Zhenjun Hu
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View article: Inferring microbial co-occurrence networks from amplicon data: a systematic evaluation
Inferring microbial co-occurrence networks from amplicon data: a systematic evaluation Open
Microbes commonly organize into communities consisting of hundreds of species involved in complex interactions with each other. 16S ribosomal RNA (16S rRNA) amplicon profiling provides snapshots that reveal the phylogenies and abundance pr…
View article: Inferring microbial co-occurrence network from amplicon data: a systematic evaluation
Inferring microbial co-occurrence network from amplicon data: a systematic evaluation Open
Supporting data for the manuscript "Inferring microbial co-occurrence network from amplicon data: a systematic evaluation".
View article: Inferring microbial co-occurrence network from amplicon data: a systematic evaluation
Inferring microbial co-occurrence network from amplicon data: a systematic evaluation Open
Supporting data for the manuscript "Inferring microbial co-occurrence network from amplicon data: a systematic evaluation".
View article: Inferring microbial co-occurrence network from amplicon data: a systematic evaluation
Inferring microbial co-occurrence network from amplicon data: a systematic evaluation Open
Supporting data for the manuscript "Inferring microbial co-occurrence network from amplicon data: a systematic evaluation".
View article: A resource for the comparison and integration of heterogeneous microbiome networks
A resource for the comparison and integration of heterogeneous microbiome networks Open
Naturally occurring microbial communities often comprise thousands of taxa involved in complex networks of interactions. These interactions can be mediated by several mechanisms, including the competition for resources, the exchange of sig…
View article: EZH2 inhibitor GSK343 inhibits sepsis‑induced intestinal disorders
EZH2 inhibitor GSK343 inhibits sepsis‑induced intestinal disorders Open
Enhancer of zeste homolog 2 (EZH2) is positively associated with poor clinical outcomes in a number of aggressive tumors. Recent studies have demonstrated that inhibition of EZH2 also suppressed the inflammatory response during sepsis. The…
View article: Inferring microbial co-occurrence networks from amplicon data: a systematic evaluation
Inferring microbial co-occurrence networks from amplicon data: a systematic evaluation Open
Microbes tend to organize into communities consisting of hundreds of species involved in complex interactions with each other. 16S ribosomal RNA (16S rRNA) amplicon profiling provides snapshots that reveal the phylogenies and abundance pro…
View article: Aberrant ceRNA-mediated regulation of KNG1 contributes to glioblastoma-induced angiogenesis
Aberrant ceRNA-mediated regulation of KNG1 contributes to glioblastoma-induced angiogenesis Open
// Yuan Ren 1, 2 , Nan Ji 3 , Xixiong Kang 4 , Renzhi Wang 2 , Wenbin Ma 2 , Zhenjun Hu 4 , Xingfeng Liu 5 , Yajie Wang 1 1 Laboratory of Clinical Medical Research, Beijing Tiantan Hospital, Capital Medical University, Beijing 10…
View article: A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer
A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer Open
Our method appears to offer promise for the identification of multi-targeted drug candidates that can correct aberrant cellular functions. In particular the computational performance exceeded that of other CMap-based methods, and in vitro …
View article: Visualization of Metabolic Interaction Networks in Microbial Communities Using VisANT 5.0
Visualization of Metabolic Interaction Networks in Microbial Communities Using VisANT 5.0 Open
The complexity of metabolic networks in microbial communities poses an unresolved visualization and interpretation challenge. We address this challenge in the newly expanded version of a software tool for the analysis of biological network…
View article: Additional file 1: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer
Additional file 1: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer Open
is a table listing well-documented mutated genes for breast cancer, prostate cancer and leukemia. (XLS 889 kb)
View article: Additional file 6: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer
Additional file 6: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer Open
is a table listing MAGs for breast cancer and prostate cancer, also has the listing enriched KEGG pathways in breast cancer and prostate cancer. (XLSX 46 kb)
View article: Additional file 13: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer
Additional file 13: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer Open
is a table listing predicted drug candidates for breast and prostate cancer using LINCS dataset. (XLSX 1152 kb)
View article: Additional file 4: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer
Additional file 4: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer Open
shows detailed description of identified drug candidates for breast and prostate cancer. (XLSX 140 kb)
View article: Additional file 5: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer
Additional file 5: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer Open
lists FDA-approved and clinical drugs for breast and prostate cancer. (XLSX 52 kb)
View article: Mutated Pathways as a Guide to Adjuvant Therapy Treatments for Breast Cancer
Mutated Pathways as a Guide to Adjuvant Therapy Treatments for Breast Cancer Open
Adjuvant therapy following breast cancer surgery generally consists of either a course of chemotherapy, if the cancer lacks hormone receptors, or a course of hormonal therapy, otherwise. Here, we report a correlation between adjuvant strat…
View article: COMBREX-DB: an experiment centered database of protein function: knowledge, predictions and knowledge gaps
COMBREX-DB: an experiment centered database of protein function: knowledge, predictions and knowledge gaps Open
The COMBREX database (COMBREX-DB; combrex.bu.edu) is an online repository of information related to (i) experimentally determined protein function, (ii) predicted protein function, (iii) relationships among proteins of unknown function and…
View article: Evaluation and integration of cancer gene classifiers: identification and ranking of plausible drivers
Evaluation and integration of cancer gene classifiers: identification and ranking of plausible drivers Open
The number of mutated genes in cancer cells is far larger than the number of mutations that drive cancer. The difficulty this creates for identifying relevant alterations has stimulated the development of various computational approaches t…