Zhenzhen Huang
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View article: O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review)
O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review) Open
Sepsis is a life‑threatening condition triggered by dysregulated host immune responses, involving complex interactions among immune cell dysfunction, metabolic reprogramming and impaired autophagy. As a dynamic post‑translational modificat…
View article: Mechanism and Multilayer Perceptron prediction model of the removal of α-terpineol, terpinen-4-ol and carvone from pasteurized citrus juices by β-cyclodextrin encapsulation
Mechanism and Multilayer Perceptron prediction model of the removal of α-terpineol, terpinen-4-ol and carvone from pasteurized citrus juices by β-cyclodextrin encapsulation Open
This study revealed the mechanism of improvement in sensory evaluation of citrus juices after pasteurization by the natural cyclodextrin ( β -CD), and developed a prediction model for encapsulation based on conventional physicochemical ind…
View article: Phosphoenolpyruvate carboxykinase 2 Could Be Used For distiguishment Of Hepatoblastoma And Affecting Ferroptosis
Phosphoenolpyruvate carboxykinase 2 Could Be Used For distiguishment Of Hepatoblastoma And Affecting Ferroptosis Open
Hepatoblastoma (HB) is the most common malignant liver tumor in children, with low cure rates due to the lack of accurate predictive tar-gets. Phosphoenolpyruvate carboxykinase 2 (PCK2) has been implicated in various tumors and may regulat…
View article: Exploration and Practice of Ideological and Political Teaching Reform in Investment Course
Exploration and Practice of Ideological and Political Teaching Reform in Investment Course Open
Deeply exploring the ideological and political elements of various courses in universities and integrating ideological and political education into the entire teaching process is the development trend of ideological and political education…
View article: Exploring Students’ Learning Experiences Under the China–Korea Cooperative Teaching Model: A Positive Psychology Perspective
Exploring Students’ Learning Experiences Under the China–Korea Cooperative Teaching Model: A Positive Psychology Perspective Open
Based on the theory of learning experiences and the Positive Emotion, Engagement, Relationships, Meaning, and Accomplishment (PERMA) model, this research aims to interpret the learning experiences of students majoring in Animation under th…
View article: Conversion of Limonene by Penicillium Digitatum Dsm62840 to Produce Α-Terpineol as a Key Enzyme
Conversion of Limonene by Penicillium Digitatum Dsm62840 to Produce Α-Terpineol as a Key Enzyme Open
View article: YTHDF1 in periaqueductal gray inhibitory neurons contributes to morphine withdrawal responses in mice
YTHDF1 in periaqueductal gray inhibitory neurons contributes to morphine withdrawal responses in mice Open
YTHDF1 originating from Sst-expressing neurons in the vlPAG is crucial for the modulation of morphine withdrawal responses, and the underlying mechanism might be related to the regulation of the expression and phosphorylation of NF-κB.
View article: Copper ion/gallic acid MOFs-laden adhesive pomelo peel sponge effectively treats biofilm-infected skin wounds and improves healing quality
Copper ion/gallic acid MOFs-laden adhesive pomelo peel sponge effectively treats biofilm-infected skin wounds and improves healing quality Open
View article: Prescription analgesic medication use among osteoarthritis patients
Prescription analgesic medication use among osteoarthritis patients Open
Objective Pharmacotherapy is the most common strategies to reduce pain for osteoarthritis (OA) patients. To analyze the trend and pattern of prescription analgesic medication use in American OA patients. Besides, our study also tried to fi…
View article: Super‐Elastic Carbonized Mushroom Aerogel for Management of Uncontrolled Hemorrhage
Super‐Elastic Carbonized Mushroom Aerogel for Management of Uncontrolled Hemorrhage Open
Uncontrolled hemorrhage is still the most common cause of potentially preventable death after trauma in prehospital settings. However, there rarely are hemostatic materials that can achieve safely and efficiently rapid hemostasis simultane…
View article: Preclinical evaluation of ISH0339, a tetravalent broadly neutralizing bispecific antibody against SARS-CoV-2 with long-term protection
Preclinical evaluation of ISH0339, a tetravalent broadly neutralizing bispecific antibody against SARS-CoV-2 with long-term protection Open
Background: Ending the global COVID-19 pandemic requires efficacious therapies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nevertheless, the emerging Omicron sublineages largely escaped the neutralization of curre…
View article: A modified apical resection model with high accuracy and reproducibility in neonatal mouse and rat hearts
A modified apical resection model with high accuracy and reproducibility in neonatal mouse and rat hearts Open
View article: Analysis of the typing of adenovirus and its clinical characteristics in children with acute respiratory tract infection
Analysis of the typing of adenovirus and its clinical characteristics in children with acute respiratory tract infection Open
Background The purpose of this study was to investigate the typing of adenovirus (AdV) infection in children hospitalized with acute respiratory tract infection (ARTI) and its clinical characteristics. Methods Samples from 7832 hospitalize…
View article: Copper Ion/Gallic Acid Mofs-Laden Adhesive Pomelo Peel Sponge Effectively Treats Biofilm-Infected Skin Wounds and Improves Healing Quality
Copper Ion/Gallic Acid Mofs-Laden Adhesive Pomelo Peel Sponge Effectively Treats Biofilm-Infected Skin Wounds and Improves Healing Quality Open
View article: Enhanced Adsorption of Sulfonamides by Attapulgite-Doped Biochar Prepared with Calcination
Enhanced Adsorption of Sulfonamides by Attapulgite-Doped Biochar Prepared with Calcination Open
The extensive use of sulfonamides seriously threatens the safety and stability of the ecological environment. Developing green inexpensive and effective adsorbents is critically needed for the elimination of sulfonamides from wastewater. T…
View article: Preclinical evaluation of IAP0971, a novel immunocytokine that binds specifically to PD1 and fuses IL15/IL15R<b>α</b> complex
Preclinical evaluation of IAP0971, a novel immunocytokine that binds specifically to PD1 and fuses IL15/IL15R<b>α</b> complex Open
Background Currently, cytokine therapy for cancer has demonstrated efficacy in certain diseases but is generally accompanied by severe toxicity. The field of antibody-cytokine fusion proteins (immunocytokines) arose to target these effecto…
View article: Natural plant compounds in synthesis and luminescence modulation of metal nanoclusters: Toward sustainable nanoprobes for sensing and bioimaging
Natural plant compounds in synthesis and luminescence modulation of metal nanoclusters: Toward sustainable nanoprobes for sensing and bioimaging Open
Luminescent metal nanoclusters (LMNCs) with a diameter of less than 3 nm have fascinated scientific community in the past two decades for facile synthesis, ultra-small size, and tunable optical properties. For the synthesis and luminescenc…
View article: Translocation of gasdermin D induced mitochondrial injury and mitophagy mediated quality control in lipopolysaccharide related cardiomyocyte injury
Translocation of gasdermin D induced mitochondrial injury and mitophagy mediated quality control in lipopolysaccharide related cardiomyocyte injury Open
Backgrounds Inflammation underlies the mechanism of different kinds of heart disease. Cytoplasmic membrane localized N‐terminal fragment of gasdermin‐D (GSDMD‐N) could induce inflammatory injury to cardiomyocyte. However, effects and dynam…
View article: Role of the Gut Microbiota in Glucose Metabolism During Heart Failure
Role of the Gut Microbiota in Glucose Metabolism During Heart Failure Open
Background Blood glucose disorders are prevalent in heart failure, while the influence of the gut microbiota on this process remains unclear. Here, we used heart failure model mice and fecal microbiota transplantation (FMT) mice to evaluat…
View article: Role of Mitophagy-based TLR9 Signal Pathway in Neonatal Ventilator-induced Lung Injury
Role of Mitophagy-based TLR9 Signal Pathway in Neonatal Ventilator-induced Lung Injury Open
The study focused on the role of mitophagy in neonatal ventilator-induced lung injury (VILI). Immunoassays were used to study the TLR9 signaling pathway of neonatal VILI, expected to provide a feasible solution for neonatal VILI. The mice …
View article: Mn, B, N co-doped graphene quantum dots for fluorescence sensing and biological imaging
Mn, B, N co-doped graphene quantum dots for fluorescence sensing and biological imaging Open
The fluorescent and quantum yield (QY) of graphene quantum dots has been improved in recent years by doped atoms, which have good application prospects in fluorescence sensors and biological imaging. Here, a one-step hydrothermal synthesis…
View article: CCDC 1903214: Experimental Crystal Structure Determination
CCDC 1903214: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Orchard Energy Management to Improve Fruit Quality Based on the Internet of Things
Orchard Energy Management to Improve Fruit Quality Based on the Internet of Things Open
The crop growth is an energy conversion process, and energy management has an important impact on the quality and yield of crop products. As IoT (the Internet of Things) is widely used in agriculture, for example, orchard IoT is often used…
View article: Introduction of Ancient Chinese Poetry into Acid-Base Titration in Analytical Chemistry Course
Introduction of Ancient Chinese Poetry into Acid-Base Titration in Analytical Chemistry Course Open
By taking acid-base titration as an example, Chinese poetry and other cultural works were introduced into the introduction, exercises, and ideological and political education of the introduction to acid-base titration, pH indicators, and t…
View article: Au Nanoflowers for Catalyzing and In Situ Surface-Enhanced Raman Spectroscopy Monitoring of the Dimerization of <i>p</i>-Aminothiophenol
Au Nanoflowers for Catalyzing and In Situ Surface-Enhanced Raman Spectroscopy Monitoring of the Dimerization of <i>p</i>-Aminothiophenol Open
In this work, we demonstrated a facile approach for fabrication of Au nanoflowers (Au NFs) using an amino-containing organosilane, 3-aminopropyltriethoxysilane (APTES), as a shape-directing agent. In this approach, the morphology of the Au…
View article: Actinoplanes aureus sp. nov., a novel protease-producing actinobacterium isolated from soil
Actinoplanes aureus sp. nov., a novel protease-producing actinobacterium isolated from soil Open
A novel protease-producing actinobacterium, designated strain NEAU-A11T, was isolated from soil collected from Aohan banner, Chifeng, Inner Mongolia Autonomous Region, China, and characterised using a polyphasic approach. On the…
View article: Sensitive Cu2+ detection by reversible on-off fluorescence using Eu3+ complexes in SiO2, in chitosan/polyethylene oxide nanofibers
Sensitive Cu2+ detection by reversible on-off fluorescence using Eu3+ complexes in SiO2, in chitosan/polyethylene oxide nanofibers Open
View article: Key Points of Policing Work at Underground Station of High Speed Railway in Hainan International Tourism Island
Key Points of Policing Work at Underground Station of High Speed Railway in Hainan International Tourism Island Open
The forest coverage rate of Hainan Island is more than 60%, and the forest is an important ecological support for Hainan to build an international tourism island. Aircraft and high-speed railway are the main means of carrying tourists. The…
View article: Electronic Media Device Usage and Its Associations With BMI and Obesity in a Rapidly Developing City in South China
Electronic Media Device Usage and Its Associations With BMI and Obesity in a Rapidly Developing City in South China Open
Objective: This study aimed to evaluate the television (TV) viewing and computer and mobile phone usage duration in a community sample of Chinese adults and examine their associations with BMI and obesity. Methods: We conducted a community…
View article: Mn, B, N Co-Doped Graphene Quantum Dots for Fluorescence Sensing and Biological Imaging
Mn, B, N Co-Doped Graphene Quantum Dots for Fluorescence Sensing and Biological Imaging Open