Zhiduo Hou
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View article: TGF-β1 promotes collagen synthesis in systemic sclerosis via upregulating P4HA3
TGF-β1 promotes collagen synthesis in systemic sclerosis via upregulating P4HA3 Open
Our results suggest that P4HA3 is upregulated by TGF-β1 secreted from immune cells to promote collagen synthesis in SSc. Inhibition of C-P4Hs is a potential therapeutic approach for SSc fibrosis.
View article: Risk Factors for Delayed Facial Palsy Following Microvascular Decompression in Hemifacial Spasm: A Systematic Review and Meta-Analysis
Risk Factors for Delayed Facial Palsy Following Microvascular Decompression in Hemifacial Spasm: A Systematic Review and Meta-Analysis Open
DFP is a relatively common complication after MVD, and facial nerve indentation, prolonged disease duration, and the presence of multiple offending vessels significantly increase DFP risk.
View article: Profiling of IgG N-glycosylation for axial spondyloarthritis and other rheumatic diseases
Profiling of IgG N-glycosylation for axial spondyloarthritis and other rheumatic diseases Open
View article: Ubiquitination and Deubiquitination in Osteoarthritis: From Mechanisms to Therapeutic Advances
Ubiquitination and Deubiquitination in Osteoarthritis: From Mechanisms to Therapeutic Advances Open
Chronic osteoarthritis (OA) is distinguished by the deterioration of cartilage within joints, resulting in pain and reduced joint function.With the aging of the population, the prevalence of OA is increasing, becoming a public health issue…
View article: Altered dynamic functional network connectivity in rheumatoid arthritis associated with peripheral inflammation and neuropsychiatric disorders
Altered dynamic functional network connectivity in rheumatoid arthritis associated with peripheral inflammation and neuropsychiatric disorders Open
Objective This study explored the dynamic functional connective (DFC) alterations in patients with rheumatoid arthritis (RA) and investigated the correlation between the neuropsychiatric symptoms, peripheral inflammation and DFC alteration…
View article: Functional dysconnectivity and microstructural impairment of the cortico-thalamo-cortical network in women with rheumatoid arthritis: A multimodal MRI study
Functional dysconnectivity and microstructural impairment of the cortico-thalamo-cortical network in women with rheumatoid arthritis: A multimodal MRI study Open
View article: Table of Contents
Table of Contents Open
View article: Comparison of clinical characteristics between adult-onset and juvenile-onset non-radiographic axial spondyloarthritis in Chinese patients: results from the COCAS cohort
Comparison of clinical characteristics between adult-onset and juvenile-onset non-radiographic axial spondyloarthritis in Chinese patients: results from the COCAS cohort Open
View article: Endothelial mesenchymal transition promotes pannus formation in ankylosing spondylitis by activation of TGF-β/SMAD signalling pathway
Endothelial mesenchymal transition promotes pannus formation in ankylosing spondylitis by activation of TGF-β/SMAD signalling pathway Open
Our findings show that EndMT is involved in the promotion of pannus formation by TGF-β/SMAD signalling pathway activation in AS.
View article: Enhanced activity of the left precuneus as a predictor of visuospatial dysfunction correlates with disease activity in rheumatoid arthritis
Enhanced activity of the left precuneus as a predictor of visuospatial dysfunction correlates with disease activity in rheumatoid arthritis Open
View article: Tumor Necrosis Factor-Alpha (+489 G/A) Polymorphism Can Predict the Response to Adalimumab in Chinese Han Patients With Ankylosing Spondylitis
Tumor Necrosis Factor-Alpha (+489 G/A) Polymorphism Can Predict the Response to Adalimumab in Chinese Han Patients With Ankylosing Spondylitis Open
The patients carrying the TNFα +489 A allele may be more likely to experience better therapeutic efficacy and achieve the treatment target (ASAS-PR, ASAS40 response, or ASDAS-MI) after receiving ADA treatment. Detection of TNFα
View article: Systemic lupus erythematosus with acquired hemophilia A: A case report and literature review.
Systemic lupus erythematosus with acquired hemophilia A: A case report and literature review. Open
Systemic lupus erythematosus (SLE) complicated with acquired hemophilia A (AHA) is a rare condition with frequently delayed diagnosis and a high mortality rate, so it is necessary to strengthen the understanding of this disease. In this st…
View article: Risk factors for progression of juvenile-onset non-radiographic axial spondyloarthritis to juvenile-onset ankylosing spondylitis: a nested case–control study
Risk factors for progression of juvenile-onset non-radiographic axial spondyloarthritis to juvenile-onset ankylosing spondylitis: a nested case–control study Open
Objective To evaluate the clinical characteristics of juvenile-onset non-radiographic axial spondyloarthritis (nr-axSpA) and to investigate risk factors associated with progression to juvenile-onset ankylosing spondylitis (JoAS). Methods A…
View article: Long-term outcomes of patients with systemic lupus erythematosus: A Multicenter Cohort Study from CSTAR registry
Long-term outcomes of patients with systemic lupus erythematosus: A Multicenter Cohort Study from CSTAR registry Open
Objective To study the long-term outcomes, in the context of both mortality and organ damage in patients with systemic lupus erythematosus (SLE) in the Chinese SLE Treatment and Research group (CSTAR) registry cohort. Methods Patients were…
View article: Comparison of Sacroiliac Biopsies and Magnetic Resonance Imaging Examinations in Non-Radiographic Axial Spondyloarthritis
Comparison of Sacroiliac Biopsies and Magnetic Resonance Imaging Examinations in Non-Radiographic Axial Spondyloarthritis Open
Background : Early diagnosis and treatment are the key to improve the prognosis of axial spondyloarthritis (axSpA), therefore, we aimed to evaluate the diagnostic value of magnetic resonance imaging (MRI) and pathological examination of th…
View article: Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis
Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis Open
View article: Impaired decision‐making and functional neuronal network activity in systemic lupus erythematosus
Impaired decision‐making and functional neuronal network activity in systemic lupus erythematosus Open
Background Systemic lupus erythematosus (SLE) is associated with cognitive deficit but the exact neural mechanisms remain unclear. Purpose To explore sequential brain activities using functional magnetic resonance imaging (fMRI) during the…
View article: Bone edema on magnetic resonance imaging is highly associated with low bone mineral density in patients with ankylosing spondylitis
Bone edema on magnetic resonance imaging is highly associated with low bone mineral density in patients with ankylosing spondylitis Open
Low BMD is common in AS patients. BME on MRI is highly associated with low BMD at both the spine and femur.
View article: Changes in the Prevalence of Rheumatic Diseases in Shantou, China, in the Past Three Decades: A COPCORD Study
Changes in the Prevalence of Rheumatic Diseases in Shantou, China, in the Past Three Decades: A COPCORD Study Open
This study aimed to clarify changes in the prevalence of rheumatic diseases in Shantou, China, in the past 3 decades and validate whether stair-climbing is a risk factor for knee pain and knee osteoarthritis (KOA). The World Health Organiz…
View article: A long-term, observational cohort study on the safety of low-dose glucocorticoids in ankylosing spondylitis: adverse events and effects on bone mineral density, blood lipid and glucose levels and body mass index
A long-term, observational cohort study on the safety of low-dose glucocorticoids in ankylosing spondylitis: adverse events and effects on bone mineral density, blood lipid and glucose levels and body mass index Open
Objectives This study aimed to investigate the risk of adverse events and effects on bone mineral density (BMD), blood lipid and glucose levels and body mass index (BMI) of low-dose glucocorticoid (GC) treatment in ankylosing spondylitis. …