Zhengyan Zhan
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View article: Analysis of the Countermeasures of Dealing with the Network Public Opinions on Emergencies of Colleges in Gansu Province
Analysis of the Countermeasures of Dealing with the Network Public Opinions on Emergencies of Colleges in Gansu Province Open
The popularity of the Internet and the rise of self-media have built a diversified, convenient and instant platform for colleges and universities to do a good job in education, teaching, propaganda and ideology, but at the same time it als…
View article: Archaeal Chromatin Proteins Cren7 and Sul7d Compact DNA by Bending and Bridging
Archaeal Chromatin Proteins Cren7 and Sul7d Compact DNA by Bending and Bridging Open
A long-standing question is how chromosomal DNA is packaged in Crenarchaeota, a major group of archaea, which synthesize large amounts of unique small DNA-binding proteins but in general contain no archaeal histones. In the present work, w…
View article: Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level
Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level Open
The fluorescence microscopy has made great contributions in dissecting the mechanisms of complex biological processes at the single molecule level. In single molecule assays for studying DNA-protein interactions, there are two important fa…
View article: Utilizing Biotinylated Proteins Expressed in Yeast to Visualize DNA–Protein Interactions at the Single-Molecule Level
Utilizing Biotinylated Proteins Expressed in Yeast to Visualize DNA–Protein Interactions at the Single-Molecule Level Open
Much of our knowledge in conventional biochemistry has derived from bulk assays. However, many stochastic processes and transient intermediates are hidden when averaged over the ensemble. The powerful technique of single-molecule fluoresce…
View article: Site-Specific Recombination by SSV2 Integrase: Substrate Requirement and Domain Functions
Site-Specific Recombination by SSV2 Integrase: Substrate Requirement and Domain Functions Open
SSV-type integrases, encoded by fuselloviruses which infect the hyperthermophilic archaea of the Sulfolobales , are archaeal members of the tyrosine recombinase family. These integrases catalyze viral integration into and excision from a s…