Zhenzhen Zhang
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View article: A single-cell transcriptomic study of milk cells from dairy cows with divergent lactation performance
A single-cell transcriptomic study of milk cells from dairy cows with divergent lactation performance Open
View article: New molecular diagnostic targets for Avibacterium paragallinarum and a set of single-plex and multiplex qPCR methods for the rapid differential diagnosis of Mycoplasma gallisepticum, Mycoplasma synoviae, and Avibacterium paragallinarum
New molecular diagnostic targets for Avibacterium paragallinarum and a set of single-plex and multiplex qPCR methods for the rapid differential diagnosis of Mycoplasma gallisepticum, Mycoplasma synoviae, and Avibacterium paragallinarum Open
View article: RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma
RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma Open
The identification of predictive markers to determine the premetastatic phase before metastasis is critical for developing effective strategies for early detection and prevention. By applying the dynamic network biomarker (DNB) approach to…
View article: Polyploidy‐mediated variations in glutamate receptor proteins linked to <i>Fusarium</i> wilt resistance in upland cotton
Polyploidy‐mediated variations in glutamate receptor proteins linked to <i>Fusarium</i> wilt resistance in upland cotton Open
SUMMARY Cotton production in the US faces a serious threat from Fusarium oxysporum f. sp. vasinfectum race 4 (FOV4), a soil‐borne fungus causing Fusarium wilt by infecting the roots and vascular system of susceptible cotton, leading to rap…
View article: Spatial-Temporal Heterogeneity of the Equity of Ecosystem Services and its Drivers Across Scales
Spatial-Temporal Heterogeneity of the Equity of Ecosystem Services and its Drivers Across Scales Open
View article: Transcriptome analysis of mammary epithelial cell between Sewa sheep and East FriEsian sheep from different localities
Transcriptome analysis of mammary epithelial cell between Sewa sheep and East FriEsian sheep from different localities Open
View article: AADMM based shared energy storage planning for resilience improvement of renewable energy stations
AADMM based shared energy storage planning for resilience improvement of renewable energy stations Open
The exponential proliferation of renewable energy has resulted in a significant mismatch between power supply and demand, especially during extreme events. This incongruity presents challenges in efficiently harnessing renewable energy and…
View article: Experimental study on the effect of makeup air inlets height on the fire combustion and smoke diffusion
Experimental study on the effect of makeup air inlets height on the fire combustion and smoke diffusion Open
The position of makeup air inlets has significant impacts on fire combustion and the smoke spread characteristics. Therefore, influences of makeup air inlets located at different heights on fire combustion and smoke diffusion were discusse…
View article: The expression spectrum of yak epididymal epithelial cells reveals the functional diversity of caput, corpus and cauda regions
The expression spectrum of yak epididymal epithelial cells reveals the functional diversity of caput, corpus and cauda regions Open
Sperm undergo a series of changes in the epididymis region before acquiring the ability to move and fertilize, and the identification of genes expressed in a region-specific manner in the epididymis provides a valuable insight into functio…
View article: Recombinant FOXN1 fusion protein increases T cell generation in old mice
Recombinant FOXN1 fusion protein increases T cell generation in old mice Open
T cell development in the thymus is dependent on the thymic microenvironment, in which thymic epithelial cells (TECs) are the major component. However, TECs undergo both a qualitative and quantitative loss during aging, which is believed t…
View article: The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration
The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration Open
ER stress inhibits corneal epithelial injury repair and nerve regeneration may be related with the upregulation of SLIT3-ROBO4 pathway.
View article: Plasma leucine-rich α-2 glycoprotein 1 in ST-elevation myocardial infarction: vertical variation, correlation with T helper 17/regulatory T ratio, and predictive value on major adverse cardiovascular events
Plasma leucine-rich α-2 glycoprotein 1 in ST-elevation myocardial infarction: vertical variation, correlation with T helper 17/regulatory T ratio, and predictive value on major adverse cardiovascular events Open
Objective Leucine-rich α-2 glycoprotein 1 (LRG1) promotes inflammation and myocardial injury, but its clinical role in ST-elevation myocardial infarction (STEMI) is rarely disclosed. Herein, this prospective study aimed to explore the valu…
View article: RNA-binding protein RPS7 promotes hepatocellular carcinoma progression via LOXL2-dependent activation of ITGB1/FAK/SRC signaling
RNA-binding protein RPS7 promotes hepatocellular carcinoma progression via LOXL2-dependent activation of ITGB1/FAK/SRC signaling Open
Background Metastasis is one of the leading cause contributes to treatment failure and poor prognosis of hepatocellular carcinoma (HCC) patients. The underlying mechanism of HCC metastasis remains to be determined. Although several RNA bin…
View article: Effects of different feeding methods on serum biochemical indexes, metabolic indexes, immune indexes, and intestinal microorganisms of Nanjiang yellow goats
Effects of different feeding methods on serum biochemical indexes, metabolic indexes, immune indexes, and intestinal microorganisms of Nanjiang yellow goats Open
The intestinal microbiota significantly influences the intake, storage, and absorption of nutrients in animals, thereby greatly impacting the growth and development of the animals. Factors such as diet, animal breed, growth stage, and feed…
View article: The Expression Spectrum of Yak Epididymal Epithelial Cells Reveals the Functional Diversity of Caput, Corpus and Cauda Regions
The Expression Spectrum of Yak Epididymal Epithelial Cells Reveals the Functional Diversity of Caput, Corpus and Cauda Regions Open
View article: A Robust Coverless Image-Synthesized Video Steganography Based on Asymmetric Structure
A Robust Coverless Image-Synthesized Video Steganography Based on Asymmetric Structure Open
View article: <scp>ATAD1</scp> inhibits hepatitis C virus infection by removing the viral <scp>TA</scp>‐protein <scp>NS5B</scp> from mitochondria
<span>ATAD1</span> inhibits hepatitis C virus infection by removing the viral <span>TA</span>‐protein <span>NS5B</span> from mitochondria Open
View article: Administration of recombinant FOXN1 protein attenuates Alzheimer’s pathology in mice
Administration of recombinant FOXN1 protein attenuates Alzheimer’s pathology in mice Open
View article: Amyloid Aggregation and Liquid–Liquid Phase Separation from the Perspective of Phase Transitions
Amyloid Aggregation and Liquid–Liquid Phase Separation from the Perspective of Phase Transitions Open
Amyloid aggregation describes the aberrant self-assembly of peptides into ordered fibrils characterized by cross-β spine cores and is associated with many neurodegenerative diseases and Type 2 diabetes. Oligomers, populated during the earl…
View article: Frontispiz: Highly Active Hydrogen‐rich Photothermal Reverse Water Gas Shift Reaction on Ni/LaInO<sub>3</sub> Perovskite Catalysts with Near‐unity Selectivity
Frontispiz: Highly Active Hydrogen‐rich Photothermal Reverse Water Gas Shift Reaction on Ni/LaInO<sub>3</sub> Perovskite Catalysts with Near‐unity Selectivity Open
Heterogeneous Catalysis. A highly active Ni/LaInO3 perovskite catalyst for the photothermal reverse water gas shift reaction is reported by Langxing Chen, Dongsheng Xu et al. in their Research Article (e202303135).
View article: The mechanism investigation of mutation genes in liver and lung metastasis of colorectal cancer by using NGS technique
The mechanism investigation of mutation genes in liver and lung metastasis of colorectal cancer by using NGS technique Open
Our finding may help clarify the pathogenesis of CRC metastasis more clearly and provide new perspectives for the diagnosis and treatment of CRC metastasis.
View article: BRD4-targeting PROTAC as a unique tool to study biomolecular condensates
BRD4-targeting PROTAC as a unique tool to study biomolecular condensates Open
Biomolecular condensates play key roles in various biological processes. However, specific condensation modulators are currently lacking. PROTAC is a new technology that can use small molecules to degrade target proteins specifically. PROT…
View article: Gold Nanoparticles Reduce Food Sensation in Caenorhabditis elegans via the Voltage-Gated Channel EGL-19 [Corrigendum]
Gold Nanoparticles Reduce Food Sensation in Caenorhabditis elegans via the Voltage-Gated Channel EGL-19 [Corrigendum] Open
[This corrects the article DOI: 10.2147/IJN.S394666.].
View article: Integrated a Fused Silica Capillary Cell and In Situ Raman Spectroscopy for Determining the Solubility of CO2 in n-Decane and n-Decane + n-Hexane System
Integrated a Fused Silica Capillary Cell and In Situ Raman Spectroscopy for Determining the Solubility of CO2 in n-Decane and n-Decane + n-Hexane System Open
Understanding the solubility of CO2 is critical for implementing CO2-enhanced oil recovery (CO2-EOR). In this work, the solubility of CO2 in n-decane in a temperature range between 303.15 K and 353.15 K and pressures up to 15 MPa was measu…
View article: Data from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Data from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway Open
Purpose: To characterize the functional role of SIRT6 in hepatocellular carcinoma (HCC).Experimental Design: The expression of SIRT6 in 60 paired paraffin-embedded HCC tissues and adjacent nontumoral liver tissues was examine…
View article: Supplementary Figure 4 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Supplementary Figure 4 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway Open
SIRT6 regulates cell apoptosis via Bax signaling. mRNA microarray analysis indicated alternations in several key regulators in the Bax-mediated apoptotic pathway. *, p<0.01.
View article: Data from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Data from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway Open
Purpose: To characterize the functional role of SIRT6 in hepatocellular carcinoma (HCC).Experimental Design: The expression of SIRT6 in 60 paired paraffin-embedded HCC tissues and adjacent nontumoral liver tissues was examine…
View article: Supplementary Figure 3 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Supplementary Figure 3 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway Open
SIRT6 overexpression promotes the proliferation of the immortalized liver cell line MIHA. (A) Trypan blue exclusion assay with MIHA cells transduced with lentiviruses expressing plenti6-SIRT6 or the corresponding empty vector. Cell numbers…
View article: Table S1 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Table S1 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway Open
Primers of real-time PCR
View article: Supplementary Figure 3 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway
Supplementary Figure 3 from SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein–Dependent Apoptotic Pathway Open
SIRT6 overexpression promotes the proliferation of the immortalized liver cell line MIHA. (A) Trypan blue exclusion assay with MIHA cells transduced with lentiviruses expressing plenti6-SIRT6 or the corresponding empty vector. Cell numbers…