Therefore, this paper employs the p…
View article: Seasonal Variation in Bacterial Community Structures of Mangrove Sediments
Seasonal Variation in Bacterial Community Structures of Mangrove Sediments Open
Climate change globally and sea level rise affect the mangrove ecosystem. The high diversity and temporal heterogeneity of the mangrove ecosystem will lead to a high diversity of sediment bacterial community structure and function. However…
View article: Chromosomal-Scale Genome Assemblies of Two Coastal Plant Species, Scaevola taccada and S. hainanensis—Insight into Adaptation Outside of the Common Range
Chromosomal-Scale Genome Assemblies of Two Coastal Plant Species, Scaevola taccada and S. hainanensis—Insight into Adaptation Outside of the Common Range Open
While most of the species in Goodeniaceae family, excluding the Scaevola genus, are endemic to Australasia, S. taccada and S. hainanensis have expanded their distribution range to the tropical coastlines of the Atlantic and Indian Oceans. …
View article: A Key to Stimulate Green Technology Innovation in China: The Expansion of High-Speed Railways
A Key to Stimulate Green Technology Innovation in China: The Expansion of High-Speed Railways Open
Mankind is seeking a green development path. This paper places emphasis on whether high-speed railways (HSRs), as a typical representative of green transportation, can effectively promote green technology innovation in cities. Based on the…
View article: Sympatric or micro-allopatric speciation in a glacial lake? Genomic islands support neither
Sympatric or micro-allopatric speciation in a glacial lake? Genomic islands support neither Open
Apparent cases of sympatric speciation may actually be due to micro-allopatric or micro-parapatric speciation. One way to distinguish between these models is to examine the existence and nature of genomic islands of divergence, wherein div…
View article: Extensive gene flow in secondary sympatry after allopatric speciation
Extensive gene flow in secondary sympatry after allopatric speciation Open
In the conventional view, species are separate gene pools delineated by reproductive isolation (RI). In an alternative view, species may also be delineated by a small set of ‘speciation genes’ without full RI, a view that has gained broad …
View article: The beneficial effects of Polygonatum sibiricum Red. superfine powder on metabolic hypertensive rats via gut-derived LPS/TLR4 pathway inhibition
The beneficial effects of Polygonatum sibiricum Red. superfine powder on metabolic hypertensive rats via gut-derived LPS/TLR4 pathway inhibition Open
We demonstrated the beneficial effects and potential mechanisms of PSP in our MH rat model. Based on gut microbiota structure modulation and intestinal barrier improvements, PSP inhibited LPS-induced vascular TLR4/MyD88 signaling activatio…
View article: [Clinical features of immune checkpoint inhibitor-related myositis in patients with urological cancer].
[Clinical features of immune checkpoint inhibitor-related myositis in patients with urological cancer]. Open
Immune-related myositis after ICI treatment is an immune-related adverse reactions (irAEs) with unique clinical and pathological features, commonly combined with cardiovascular adverse reactions. Immediate discontinuation of ICI and initia…
View article: Different types of industrial agglomeration and green total factor productivity in China: do institutional and policy characteristics of cities make a difference?
Different types of industrial agglomeration and green total factor productivity in China: do institutional and policy characteristics of cities make a difference? Open
This paper applies panel data of 281 prefecture-level cities in China from 2004 to 2017 to calculate the green total factor productivity (GTFP) at the city level. Then, it examines the influences of various forms of industrial agglomeratio…
View article: The twin-beginnings of COVID-19 in Asia and Europe—one prevails quickly
The twin-beginnings of COVID-19 in Asia and Europe—one prevails quickly Open
In the spread of SARS-CoV-2, there have been multiple waves of replacement between strains, each of which having a distinct set of mutations. The first wave is a group of four mutations (C241T, C3037T, C14408T and A23403G [this being the a…
View article: Lateral-Torsional Buckling Analysis for Doubly Symmetric Tubular Flange Composite Beams with Lateral Bracing under Concentrated Load
Lateral-Torsional Buckling Analysis for Doubly Symmetric Tubular Flange Composite Beams with Lateral Bracing under Concentrated Load Open
Tubular flange composite beams are increasingly applied in modern bridge structures. In order to investigate the overall stability behavior of doubly symmetric tubular flange composite beams with lateral bracing under concentrated load, th…
View article: Two decades of suspect evidence for adaptive molecular evolution—negative selection confounding positive-selection signals
Two decades of suspect evidence for adaptive molecular evolution—negative selection confounding positive-selection signals Open
There has been a large literature in the last two decades affirming adaptive DNA sequence evolution between species. The main lines of evidence are from (i) the McDonald-Kreitman (MK) test, which compares divergence and polymorphism data, …
View article: Two decades of suspect evidence for adaptive molecular evolution – Negative selection confounding positive selection signals
Two decades of suspect evidence for adaptive molecular evolution – Negative selection confounding positive selection signals Open
There is a large literature in the last two decades affirming adaptive DNA sequences evolution between species. The main lines of evidence are from i) the McDonald-Kreitman (MK) test, which compares divergence and polymorphism data, and ii…