Mengxing Wang
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View article: The effect of pitch accents on the interpretation of short exchanges by Dutch-English and French-English bilinguals
The effect of pitch accents on the interpretation of short exchanges by Dutch-English and French-English bilinguals Open
This study explores whether Dutch and French bilinguals leverage pitch accents to resolve sentence ambiguity in English (second language, L2) and how their native language (L1) and L2 level affects this process. Pitch accents, a key prosod…
View article: Serum Oxidative Stress Biomarkers (MDA, SOD, GSH-Px) and IL-6/TNF-α Ratio as Biochemical Indicators of Disease Progression in Pediatric Cariogenic Pulpitis
Serum Oxidative Stress Biomarkers (MDA, SOD, GSH-Px) and IL-6/TNF-α Ratio as Biochemical Indicators of Disease Progression in Pediatric Cariogenic Pulpitis Open
Background: Cariogenic pulpitis is a common pediatric oral disease in which oxidative stress and inflammatory imbalance are increasingly recognized as important pathogenic mechanisms. Biochemical markers such as malondialdehyde (MDA), supe…
View article: Cerebral Microbleeds and the Effect of Early Antihypertensive Treatment in Patients with Acute Ischemic Stroke: A Secondary Analysis of the CATIS-2 Trial
Cerebral Microbleeds and the Effect of Early Antihypertensive Treatment in Patients with Acute Ischemic Stroke: A Secondary Analysis of the CATIS-2 Trial Open
Background and Objectives To explore whether the presence, burden or distribution of cerebral microbleeds (CMBs) modifies the effect of early versus delayed antihypertensive treatment on clinical outcomes in acute ischemic stroke (AIS) pat…
View article: Effect of Stroke Severity on Efficacy and Safety of Indobufen versus Aspirin in Patients with Moderate to Severe Stroke: Results from the INSURE Randomized Clinical Trial
Effect of Stroke Severity on Efficacy and Safety of Indobufen versus Aspirin in Patients with Moderate to Severe Stroke: Results from the INSURE Randomized Clinical Trial Open
This exploratory analysis indicates that the benefit of indobufen in reducing new strokes within 3 months may vary across stroke severity. The potential non-inferiority of indobufen relative to aspirin in patients with NIHSS scores of ≥ 7,…
View article: Dual Antiplatelet Therapy in Patients With Metabolic Syndrome After Mild Ischemic Stroke or Transient Ischemic Attack
Dual Antiplatelet Therapy in Patients With Metabolic Syndrome After Mild Ischemic Stroke or Transient Ischemic Attack Open
Background Metabolic syndrome (MetS) attenuates antiplatelet agent effects. This study investigated the efficacy and safety of clopidogrel–aspirin therapy for secondary stroke prevention in patients with MetS. Methods Data were obtained fr…
View article: Predictors of futile recanalisation in patients with large infarct: a post-hoc analysis of the ANGEL-ASPECT trial
Predictors of futile recanalisation in patients with large infarct: a post-hoc analysis of the ANGEL-ASPECT trial Open
Background Studies on futile recanalisation after endovascular therapy (EVT) for anterior circulation large vessel occlusion with large infarct were scarce. The present study aimed to explore the incidence and independent predictors of fut…
View article: Influence of impaired renal function on the outcomes of patients with acute ischaemic stroke treated with intravenous tenecteplase and alteplase: a post hoc analysis of the TRACE-2 trial
Influence of impaired renal function on the outcomes of patients with acute ischaemic stroke treated with intravenous tenecteplase and alteplase: a post hoc analysis of the TRACE-2 trial Open
Objective Limited evidence is available regarding the risk-benefit ratio of thrombolytic therapy in patients with stroke and renal impairment complications, particularly for the drug tenecteplase. Therefore, we examined the association of …
View article: Cerebral Edema Progression and Outcomes in Large Infarct Patients Undergoing Endovascular Thrombectomy
Cerebral Edema Progression and Outcomes in Large Infarct Patients Undergoing Endovascular Thrombectomy Open
Objective The goal was to analyze the progression of cerebral edema post‐endovascular thrombectomy (EVT) in large infarcts and its association with functional outcomes. Methods A secondary analysis of the Endovascular Therapy in Acute Ante…
View article: Prognostic Impact of 1‐Year Changes in Creatinine‐ and Cystatin C‐Based Estimated Glomerular Filtration Rate After Stroke on 5‐Year Outcomes: Insights From the Third China National Stroke Registry
Prognostic Impact of 1‐Year Changes in Creatinine‐ and Cystatin C‐Based Estimated Glomerular Filtration Rate After Stroke on 5‐Year Outcomes: Insights From the Third China National Stroke Registry Open
Background The impact of long‐term renal function change on stroke outcomes remains unclear. This study used the CNSR‐III (Third China National Stroke Registry) cohort to determine whether changes in estimated glomerular filtration rate ba…
View article: The neural mechanism underlying Statistical Learning's contribution to L2 grammar learning
The neural mechanism underlying Statistical Learning's contribution to L2 grammar learning Open
View article: Correlated factors of posttraumatic growth in patients with colorectal cancer: A systematic review and meta-analysis
Correlated factors of posttraumatic growth in patients with colorectal cancer: A systematic review and meta-analysis Open
This meta-analysis identified 23 factors associated with PTG in CRC patients. Medical workers can combine those relevant factors from the perspective of positive psychology, further explore the occurrence and development mechanism of PTG, …
View article: Accelerated biological aging increases the risk of short- and long-term stroke prognosis in patients with ischemic stroke or TIA
Accelerated biological aging increases the risk of short- and long-term stroke prognosis in patients with ischemic stroke or TIA Open
View article: The Resting‐State Activities of the Angular Gyrus and the Micturition Desire‐Awakening Function in Children With and Without Enuresis
The Resting‐State Activities of the Angular Gyrus and the Micturition Desire‐Awakening Function in Children With and Without Enuresis Open
Background Micturition desire‐awakening (MDA) function plays a pivotal role in the development of primary nocturnal enuresis (PNE); however, its neural correlates remain largely unexplored. Consequently, this study aimed to identify specif…
View article: Association between stroke subtypes and outcomes of endovascular therapy: a post-hoc analysis of the ANGEL-ASPECT Trial
Association between stroke subtypes and outcomes of endovascular therapy: a post-hoc analysis of the ANGEL-ASPECT Trial Open
Objectives Our study aims to examine the value of endovascular therapy (EVT) and its comparison to medical management (MM) in ischaemic stroke patients accompanied by large artery atherosclerosis (LAA) and non-LAA Methods modified Rankin s…
View article: Early vs Delayed Antihypertensive Treatment in Acute Single Subcortical Infarction
Early vs Delayed Antihypertensive Treatment in Acute Single Subcortical Infarction Open
Importance The China Antihypertensive Trial in Acute Ischemic Stroke II (CATIS-2) suggests that early antihypertensive treatment did not reduce the risk of dependency or death in acute ischemic stroke (AIS), compared with delayed treatment…
View article: Anaesthesia modality on endovascular therapy outcomes in patients with large infarcts: a post hoc analysis of the ANGEL-ASPECT trial
Anaesthesia modality on endovascular therapy outcomes in patients with large infarcts: a post hoc analysis of the ANGEL-ASPECT trial Open
Objectives Endovascular therapy (EVT) now penetrates the once obscure realm of large infarct core volume acute ischaemic stroke (LICV-AIS). This research aimed to investigate the potential correlation between different anaesthetic approach…
View article: Obesity and brain volumes: mediation by cardiometabolic and inflammatory measures
Obesity and brain volumes: mediation by cardiometabolic and inflammatory measures Open
Background This study aimed to investigate the relationship between overall obesity, central obesity and brain volumes, as well as to determine the extent to which cardiometabolic and inflammatory measures act as mediators in the associati…
View article: Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial
Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial Open
Background The benefit–risk profile of tenecteplase in the elderly patients with acute ischaemic stroke (AIS) is uncertain. We sought to investigate the efficacy and safety of 0.25 mg/kg tenecteplase compared with alteplase for AIS patient…
View article: Associations of life’s essential 8 with extent of multi-territorial atherosclerotic plaques and stenosis: a cross-sectional study
Associations of life’s essential 8 with extent of multi-territorial atherosclerotic plaques and stenosis: a cross-sectional study Open
Background Life’s Essential 8 (LE8), the recently updated construct for quantifying cardiovascular health, is related to the risks of cardiovascular events. The present study aimed to evaluate associations of LE8 score with the multi-terri…
View article: Effectiveness and safety of bridging therapy and endovascular therapy in patients with large cerebral infarctions: from ANGEL-ASPECT
Effectiveness and safety of bridging therapy and endovascular therapy in patients with large cerebral infarctions: from ANGEL-ASPECT Open
Background and purpose The benefits of thrombolytic therapy before endovascular thrombectomy in cases of acute ischaemic stroke, with a large infarction volume, remain unclear. This analysis aims to evaluate the effectiveness and safety of…
View article: Inflammation and Adverse Outcomes in Patients With Acute Ischemic Stroke With and Without Chronic Kidney Disease
Inflammation and Adverse Outcomes in Patients With Acute Ischemic Stroke With and Without Chronic Kidney Disease Open
Background Elevated white blood cell count, fibrinogen levels, and lower levels of albumin signify higher systemic inflammatory response, hypercoagulable state, and poorer nutritional status, respectively. However, a consistent conclusion …
View article: Endovascular therapy in acute ischaemic stroke with large infarction with matched or mismatched clinical-radiological severities: a post-hoc analysis of the ANGEL-ASPECT trial
Endovascular therapy in acute ischaemic stroke with large infarction with matched or mismatched clinical-radiological severities: a post-hoc analysis of the ANGEL-ASPECT trial Open
View article: Periaqueductal gray subregions connectivity and its association with micturition desire-awakening function
Periaqueductal gray subregions connectivity and its association with micturition desire-awakening function Open
Purpose Existing literature strongly supports the idea that children with primary nocturnal enuresis (PNE) have a delayed brainstem maturation. However, the connection between pre-micturition arousal responses and brain functional connecti…
View article: Association of metabolic dysfunction-associated fatty liver disease with systemic atherosclerosis: a community-based cross-sectional study
Association of metabolic dysfunction-associated fatty liver disease with systemic atherosclerosis: a community-based cross-sectional study Open
Background Data are limited on the association of metabolic dysfunction-associated fatty liver disease (MAFLD) with systemic atherosclerosis. This study aimed to examine the relationship between MAFLD and the extent of atherosclerotic plaq…
View article: <italic>N</italic>-Sided Hole Filling Algorithm Based on GNURBS
<italic>N</italic>-Sided Hole Filling Algorithm Based on GNURBS Open
View article: Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct
Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct Open
Importance Endovascular therapy (EVT) demonstrated better outcomes compared with medical management in recent randomized clinical trials (RCTs) of patients with large infarct. Objective To compare outcomes of EVT vs medical management acro…
View article: Association between Life’s Essential 8 and Cerebral Small Vessel Disease
Association between Life’s Essential 8 and Cerebral Small Vessel Disease Open
Background Given that associations of Life’s Essential 8 (LE8) and cerebral small vessel disease (CSVD) or its imaging markers were unclear, we examined relationship between them. Methods The cross-sectional study included community reside…
View article: Optimal systolic and diastolic blood pressure threshold that associated with lower risk of white matter hyperintensity progression
Optimal systolic and diastolic blood pressure threshold that associated with lower risk of white matter hyperintensity progression Open
Background The optimal control thresholds for systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients with white matter hyperintensity (WMH) are still unclear. Method A longitudinal retrospective study of patients with…
View article: Predictors of futile recanalization in patients with large infarct: a post hoc analysis of the ANGEL-ASPECT trial
Predictors of futile recanalization in patients with large infarct: a post hoc analysis of the ANGEL-ASPECT trial Open
Background Few studies have focused on factors associated with futile recanalization in acute anterior circulation stroke patients with large infarct cores who were treated with modern endovascular therapy (EVT). The aim of this study was …
View article: High-Sensitivity C-reactive Protein and Intracranial Arterial Stenosis Predicted Recurrent Stroke and Dependence or Death in Minor Stroke or Transient Ischemic Attack
High-Sensitivity C-reactive Protein and Intracranial Arterial Stenosis Predicted Recurrent Stroke and Dependence or Death in Minor Stroke or Transient Ischemic Attack Open
Concomitant presence of increased hsCRP levels and ICAS was associated with increased risk of stroke recurrence and dependence or death in patients with minor ischemic stroke or transient ischemic attack.