Zhihui Qu
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View article: Whole-body water mass and kidney function: a Mendelian randomization study
Whole-body water mass and kidney function: a Mendelian randomization study Open
Background The morbidity and mortality of chronic kidney disease (CKD) are increasing worldwide, making it a serious public health problem. Although a potential correlation between body water content and CKD progression has been suggested,…
View article: Prediction of immunotherapy response in idiopathic membranous nephropathy using deep learning-pathological and clinical factors
Prediction of immunotherapy response in idiopathic membranous nephropathy using deep learning-pathological and clinical factors Open
Background Owing to individual heterogeneity, patients with idiopathic membranous nephropathy (IMN) exhibit varying sensitivities to immunotherapy. This study aimed to establish and validate a model incorporating pathological and clinical …
View article: Shenkang protects renal function in diabetic rats by preserving nephrin expression
Shenkang protects renal function in diabetic rats by preserving nephrin expression Open
Background Shenkang injection has been used clinically to lower creatinine levels. This study explored the mechanism of Shenkang injection on protecting kidney function from hyperglycemia-mediated damage. Methods This study utilized a STre…
View article: Study on the remediation of hexavalent chromium groundwater by zero-valent iron
Study on the remediation of hexavalent chromium groundwater by zero-valent iron Open
This study investigates the potential problems of zero-valent iron remediation of hexavalent chromium contamination by varying the type and dosage of zero-valent iron, finding a suitable zero-valent iron reaction material for application i…
View article: Elevated number of IL-21+ TFH and CD86+CD38+ B cells in blood of renal transplant recipients with AMR under conventional immuno-suppression
Elevated number of IL-21+ TFH and CD86+CD38+ B cells in blood of renal transplant recipients with AMR under conventional immuno-suppression Open
The objective of this study is to detect the number of different subsets of TFH and B cells in renal transplant recipients (RTR) with antibody-mediated acute rejection (AMR), acute rejection (AR), chronic rejection (CR), or transplant stab…
View article: Increased frequency of PD-1hiCXCR5- T cells and B cells in patients with newly diagnosed IgA nephropathy
Increased frequency of PD-1hiCXCR5- T cells and B cells in patients with newly diagnosed IgA nephropathy Open
View article: Increased soluble ST2 and IL‑4 serum levels are associated with disease severity in patients with membranous nephropathy
Increased soluble ST2 and IL‑4 serum levels are associated with disease severity in patients with membranous nephropathy Open
The interleukin (IL)‑33/suppression of tumorigenicity 2 (ST2) axis regulates Th2 reactivity, and ST2 is the receptor for IL‑33. In this study, the roles of IL‑33 and soluble ST2 (sST2) in the pathogenesis of membranous nephropathy (MN), an…
View article: Orientin Ameliorates LPS‐Induced Inflammatory Responses through the Inhibitory of the NF‐<i>κ</i>B Pathway and NLRP3 Inflammasome
Orientin Ameliorates LPS‐Induced Inflammatory Responses through the Inhibitory of the NF‐<i>κ</i>B Pathway and NLRP3 Inflammasome Open
Inflammation is a complex response to diverse pathological conditions, resulting in negative rather than protective effects when uncontrolled. Orientin (Ori), a flavonoid component isolated from natural plants, possesses abundant propertie…
View article: A Lower Proportion of Regulatory B Cells in Patients with Henoch–Schoenlein Purpura Nephritis
A Lower Proportion of Regulatory B Cells in Patients with Henoch–Schoenlein Purpura Nephritis Open
Our results suggest that CD38+CD19+ and CD1d+CD5+CD19+ B cells (Bregs) contribute to the pathogenesis of HSPN.
View article: A higher frequency of <scp>IL</scp>‐10‐producing B cells in Hepatitis B virus‐associated membranous nephropathy
A higher frequency of <span>IL</span>‐10‐producing B cells in Hepatitis B virus‐associated membranous nephropathy Open
Summary The purpose of this study is to elucidate the potential role of interleukin ( IL )‐10 + regulatory B cells and other B cell subsets in the development of hepatitis B virus‐associated membranous nephropathy ( HBV ‐ MN ). A total of …