Zhi‐Jie Hong
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View article: Multi-cohort analysis unveils novel microbial targets for the treatment of hyperuricemia and gout
Multi-cohort analysis unveils novel microbial targets for the treatment of hyperuricemia and gout Open
The gut microbiota plays a crucial role in the development of hyperuricemia (HUA) and gout. However, the variability in study designs and analytical methods has led to inconsistent conclusions across different studies. Here, we conducted a…
View article: Therapeutic effect of fecal microbiota transplantation on hyperuricemia mice by improving gut microbiota
Therapeutic effect of fecal microbiota transplantation on hyperuricemia mice by improving gut microbiota Open
Objective The primary objective of this study was to assess the impact of fecal microbiota transplantation (FMT) on serum biochemical parameters, renal injury, and gut microbiota in hyperuricemia (HUA) mice. Methods Six-week-old male C57BL…
View article: The predict value of lymph node status pre-operation by ultrasound, mammography and MRI in early breast cancer
The predict value of lymph node status pre-operation by ultrasound, mammography and MRI in early breast cancer Open
Combined ultrasound and MRI evaluation, when integrated with tumor grade, size, and HER-2 status, offers a reliable approach for preoperative prediction of lymph node metastasis. This method may reduce unnecessary axillary surgery and its …
View article: Unexpected contralateral axillary lymph node metastasis without ipsilateral involvement in triple-negative breast cancer: A case report and review of literature
Unexpected contralateral axillary lymph node metastasis without ipsilateral involvement in triple-negative breast cancer: A case report and review of literature Open
BACKGROUND Breast cancer is a leading cause of cancer-related mortality among women worldwide, with invasive ductal carcinoma (IDC) being the most prevalent subtype. Lymph node metastasis is the primary prognostic indicator, typically eval…
View article: Ductal Carcinoma In Situ of the Breast in Sclerosing Adenosis Mimicking Microinvasive Ductal Carcinoma: A Rare Case Report
Ductal Carcinoma In Situ of the Breast in Sclerosing Adenosis Mimicking Microinvasive Ductal Carcinoma: A Rare Case Report Open
Sclerosing adenosis (SA) is a subtype of adenosis characterized by proliferative adenosis and stromal sclerosis with distortion of the terminal ductal lobular unit. Although SA is the most prevalent benign breast condition among middle‐age…
View article: Hub metastatic gene signature and risk score of breast cancer patients with small tumor sizes using WGCNA
Hub metastatic gene signature and risk score of breast cancer patients with small tumor sizes using WGCNA Open
Background Breast cancer (BC) is the most common cancer in women and accounts for approximately 15% of all cancer deaths among women globally. The underlying mechanism of BC patients with small tumor size and developing distant metastasis …
View article: Diagnostic laparoscopy with indocyanine green fluorescence test for the evaluation of intestinal perfusion in abdominal blunt injury: a case report
Diagnostic laparoscopy with indocyanine green fluorescence test for the evaluation of intestinal perfusion in abdominal blunt injury: a case report Open
Our case underscores the efficacy of ICG fluorescence testing in assessing bowel viability and guiding surgical strategies in trauma patients with mesenteric hematoma. By facilitating real-time visualization of blood perfusion, ICG testing…
View article: Comprehensive Analysis of Gamma-Aminobutyric Acid Receptor Subunit Pi (Gabrp) Expression and its Prognostic Significance in Breast Cancer
Comprehensive Analysis of Gamma-Aminobutyric Acid Receptor Subunit Pi (Gabrp) Expression and its Prognostic Significance in Breast Cancer Open
View article: Diffuse Allergic Reaction to Patent Blue Dye for Sentinel Node Biopsy in Breast Cancer: A Case Report
Diffuse Allergic Reaction to Patent Blue Dye for Sentinel Node Biopsy in Breast Cancer: A Case Report Open
We present the case of a 59-year-old Taiwanese female who is married and retired, and was diagnosed with invasive ductal carcinoma in her right breast at stage cT1cN0 (Stage IA). She visited us for further treatment and underwent breast-co…
View article: The prognostic factors on survival outcome following locoregional recurrence after mastectomy for breast cancer – A retrospective study in single medical centre in lower incidence and young age area
The prognostic factors on survival outcome following locoregional recurrence after mastectomy for breast cancer – A retrospective study in single medical centre in lower incidence and young age area Open
Background. Women of breast cancer with locoregional recurrence is a ‘high risk’ subgroup with respect to systemic recurrence and mortality after mastectomy. It is important to early identify the prognostic factors on survival outcome foll…
View article: The Risk of Breast Cancer between Western and Mediterranean Dietary Patterns
The Risk of Breast Cancer between Western and Mediterranean Dietary Patterns Open
Breast cancer is a significant public health problem globally and prevention strategies have become of great interest as its incidence rises. Exploring the connection between dietary patterns and the reduction of breast cancer risk is cons…
View article: Invasive breast carcinoma with osteoclast-like stromal giant cells: A case report
Invasive breast carcinoma with osteoclast-like stromal giant cells: A case report Open
As a rare morphology of breast cancer, breast carcinoma with OGC occurs most often in relatively young women, has less lymph node involvement, and its occurrence is not race-dependent.
View article: Advancing breast cancer subtyping: optimizing immunohistochemical staining classification with insights from real-world Taiwanese data.
Advancing breast cancer subtyping: optimizing immunohistochemical staining classification with insights from real-world Taiwanese data. Open
Gene expression signatures provide valuable information to guide postoperative treatment in breast cancer (BC) patients. However, genetic tests are prohibitively expensive for the majority of BC patients. Immunohistochemical staining (IHC)…
View article: The influence of early selenium supplementation on trauma patients: A propensity-matched analysis
The influence of early selenium supplementation on trauma patients: A propensity-matched analysis Open
Introduction Oxidative stress is involved in numerous inflammatory diseases, including trauma. Micronutrients, such as selenium (Se), which contribute to antioxidant defense, exhibit low plasma levels during critical illness. This study ai…
View article: Comparison of Long-Term Pneumonia Risk between Spleen Injury and Non-Spleen Injury after Total Splenectomy—A Population-Based Study
Comparison of Long-Term Pneumonia Risk between Spleen Injury and Non-Spleen Injury after Total Splenectomy—A Population-Based Study Open
Patients who undergo splenectomy are at a high risk of infection. We aimed to investigate the rate of pneumonia in patients who underwent splenectomy, specifically comparing those who had splenectomy due to spleen injury and those who had …
View article: Alpha-Lipoic Acid Inhibits Spontaneous Diabetes and Autoimmune Recurrence in Non-Obese Diabetic Mice by Enhancing Differentiation of Regulatory T Cells and Showed Potential for Use in Cell Therapies for the Treatment of Type 1 Diabetes
Alpha-Lipoic Acid Inhibits Spontaneous Diabetes and Autoimmune Recurrence in Non-Obese Diabetic Mice by Enhancing Differentiation of Regulatory T Cells and Showed Potential for Use in Cell Therapies for the Treatment of Type 1 Diabetes Open
Type 1 diabetes (T1D) is caused by the destruction of β cells in pancreatic islets by autoimmune T cells. Islet transplantation has been established as an effective treatment for T1D. However, the survival of islet grafts is often disrupte…
View article: The impact of frailty on breast cancer outcomes: evidence from analysis of the Nationwide Inpatient Sample, 2005-2018.
The impact of frailty on breast cancer outcomes: evidence from analysis of the Nationwide Inpatient Sample, 2005-2018. Open
The aims of the present study were to examine whether and how frailty impacts the outcomes of breast cancer. Data of women with breast cancer hospitalized during 2005 and 2018 were extracted from the US Nationwide Inpatient Sample (NIS) da…
View article: Survival outcomes in elderly Taiwanese women according to breast cancer subtype and lymph node status: A single-center retrospective study
Survival outcomes in elderly Taiwanese women according to breast cancer subtype and lymph node status: A single-center retrospective study Open
This study aimed to determine the rates of overall survival and recurrence-free survival among elderly Taiwanese women (>65 years old) according to breast cancer subtype and lymph node status. We identified 554 eligible patients who were >…
View article: Procoagulant and Antimicrobial Effects of Chitosan in Wound Healing
Procoagulant and Antimicrobial Effects of Chitosan in Wound Healing Open
Chitosan, a polysaccharide derived from chitin, has excellent wound healing properties, including intrinsic antimicrobial and hemostatic activities. This study investigated the effectiveness of chitosan dressing and compared it with that o…
View article: Valproic Acid Suppresses Autoimmune Recurrence and Allograft Rejection in Islet Transplantation through Induction of the Differentiation of Regulatory T Cells and Can Be Used in Cell Therapy for Type 1 Diabetes
Valproic Acid Suppresses Autoimmune Recurrence and Allograft Rejection in Islet Transplantation through Induction of the Differentiation of Regulatory T Cells and Can Be Used in Cell Therapy for Type 1 Diabetes Open
Type 1 diabetes mellitus (T1D) results from the destruction of insulin-producing β cells in the islet of the pancreas by lymphocytes. Non-obese diabetic (NOD) mouse is an animal model frequently used for this disease. It has been considere…
View article: Survival Benefits Associated with Surgery in Patients with Metastatic Breast Cancer by Breast Cancer Subtype
Survival Benefits Associated with Surgery in Patients with Metastatic Breast Cancer by Breast Cancer Subtype Open
Background: Two randomized trials have examined the role of local therapy on survival in the stage IV setting of breast cancer, largely suggesting no benefit. However, the effect of surgery for stage IV disease amongst various breast cance…
View article: Open-chest versus closed-chest cardiopulmonary resuscitation in trauma patients with signs of life upon hospital arrival: a retrospective multicenter study
Open-chest versus closed-chest cardiopulmonary resuscitation in trauma patients with signs of life upon hospital arrival: a retrospective multicenter study Open
View article: Risk for Irritable Bowel Syndrome in Patients with Helicobacter Pylori Infection: A Nationwide Population-Based Study Cohort Study in Taiwan
Risk for Irritable Bowel Syndrome in Patients with Helicobacter Pylori Infection: A Nationwide Population-Based Study Cohort Study in Taiwan Open
Background: The association between Helicobacter pylori (H. pylori) infection and the risk of developing irritable bowel syndrome (IBS) has yet to be investigated; thus, we conducted this nationwide cohort study to examine the association …
View article: Biological Effects of Chitosan-Based Dressing on Hemostasis Mechanism
Biological Effects of Chitosan-Based Dressing on Hemostasis Mechanism Open
There have been numerous recent advances in wound care management. Nevertheless, the assessment of hemostatic dressing is essential to enable surgeons and other physicians and healthcare professionals to make the correct decisions regardin…
View article: Evaluation of Chitosan-based Dressings in a Swine Model of Artery-Injury-Related Shock
Evaluation of Chitosan-based Dressings in a Swine Model of Artery-Injury-Related Shock Open
Uncontrolled haemorrhage shock is the highest treatment priority for military trauma surgeons. Injuries to the torso area remain the greatest treatment challenge, since external dressings and compression cannot be used here. Bleeding contr…
View article: The Effect of Using Multimedia Education in Women’s Breast Cancer Screening Health Education Program
The Effect of Using Multimedia Education in Women’s Breast Cancer Screening Health Education Program Open
Breast cancer is an important disease that threatens the lives of women. The majority of breast screening health education is printed promotional material, which is ineffective in enhancing women’s knowledge on breast screening in Ta…
View article: Prognostic role of lymphovascular invasion and lymph node status among breast cancer subtypes
Prognostic role of lymphovascular invasion and lymph node status among breast cancer subtypes Open
Context: Breast cancer subtype (BCS) and lymphovascular invasion (LVI) have both been independently demonstrated as prognostic factors.Aims: The objective of this investigation was to evaluate the prognostic power of LVI among BCSs.Setting…
View article: Acute Mesenteric Venous Thrombosis
Acute Mesenteric Venous Thrombosis Open
View article: Outcomes of patients with blunt chest trauma encountered at emergency department and possible risk factors affecting mortality
Outcomes of patients with blunt chest trauma encountered at emergency department and possible risk factors affecting mortality Open
Background: Blunt chest trauma is associated with a high risk of mortality. Respiratory complications may necessitate prolonged ventilation and result in death. The present study aimed to investigate possible signs of trauma and the progno…
View article: The evolution of computed tomography from organ-selective to whole-body scanning in managing unconscious patients with multiple trauma
The evolution of computed tomography from organ-selective to whole-body scanning in managing unconscious patients with multiple trauma Open
We aimed to evaluate the benefit of whole-body computed tomography (WBCT) scanning for unconscious adult patients suffering from high-energy multiple trauma compared with the conventional stepwise approach of organ-selective CT.Totally, 14…