Zhiqiang Deng
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View article: Ultrasound-based radiomics machine learning models for diagnosing cervical lymph node metastasis in patients with non-small cell lung cancer: a multicentre study
Ultrasound-based radiomics machine learning models for diagnosing cervical lymph node metastasis in patients with non-small cell lung cancer: a multicentre study Open
View article: Molecular engineering of a theranostic molecule that detects Aβ plaques, inhibits Iowa and Dutch mutation Aβ self-aggregation and promotes lysosomal biogenesis for Alzheimer's disease
Molecular engineering of a theranostic molecule that detects Aβ plaques, inhibits Iowa and Dutch mutation Aβ self-aggregation and promotes lysosomal biogenesis for Alzheimer's disease Open
Aβ specific theranostic small molecule, F-SLCOOH inhibits Aβ self-aggregation and promotes lysosomal biogenesis in Alzheimer’s disease models.
View article: Discussion on the Application of Integrated Aerogeophysical Method in Urban Site Selection and Construction
Discussion on the Application of Integrated Aerogeophysical Method in Urban Site Selection and Construction Open
As the construction of "Belt and Road Initiative" continues to advance, cities and large-scale infrastructure construction will be ushered in along the route, and there is an urgent need to quickly identify the geological situation of the …
View article: An Indirect Prediction Method based on Feature Extraction of Lithium-ion Batteries Remaining Useful Life
An Indirect Prediction Method based on Feature Extraction of Lithium-ion Batteries Remaining Useful Life Open
Predicting the remaining useful life (RUL) of lithium-ion batteries is of paramount significance for the lifespan management of electric vehicles. This study delves into a feature extraction-based approach for indirectly predicting RUL in …
View article: Effectiveness of Virtual Reality on the Caregiving Competence and Empathy of Caregivers for Elderly with Chronic Diseases: A Systematic Review and Meta-Analysis
Effectiveness of Virtual Reality on the Caregiving Competence and Empathy of Caregivers for Elderly with Chronic Diseases: A Systematic Review and Meta-Analysis Open
Aims. To synthesize evidence on the effectiveness of virtual reality-based training of caregivers for the elderly with chronic diseases. Background. With a growing number of elderly suffering from chronic diseases, caregivers who lack the …
View article: An Object SLAM Framework for Association, Mapping, and High-Level Tasks
An Object SLAM Framework for Association, Mapping, and High-Level Tasks Open
Object SLAM is considered increasingly significant for robot high-level perception and decision-making. Existing studies fall short in terms of data association, object representation, and semantic mapping and frequently rely on additional…
View article: The application of radiomics in esophageal cancer: Predicting the response after neoadjuvant therapy
The application of radiomics in esophageal cancer: Predicting the response after neoadjuvant therapy Open
Esophageal cancer (EC) is one of the fatal malignant neoplasms worldwide. Neoadjuvant therapy (NAT) combined with surgery has become the standard treatment for locally advanced EC. However, the treatment efficacy for patients with EC who r…
View article: Editorial: Autophagy in diseases—From basic to clinic
Editorial: Autophagy in diseases—From basic to clinic Open
EDITORIAL article Front. Physiol., 04 January 2023Sec. Cell Physiology Volume 13 - 2022 | https://doi.org/10.3389/fphys.2022.1115511
View article: Open Arthrolysis for Chronic Elbow Dislocation with Extremely Severe Stiffness in Children
Open Arthrolysis for Chronic Elbow Dislocation with Extremely Severe Stiffness in Children Open
Objective Studies on extremely severe elbow stiffness after chronic dislocation in children are scarce. This study aims to investigate the choice of surgical treatment modalities and to analyze their treatment efficacy in children with chr…
View article: Editorial: Assessing the Pharmacological Effects and Therapeutic Potential of Traditional Chinese Medicine in Neurological Disease Models: An Update
Editorial: Assessing the Pharmacological Effects and Therapeutic Potential of Traditional Chinese Medicine in Neurological Disease Models: An Update Open
EDITORIAL article Front. Pharmacol., 27 April 2022Sec. Ethnopharmacology Volume 13 - 2022 | https://doi.org/10.3389/fphar.2022.909153
View article: Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles Open
View article: Autophagy deficiency in neurodevelopmental disorders
Autophagy deficiency in neurodevelopmental disorders Open
Autophagy is a cell self-digestion pathway through lysosome and plays a critical role in maintaining cellular homeostasis and cytoprotection. Characterization of autophagy related genes in cell and animal models reveals diverse physiologic…
View article: Risk factors for 30-day readmission in patients with ischemic stroke: a systematic review and meta-analysis
Risk factors for 30-day readmission in patients with ischemic stroke: a systematic review and meta-analysis Open
The 30-day readmission rates of ischemic stroke survivors ranged from 1.41% to 27.64% and remained challenging. We found that stroke history, diabetes mellitus, hypertension, atrial fibrillation, heart failure, and advanced age were risk f…
View article: Selective autophagy of AKAP11 activates cAMP/PKA to fuel mitochondrial metabolism and tumor cell growth
Selective autophagy of AKAP11 activates cAMP/PKA to fuel mitochondrial metabolism and tumor cell growth Open
Significance Autophagy is known to promote cell survival through providing various sources of fuels as a result of digestion. Here, we uncover a function of autophagy in cell metabolic regulation by directly activating cAMP/PKA signaling t…
View article: Hybrid modeling and prediction of oyster norovirus outbreaks
Hybrid modeling and prediction of oyster norovirus outbreaks Open
This paper presents a hybrid model for predicting oyster norovirus outbreaks by combining the Artificial Neural Networks (ANNs) and Principal Component Analysis (PCA) methods and using the Moderate Resolution Imaging Spectroradiometer (MOD…
View article: Object-Driven Active Mapping for More Accurate Object Pose Estimation and Robotic Grasping.
Object-Driven Active Mapping for More Accurate Object Pose Estimation and Robotic Grasping. Open
This paper presents the first active object mapping framework for complex robotic grasping tasks. The framework is built on an object SLAM system integrated with a simultaneous multi-object pose estimation process. Aiming to reduce the obs…
View article: Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia Open
On the basis of this information, there is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019. Considerable efforts to reduce transmission will be required to control outbreaks if …
View article: CCDC 1964092: Experimental Crystal Structure Determination
CCDC 1964092: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: First Outbreak of Occupational Brucellosis Involving Multiple Clusters — Hubei Province, China, 2019
First Outbreak of Occupational Brucellosis Involving Multiple Clusters — Hubei Province, China, 2019 Open
In addition to measures aimed at this outbreak, the local agricultural department has issued special notices based on this investigation to adjust and strengthen local eradication program of brucellosis.
View article: ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway Open
Macroautophagy (autophagy) is a key catabolic pathway for the maintenance of proteostasis through constant digestion of selective cargoes. The selectivity of autophagy is mediated by autophagy receptors that recognize and recruit cargoes t…
View article: ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway Open
Macroautophagy (autophagy) is a key catabolic pathway for the maintenance of proteostasis through constant digestion of selective cargoes. The selectivity of autophagy is mediated by autophagy receptors that recognize and recruit cargoes t…
View article: An Outbreak of Multidrug-Resistant Tuberculosis in a Secondary School — Hubei Province, 2019
An Outbreak of Multidrug-Resistant Tuberculosis in a Secondary School — Hubei Province, 2019 Open
The implementation of TB prevention and control measures in schools is important to increase knowledge on TB and to raise awareness on protecting personal wellbeing. The Automatic Early Warning Information System alerted the local health d…
View article: ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway Open
Macroautophagy (autophagy) is a key catabolic pathway for the maintenance of proteostasis through constant digestion of selective cargoes. The selectivity of autophagy is mediated by autophagy receptors that recognize and recruit cargoes t…
View article: Uncertainty Analysis of Watershed-Based Flow and Water Quality Modelling with Different DEM Data Sources
Uncertainty Analysis of Watershed-Based Flow and Water Quality Modelling with Different DEM Data Sources Open
DEMs are important data required in watershed-based hydrological and water quality modeling since they are employed to derive critical characteristics of watershed through a watershed delineation process. This study aims to analyze the unc…
View article: Predicting Bacterial Levels in Recreational Beach Waters along U.S. Gulf Coast
Predicting Bacterial Levels in Recreational Beach Waters along U.S. Gulf Coast Open
A Bayesian model was proposed for daily predictions of the probability of water quality standard violation of enterococci (ENT) levels in recreational beach waters. The Bayesian model consisted of a prior distribution and a likelihood func…
View article: Numerical and experimental research on vibration mechanism of rotary compressor.
Numerical and experimental research on vibration mechanism of rotary compressor. Open
With a typical rotary compressor as the research object, the vibration mechanism of the rotary compressor was analyzed in detail in this work. And according to the work, the formulations of the tangential vibration and the radial vibration…
View article: Research on low frequency noise caused by beat vibration of rotary compressor.
Research on low frequency noise caused by beat vibration of rotary compressor. Open
The discontinuity of low frequency noise caused by beat frequency vibration of rotary compressor is studied in this paper. Based on beat frequency theoretical analysis, a finite element model is established to simulate the electromagnetic …
View article: Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?
Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease? Open
View article: Mechanistic investigation on radical-induced construction of oxindoles: radical versus electrophilic cyclization
Mechanistic investigation on radical-induced construction of oxindoles: radical versus electrophilic cyclization Open
A four-step mechanism is established for the title reaction and the radical cyclization is updated to the cationic cyclization.
View article: ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models
ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models Open