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MiR‐21‐5p/dual‐specificity phosphatase 8 signalling mediates the anti‐inflammatory effect of haem oxygenase‐1 in aged intracerebral haemorrhage rats Open

Yetong Ouyang, Dongling Li, Han Wang, Zhigang Wan, Qinghua Luo , et al. · 2019

Biology

Intracerebral haemorrhage (ICH) is a severe neurological disorder caused by bleeding within the brain tissue. Inflammation has been implicated in ICH pathogenesis and is a potential therapeutic target for ICH. Haemin, an activator of haem …

Effects of different doses of dexmedetomidine on analgesic efficacy and inflammatory cytokines in patients undergoing laparoscopic surgery Open

Zhigang Wan, Jie Wang, Hui Cao, Lili Wu · 2018

Medicine

The effects of different doses of dexmedetomidine on analgesic efficacy and inflammatory cytokines in patients with laparoscopic surgery were investigated. A total of 179 laparoscopic patients from March 2015 to May 2017 were enrolled and …

The evaluation of bio-mechanical properties of four different skull implants by finite element methods Open

Zhigang Wan, Chi-Wen Huang, Yunqing Li, Caihong Wan, Rongde Zhong · 2018

Materials science Engineering Mathematics

Cranioplasty helps to restore skull's integrity, stability the state of the intracranial structure, also to improve the aesthetic immensely and reduce the concerns caused by weakened of brain protection with decompressive craniectomy. By u…

Clinical factors and safety of microvascular decompression in the treatment of trigeminal neuralgia Open

Chi-Wen Huang, Zhigang Wan, Caihong Wan, Yun-Qing Li, Rongde Zhong · 2018

Medicine Chemistry

Objectives: This study was aimed to investigate the clinical factors and safety of Microvascular Decompression (MVD) in the treatment of Trigeminal Neuralgia (TN). Methods: The clinical characteristics, intraoperative findings, effectivity…

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