Zhenlei Liu
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View article: Integrated Transcriptome and Metabolome Analysis Provides Insights into the Low-Temperature Response in Sweet Potato (Ipomoea batatas L.)
Integrated Transcriptome and Metabolome Analysis Provides Insights into the Low-Temperature Response in Sweet Potato (Ipomoea batatas L.) Open
Background/Objectives: Sweet potato is a tropical and subtropical crop and its growth and yield are susceptible to low-temperature stress. However, the molecular mechanisms underlying the low temperature stress of sweetpotato are unknown. …
View article: A xyloglucan endotransglucosylase/hydrolase gene, IbXTH16, increases cold tolerance in transgenic sweetpotato
A xyloglucan endotransglucosylase/hydrolase gene, IbXTH16, increases cold tolerance in transgenic sweetpotato Open
Introduction Low temperature is a key environmental factor that threaten sweetpotato growth and development. In-depth studies on the gene functions underlying cold resistance are important for genetic engineering in sweetpotato. Methods Th…
View article: MRI-Based Machine Learning and Radiomics Methods for Assessing Spinal Cord Function in Patients with Mild Cervical Spondylotic Myelopathy
MRI-Based Machine Learning and Radiomics Methods for Assessing Spinal Cord Function in Patients with Mild Cervical Spondylotic Myelopathy Open
(1) Background: Patients with mild cervical spondylotic myelopathy (CSM) who delay surgery risk progression. While PET evaluates spinal cord function, its cost and radiation limit its use. (2) Methods: In this prospective study, patients w…
View article: StMYB66, a R2R3-myb Transcription Factor, Regulates Plant Growth and Anthocyanin Accumulation in Potato (Solanum tuberosum L.)
StMYB66, a R2R3-myb Transcription Factor, Regulates Plant Growth and Anthocyanin Accumulation in Potato (Solanum tuberosum L.) Open
Potatoes are a vital noncereal staple crop that plays a critical role in global food security. Identifying key genes involved in potato growth and development is essential for improving yield and sustainability. In this study, we character…
View article: Effectiveness of Cerebellar Tonsillectomy Treatment for Revision Chiari Malformation Surgery: A Series of 63 Patients
Effectiveness of Cerebellar Tonsillectomy Treatment for Revision Chiari Malformation Surgery: A Series of 63 Patients Open
Dural incision and tonsillar manipulation during the first surgery, spinal cord atrophy prior to revision CTL, and severe intradural adhesions during revision CTL are significant risk factors associated with poor prognosis in revision surg…
View article: Anterior Controllable Antedisplacement Fusion (ACAF) in Revision Surgery for Iatrogenic Cervical Kyphosis: Technical Note and Case Series
Anterior Controllable Antedisplacement Fusion (ACAF) in Revision Surgery for Iatrogenic Cervical Kyphosis: Technical Note and Case Series Open
Background Iatrogenic cervical kyphosis (ICK) often requires complex anterior and posterior correction, which is associated with multiple complications. Consequently, there is a need to investigate alternative treatment approaches that str…
View article: Synthesis and Urea Detection Mechanism of Polyurethane-Urea Copolymer Complexed Nickel(Ni@Nipua)
Synthesis and Urea Detection Mechanism of Polyurethane-Urea Copolymer Complexed Nickel(Ni@Nipua) Open
View article: Structural changes of the multifidus in animal models of intervertebral disk degeneration: a systematic review
Structural changes of the multifidus in animal models of intervertebral disk degeneration: a systematic review Open
Study design Low back pain (LBP) is a widespread clinical symptom affecting nearly all age groups and is a leading cause of disability worldwide. Degenerative changes in the spine and paraspinal tissues primarily contribute to the etiology…
View article: Introducing Angle B: A Novel Quantitative Approach for Sagittal Alignment Reduction in Atlanto-Axial Dislocation Surgery
Introducing Angle B: A Novel Quantitative Approach for Sagittal Alignment Reduction in Atlanto-Axial Dislocation Surgery Open
By introducing angle B and deducing the equation ΔB=ΔCL=D, we have provided an innovative tool for preoperative planning and surgical technique selection for patients with AAD. This equation not only helps surgeons achieve more precise and…
View article: Analysis of Failed Posterior Fossa Decompression and an Effective Revision Surgery in Patients with Basilar Invagination and Atlantoaxial Dislocation
Analysis of Failed Posterior Fossa Decompression and an Effective Revision Surgery in Patients with Basilar Invagination and Atlantoaxial Dislocation Open
Objective The objective of this study was to analyze failed posterior fossa decompression (PFD) in patients with basilar invagination and atlantoaxial dislocation (BI‐AAD). Revision surgery in these patients is challenging and has been rar…
View article: Spinal Adhesive Arachnoidopathy, the Disorder More Than Simply Adhesive Arachnoiditis: A Comprehensive Systematic Review of 510 Cases
Spinal Adhesive Arachnoidopathy, the Disorder More Than Simply Adhesive Arachnoiditis: A Comprehensive Systematic Review of 510 Cases Open
Background Spinal adhesive arachnoidopathy (SAA) is a chronic pathology associated with persistent inflammatory responses in the arachnoid. Adhesive arachnoiditis (AA) is one of the major forms of SAA, with accompanying secondary complicat…
View article: Application of the “Klotski Technique” in Cervical Ossification of the Posterior Longitudinal Ligament With En Bloc Type Dura Ossification
Application of the “Klotski Technique” in Cervical Ossification of the Posterior Longitudinal Ligament With En Bloc Type Dura Ossification Open
Objective: The anterior controllable antedisplacement and fusion (ACAF) technique is a new procedure for the treatment of cervical ossification of the posterior longitudinal ligament (OPLL) that requires management of the disc adjacent to …
View article: Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases
Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases Open
OBJECTIVE This study aimed to investigate the differences in clinical features, diagnostic examination, treatment, and pathological results between adult-onset and pediatric-onset tethered cord syndrome (TCS). METHODS The authors searched …
View article: Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development - A Subtype of Craniovertebral Junction Malformation?
Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development - A Subtype of Craniovertebral Junction Malformation? Open
Objective: To investigate the developmental defects caused by knockdown of best1 gene in zebrafish as a model for a subtype of craniovertebral junction (CVJ) malformation.Methods: Two antisense morpholinos (MOs) were designed targeting zeb…
View article: Role of Preoperative Albumin Quotient in Surgical Planning for Posttraumatic Syringomyelia: A Comparative Cohort Study
Role of Preoperative Albumin Quotient in Surgical Planning for Posttraumatic Syringomyelia: A Comparative Cohort Study Open
Objective: Surgical procedures for patients with posttraumatic syringomyelia (PTS) remain controversial. Until now, there have been no effective quantitative evaluation methods to assist in selecting appropriate surgical plans before surge…
View article: The Natural History of Chiari Malformation-Syringomyelia: Evidence of Bidirectional Flow of Central Canal Fluid within the Spinal Cord
The Natural History of Chiari Malformation-Syringomyelia: Evidence of Bidirectional Flow of Central Canal Fluid within the Spinal Cord Open
View article: Genome-Wide Identification and Expression Analysis of the MADS Gene Family in Tulips (Tulipa gesneriana)
Genome-Wide Identification and Expression Analysis of the MADS Gene Family in Tulips (Tulipa gesneriana) Open
To investigate the cold response mechanism and low temperature regulation of flowering in tulips, this study identified 32 MADS-box transcription factor family members in tulips based on full-length transcriptome sequencing, named TgMADS1-…
View article: Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma
Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma Open
Objective: Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, liquid biopsy of primary intramedullary astrocytoma was rarely reported. Given the distinct genomic…
View article: Intra-articular Distraction Versus Decompression to Treat Basilar Invagination Without Atlantoaxial Dislocation: A Retrospective Cohort Study of 54 Patients
Intra-articular Distraction Versus Decompression to Treat Basilar Invagination Without Atlantoaxial Dislocation: A Retrospective Cohort Study of 54 Patients Open
Objective: The surgical management of basilar invagination without atlantoaxial dislocation (type B basilar invagination) remains controversial. Hence, we have reported the use of posterior intra-articular C1–2 facet distraction, fixation,…
View article: Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease
Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease Open
Objective: To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF combined with anterolateral screw fixation (OLIF-AF), and OLIF combined with percutaneous pedicle screw fixation (OLIF-PF) in the treatment of single-level…
View article: Predicting deep surgical site infection in patients receiving open posterior instrumented thoracolumbar surgery: A-DOUBLE-SSI risk score – a large retrospective multicenter cohort study in China
Predicting deep surgical site infection in patients receiving open posterior instrumented thoracolumbar surgery: A-DOUBLE-SSI risk score – a large retrospective multicenter cohort study in China Open
Background: To develop a practical prediction model to predict the risk of deep surgical site infection (SSI) in patients receiving open posterior instrumented thoracolumbar surgery. Methods: Data of 3419 patients in four hospitals from 1 …
View article: Relationship Between Syrinx Resolution and Cervical Sagittal Realignment Following Decompression Surgery for Chiari I Malformation Related Syringomyelia Based on Configuration Phenotypes
Relationship Between Syrinx Resolution and Cervical Sagittal Realignment Following Decompression Surgery for Chiari I Malformation Related Syringomyelia Based on Configuration Phenotypes Open
Objective: Combined with different configuration types of syringomyelia, to analyze the correlation between syrinx resolution and changes in cervical sagittal alignment following Foramen magnum and Magendie dredging (FMMD) for syringomyeli…
View article: Neurological deterioration after posterior fossa decompression for adult syringomyelia: Proposal for a summarized treatment algorithm
Neurological deterioration after posterior fossa decompression for adult syringomyelia: Proposal for a summarized treatment algorithm Open
Background Patients with syringomyelia who present with new neurological symptoms after posterior fossa decompression (PFD) are not uncommon. However, systematic reports on different pathologies are few in the literature. Objective The pur…
View article: How to locate the dural defect in a spinal extradural meningeal cyst: a literature review
How to locate the dural defect in a spinal extradural meningeal cyst: a literature review Open
Spinal extradural meningeal cysts (SEMCs) are rare lesions of the spinal canal. Although closure of the dural defect can achieve satisfactory therapeutic effects, locating the fistula is difficult. This review summarizes the methods for lo…
View article: Spinal Obstruction-Related vs. Craniocervical Junction-Related Syringomyelia: A Comparative Study
Spinal Obstruction-Related vs. Craniocervical Junction-Related Syringomyelia: A Comparative Study Open
Background No prior reports have focused on spinal cord injury (SCI) characteristics or inflammation after destruction of the blood–spinal cord barrier by syringomyelia. This study aimed to determine the differences in syringomyelia-relate…
View article: Dural repair with fat patch for idiopathic spinal cord herniation: operative technique and a review of seven cases
Dural repair with fat patch for idiopathic spinal cord herniation: operative technique and a review of seven cases Open
Surgical treatment using fat patch is an effective strategy for the ventral dural defect repair of ISCH.
View article: Treatment of Upper Lumbar Disc Herniation with a Transforaminal Endoscopic Technique
Treatment of Upper Lumbar Disc Herniation with a Transforaminal Endoscopic Technique Open
Background To investigate the clinical efficacy of percutaneous endoscopic transforaminal discectomy (PETD) in the treatment of upper lumbar disc herniation (LDH). Methods Twenty-two patients, 14 males and 8 females with ages ranging from …
View article: The sweet potato transcription factor IbbHLH33 enhances chilling tolerance in transgenic tobacco
The sweet potato transcription factor IbbHLH33 enhances chilling tolerance in transgenic tobacco Open
Chilling is an important abiotic stress in plants. Sweet potato is sensitive to cold damage due to its tropical origin. In this study, we identified a basic helix-loop-helix (bHLH) gene, IbbHLH33, from our cold-tolerance-related transcript…
View article: Reconstruction of the Cervical Lateral Mass Using 3-Dimensional-Printed Prostheses
Reconstruction of the Cervical Lateral Mass Using 3-Dimensional-Printed Prostheses Open
Objective: This study aimed to investigate the outcome of using 3-dimensional (3D)-printed prostheses to reconstruct a cervical lateral mass to maintain cervical stability.Methods: We retrospectively analyzed data of 7 patients who underwe…
View article: A 540° posterior-anterior-posterior approach for 360° fused rigid severe cervical kyphosis: patient series
A 540° posterior-anterior-posterior approach for 360° fused rigid severe cervical kyphosis: patient series Open
BACKGROUND Treatment of severe rigid 360° fused cervical kyphosis (CK) is challenging and often requires a combined approach for ankylosis release, establishment of sagittal balance, and fixation with fusion. OBSERVATIONS Four patients wit…