Zhengtao Wang
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View article: Schisantherin A interacts with gut bacteria to stimulate adipose tissue thermogenesis in obese mice via a TGR5‒p-CREB‒STAT6 signaling pathway
Schisantherin A interacts with gut bacteria to stimulate adipose tissue thermogenesis in obese mice via a TGR5‒p-CREB‒STAT6 signaling pathway Open
View article: Corrigendum to “Vibration-assisted droplet microfluidic chip system for ultra-fast preparation of uniform, high-encapsulation polydopamine-shikonin nanoparticles combined with UV-curable fish collagen hydrogel for treating deep second-degree burns” [Chemical Engineering Journal 525 (2025) 169903]
Corrigendum to “Vibration-assisted droplet microfluidic chip system for ultra-fast preparation of uniform, high-encapsulation polydopamine-shikonin nanoparticles combined with UV-curable fish collagen hydrogel for treating deep second-degree burns” [Chemical Engineering Journal 525 (2025) 169903] Open
View article: Altered gut mycobiome and cross-kingdom microbial interactions in systemic lupus erythematosus
Altered gut mycobiome and cross-kingdom microbial interactions in systemic lupus erythematosus Open
View article: Explainable ensemble learning for Epstein-Barr virus risk prediction in ulcerative colitis and Crohn’s disease using routine biomarkers
Explainable ensemble learning for Epstein-Barr virus risk prediction in ulcerative colitis and Crohn’s disease using routine biomarkers Open
Epstein-Barr virus (EBV) exacerbates inflammatory bowel disease (IBD) and is challenging to monitor with invasive or costly tests. We investigated whether explainable machine learning can predict EBV infection from routine clinical data in…
View article: 20(S)-protopanaxatriol ameliorates cardiac hypertrophy by activating the AMPK/PGC-1α/PPARγ signaling pathway
20(S)-protopanaxatriol ameliorates cardiac hypertrophy by activating the AMPK/PGC-1α/PPARγ signaling pathway Open
View article: Distributed cortical learning through LEC-mediated γ-synchrony
Distributed cortical learning through LEC-mediated γ-synchrony Open
Despite the well-established theoretical and experimental foundations of dopamine-driven reinforcement learning, how the reward prediction error (RPE) teaching signal modifies specific cortical memory networks remains unclear. Neural oscil…
View article: Green Extraction Tree: A Novel Tool to Greenness Metric for Green Extraction of Natural Products
Green Extraction Tree: A Novel Tool to Greenness Metric for Green Extraction of Natural Products Open
A comprehensive and intuitive evaluation tool, termed the Green Extraction Tree (GET), has been developed to assess the greenness of the sample preparation process in the green extraction of natural products. The assessment criteria integr…
View article: Enhancement of UDP-Arabinose Supply and Engineering of Glycosyltransferase DaUGT121 from Dipsacus asperoides for Cauloside A Biosynthesis in Escherichia coli
Enhancement of UDP-Arabinose Supply and Engineering of Glycosyltransferase DaUGT121 from Dipsacus asperoides for Cauloside A Biosynthesis in Escherichia coli Open
View article: SoC Fusion Estimation Based on Neural Network Long and Short Time Series
SoC Fusion Estimation Based on Neural Network Long and Short Time Series Open
Accurate prediction of state-of-charge (SoC) is critical to ensure battery performance, extend lifetime and ensure safety. Data-driven methods for SoC prediction are highly adaptable and generalizable. However, the current method of estima…
View article: Gastrodin improves learning and memory in sleep-deprived mice through suppression of ferroptosis in hippocampal neurons via Nrf2
Gastrodin improves learning and memory in sleep-deprived mice through suppression of ferroptosis in hippocampal neurons via Nrf2 Open
Sleep deprivation (SD) causes various neurological deficits, including impaired learning and memory. Gastrodia elata (G. elata) is a traditional Chinese medicinal herb known for its effects in calming liver yang, dispelling winds, unblocki…
View article: Multi-omics revealed the promoting effect of dietary inulin supplementation on hepatic gluconeogenesis in goats
Multi-omics revealed the promoting effect of dietary inulin supplementation on hepatic gluconeogenesis in goats Open
Introduction Gluconeogenesis is the primary pathway for ruminants to obtain energy. Enhancement of gluconeogenesis can significantly improve the growth performance of ruminants. Inulin, a prebiotic, has capabilities such as fostering a hea…
View article: Monetary policy effect on income and wealth inequality mechanism
Monetary policy effect on income and wealth inequality mechanism Open
Since the 1990s, global income and wealth inequality has increased significantly, especially in developing countries, where the imbalance in wealth distribution has become increasingly prominent. This study seeks to thoroughly investigate …
View article: Correction: Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms
Correction: Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms Open
[This corrects the article DOI: 10.3389/fphar.2024.1449831.].
View article: Hepatic and intestinal tissue-specific <i>Fxr</i> deficiency alters bile acid homeostasis in female mice
Hepatic and intestinal tissue-specific <i>Fxr</i> deficiency alters bile acid homeostasis in female mice Open
We successfully developed a double tissue-specific Fxr knockout (DKO) mouse model, which provides a novel tool for investigation of FXR functions in the liver and intestine. Unlike whole body KO, the DKO model excludes the FXR impact on ot…
View article: Language Pre-training Guided Masking Representation Learning for Time Series Classification
Language Pre-training Guided Masking Representation Learning for Time Series Classification Open
The representation learning of time series has a wide range of downstream tasks and applications in many practical scenarios. However, due to the complexity, spatiotemporality, and continuity of sequential stream data, compared with the re…
View article: Prunellate A: An Unprecedented Lignan Lactone with a 6/7/6/5-Fused Tetracycle Skeleton by C-2–C-2′ and C-7–C-8′ Linkage from the Chinese Medicinal Plant <i>Prunella vulgaris</i> Inhibiting the Activation of Hepatic Stellate Cells by Targeting FXR
Prunellate A: An Unprecedented Lignan Lactone with a 6/7/6/5-Fused Tetracycle Skeleton by C-2–C-2′ and C-7–C-8′ Linkage from the Chinese Medicinal Plant <i>Prunella vulgaris</i> Inhibiting the Activation of Hepatic Stellate Cells by Targeting FXR Open
Prunellate A (1), an unprecedented lignan lactone bearing a 6/7/6/5 tetracyclic system with C-2-C-2' and C-7-C-8' single bond linkage, probably derived from the rearrangement of methyl rosmarinate (2), has been isolated from …
View article: Chlorogenic acid attenuates pyrrolizidine alkaloid-induced liver injury through modulation of the SIRT1/FXR signaling pathway
Chlorogenic acid attenuates pyrrolizidine alkaloid-induced liver injury through modulation of the SIRT1/FXR signaling pathway Open
Background Pyrrolizidine alkaloids (PAs), recognized globally for their hepatotoxic properties, significantly contribute to liver damage through an imbalance in bile acid homeostasis. Addressing this imbalance is crucial for therapeutic in…
View article: Safranal Ameliorates Renal Damage, Inflammation, and Podocyte Injury in Membranous Nephropathy via SIRT/NF-κB Signalling
Safranal Ameliorates Renal Damage, Inflammation, and Podocyte Injury in Membranous Nephropathy via SIRT/NF-κB Signalling Open
View article: ChMER: an exoskeleton robot with active body weight support walker based on compliant actuation for children with cerebral palsy
ChMER: an exoskeleton robot with active body weight support walker based on compliant actuation for children with cerebral palsy Open
Introduction Lower limb exoskeleton robots for young children with cerebral palsy (CP) are crucial to support earlier rehabilitation that is more beneficial than later. For safety reasons, pediatric exoskeletons are usually equipped with b…
View article: Clinical characteristics of patients with pulsatile tinnitus accompanied by ethmoid sinus lesions and high jugular bulb
Clinical characteristics of patients with pulsatile tinnitus accompanied by ethmoid sinus lesions and high jugular bulb Open
PT patients are predominantly affected on the right side, primarily manifested as intermittent tinnitus. The severity of hearing loss and the presence of ESL + HJB are independent factors affecting the prognosis of PT patients.
View article: Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms
Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms Open
Background Sterofundin (SF) is one of the most widely used electrolyte solutions in almost all areas of medicine, with particular importance in intensive care. It provides powerful correction of acid-base imbalances, ion fluctuations, and …
View article: Bim-Based Construction Scheduling Optimization Through Graph Neural Network--Driven Spatial Semantic Reasoning
Bim-Based Construction Scheduling Optimization Through Graph Neural Network--Driven Spatial Semantic Reasoning Open
View article: MSCM: A geomagnetic model derived from Swarm, CSES, and MSS-1 satellite data and the evolution of the South Atlantic Anomaly
MSCM: A geomagnetic model derived from Swarm, CSES, and MSS-1 satellite data and the evolution of the South Atlantic Anomaly Open
Measurements from geomagnetic satellites continue to underpin advances in geomagnetic field models that describe Earth’s internally generated magnetic field. Here, we present a new field model, MSCM, that integrates vector and scalar data …
View article: When Capital Crosses Borders, So Does Knowledge
When Capital Crosses Borders, So Does Knowledge Open
View article: BIM-Based Construction Scheduling Optimization through Graph Neural Network--Driven Spatial Semantic Reasoning
BIM-Based Construction Scheduling Optimization through Graph Neural Network--Driven Spatial Semantic Reasoning Open
View article: 3D Enhanced Residual CNN for Video Super-Resolution Network
3D Enhanced Residual CNN for Video Super-Resolution Network Open
View article: Fixed-time adaptive neural network fault-tolerant control during the Belly Flip maneuver for a starship-like vehicle
Fixed-time adaptive neural network fault-tolerant control during the Belly Flip maneuver for a starship-like vehicle Open
View article: BIM-Based Spatial Semantic Reasoning and Lifecycle Management Driven by Heterogeneous Graph Neural Networks
BIM-Based Spatial Semantic Reasoning and Lifecycle Management Driven by Heterogeneous Graph Neural Networks Open
View article: MSC-derived exosomal circMYO9B accelerates diabetic wound healing by promoting angiogenesis through the hnRNPU/CBL/KDM1A/VEGFA axis
MSC-derived exosomal circMYO9B accelerates diabetic wound healing by promoting angiogenesis through the hnRNPU/CBL/KDM1A/VEGFA axis Open
Diabetic foot ulcer (DFU) is a common but devastating complication of diabetes mellitus and might ultimately lead to amputation. Elucidating the regulatory mechanism of wound healing in DFU is quite important for developing DFU management …
View article: Biological functions and pharmacological behaviors of bile acids in metabolic diseases
Biological functions and pharmacological behaviors of bile acids in metabolic diseases Open
Bile acids circulate primarily within the enterohepatic circulation, where they help maintain a healthy digestive system. Disruptions in their balance are linked to metabolic disorders, hepatobiliary diseases and intestinal inflammation. T…