Zhenyu Jiao
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View article: An Opto‐Bio‐Hydrodynamic Platform for Instructing Cardiac Left‐Right Asymmetry Development
An Opto‐Bio‐Hydrodynamic Platform for Instructing Cardiac Left‐Right Asymmetry Development Open
The spatiotemporal regulation of ciliary dynamics within the left‐right organizer (LRO) governs cardiac laterality establishment through biomechanical signaling gradients. While targeted restoration of aberrant ciliary motion can theoretic…
View article: Metformin protects against insulin resistance induced by high uric acid in cardiomyocytes via AMPK signalling pathways in vitro and in vivo
Metformin protects against insulin resistance induced by high uric acid in cardiomyocytes via AMPK signalling pathways in vitro and in vivo Open
High uric acid (HUA) is associated with insulin resistance (IR) in cardiomyocytes. We investigated whether metformin protects against HUA‐induced IR in cardiomyocytes. We exposed primary cardiomyocytes to HUA, and cellular glucose uptake w…
View article: Metformin protects against insulin resistance induced by high uric acid in cardiomyocytes via AMPK signaling pathways in vitro and in vivo
Metformin protects against insulin resistance induced by high uric acid in cardiomyocytes via AMPK signaling pathways in vitro and in vivo Open
BackgroundHigh uric acid (HUA) is associated with insulin resistance and abnormal glucose metabolism in cardiomyocytes. Metformin is a recognized agonist of AMP-activated protein kinase (AMPK) and an antidiabetic drug widely used for type …
View article: Metformin Protects Against Insulin Resistance Induced by High Uric Acid in Cardiomyocytes via AMPK Signaling Pathways in Vitro and in Vivo
Metformin Protects Against Insulin Resistance Induced by High Uric Acid in Cardiomyocytes via AMPK Signaling Pathways in Vitro and in Vivo Open
High uric acid (HUA) is associated with insulin resistance and abnormal glucose metabolism in cardiomyocytes. Metformin is a recognized agonist of AMP-activated protein kinase (AMPK) and an antidiabetic drug widely used for type 2 diabetes…
View article: Metformin protects against insulin resistance induced by high uric acid in cardiomyocytes via AMPK signaling pathways in vitro and in vivo
Metformin protects against insulin resistance induced by high uric acid in cardiomyocytes via AMPK signaling pathways in vitro and in vivo Open
High uric acid (HUA) is associated with insulin resistance and abnormal glucose metabolism in cardiomyocytes. Metformin is a recognized agonist of AMP-activated protein kinase (AMPK) and an antidiabetic drug widely used for type 2 diabetes…
View article: Effect of Platelet Count on Prognostic Value in Patients with Chronic Heart Failure
Effect of Platelet Count on Prognostic Value in Patients with Chronic Heart Failure Open
Background: The prognostic value of platelet count in chronic heart failure (CHF) is not clearly established. The present study aimed to assesse the independent prognostic value of platelet count in patients with CHF. Methods: From Januay …
View article: Differentiating origins of outflow tract ventricular arrhythmias: a comparison of three different electrocardiographic algorithms
Differentiating origins of outflow tract ventricular arrhythmias: a comparison of three different electrocardiographic algorithms Open
Our objective is to evaluate the accuracy of three algorithms in differentiating the origins of outflow tract ventricular arrhythmias (OTVAs). This study involved 110 consecutive patients with OTVAs for whom a standard 12-lead surface elec…
View article: Correlation of triglycerides with myocardial infarction and analysis of risk factors for myocardial infarction in patients with elevated triglyceride
Correlation of triglycerides with myocardial infarction and analysis of risk factors for myocardial infarction in patients with elevated triglyceride Open
In the study population of the Kailuan region, elevated fasting TG increases the risk of MI, particularly in populations with an age of ≥65 years old, BMI >25 kg/m2, FBG ≥6.1 mmol/L and HDL-C <1.5 mmol/L.
View article: Clinical analysis of acute myocardial infarction caused by coronary embolism
Clinical analysis of acute myocardial infarction caused by coronary embolism Open
The status for AMI due to coronary artery embolism usually expresses embolic material originating from the left heart chambers. Rheumatic heart disease and atrial fibrillation are the common reasons for coronary artery embolism. Coronary a…
View article: Masquerading bundle branch block as a presenting manifestation of complete atrioventricular block that caused syncope
Masquerading bundle branch block as a presenting manifestation of complete atrioventricular block that caused syncope Open
A 59-year-old male patient was admitted with the main complaints of stuffiness and shortness of breath. An ECG from precordial leads on admission showed masquerading bundle branch block. Syncope frequently occurred after admission. During …
View article: Differentiating origins of outflow tract ventricular arrhythmias: a comparison of three different electrocardiographic algorithms
Differentiating origins of outflow tract ventricular arrhythmias: a comparison of three different electrocardiographic algorithms Open
Our objective is to evaluate the accuracy of three algorithms in differentiating the origins of outflow tract ventricular arrhythmias (OTVAs). This study involved 110 consecutive patients with OTVAs for whom a standard 12-lead surface elec…