Zhichun Lu
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View article: Molecular and Clinicopathological Profiling of Clear Cell Renal Cell Carcinoma with Rhabdoid Features: An Integrative Pathway-Based Stratification Approach
Molecular and Clinicopathological Profiling of Clear Cell Renal Cell Carcinoma with Rhabdoid Features: An Integrative Pathway-Based Stratification Approach Open
Background: Clear cell renal cell carcinoma with rhabdoid features (ccRCC-R) is a highly aggressive variant of renal cell carcinoma that carries a poor prognosis and limited treatment options. Methods: To better define the clinicopathologi…
View article: Multifocal Superficial Squamous Cell Carcinoma Arising in the Setting of Esophageal Intramural Pseudodiverticulosis
Multifocal Superficial Squamous Cell Carcinoma Arising in the Setting of Esophageal Intramural Pseudodiverticulosis Open
Esophageal intramural pseudodiverticulosis (EIPD) is a rare disease characterized endoscopically by numerous small outpouchings within the esophageal wall. While typically associated with benign symptoms such as dysphagia, EIPD has been li…
View article: Hereditary papillary renal cell carcinoma
Hereditary papillary renal cell carcinoma Open
Hereditary papillary renal cell carcinoma (HPRCC) is an autosomal dominant syndrome characterized by the occurrence of bilateral and multifocal, classic type papillary renal cell carcinomas. In the recent decades, extensive molecular studi…
View article: Experimental study on strength and failure characteristics of sandstone rock mass with complex cataclastic structure using 3D printing models
Experimental study on strength and failure characteristics of sandstone rock mass with complex cataclastic structure using 3D printing models Open
A cataclastic rock mass is a poor type of engineering geological rock mass. The determination of the shear failure characteristics and shear strengths of cataclastic rock masses can provide key basis for the design and construction of infr…
View article: The Role of α-Smooth Muscle Actin in Confirming the Microinvasion of Laryngeal Squamous Cell Carcinoma
The Role of α-Smooth Muscle Actin in Confirming the Microinvasion of Laryngeal Squamous Cell Carcinoma Open
BackgroundThe diagnosis of microinvasive laryngeal squamous cell carcinoma (mLSCC) is not always straightforward and sometimes can be very challenge in daily clinical practice, particularly in the circumstances with differentials such as S…
View article: Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1,<i>ETV1</i>, and<i>ETV4</i>on whole mount radical prostatectomy tissue
Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1,<i>ETV1</i>, and<i>ETV4</i>on whole mount radical prostatectomy tissue Open
Expression profiles of ETS related genes and SPINK1 in early onset prostate cancer have not been thoroughly explored. We retrieved 151 radical prostatectomy specimens from young men with prostate cancer (<55yrs) and characterized the expre…
View article: Mucinous Adenocarcinoma Arising from Perianal Fistulae in Crohn’s Disease: A Rare Case Report and Review of the Literature
Mucinous Adenocarcinoma Arising from Perianal Fistulae in Crohn’s Disease: A Rare Case Report and Review of the Literature Open
Perianal fistula is a common manifestation of Crohn's disease. Adenocarcinoma arising from perianal fistulae in patients with Crohn’s disease is rare. There are only 65 cases in English literature with anorectal adenocarcinoma arising from…