Zhilei Mao
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View article: One-pot one-step detection platform for severe fever with thrombocytopenia syndrome virus via the CRISPR/Cas12a detection system
One-pot one-step detection platform for severe fever with thrombocytopenia syndrome virus via the CRISPR/Cas12a detection system Open
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus that primarily causes SFTS. Although a common testing route is available, a timely, conventional and accurate method for SFTSV detection is urgently needed. In…
View article: Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma
Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma Open
Radiotherapy (RT) is the primary treatment modality for nasopharyngeal carcinoma (NPC). However, the tumor microenvironment (TME)-induced radioresistance often compromises its therapeutic efficacy. Herein, we propose an innovative bidirect…
View article: TLR4 as a Potential Target of Me-PFOSA-AcOH Leading to Cardiovascular Diseases: Evidence from NHANES 2013–2018 and Molecular Docking
TLR4 as a Potential Target of Me-PFOSA-AcOH Leading to Cardiovascular Diseases: Evidence from NHANES 2013–2018 and Molecular Docking Open
Background: Concerns have been raised regarding the effects of perfluoroalkyl substance (PFAS) exposure on cardiovascular diseases (CVD), but clear evidence linking PFAS exposure to CVD is lacking, and the mechanism remains unclear. Object…
View article: Titanium Dioxide Nanoparticles Induce Maternal Preeclampsia-like Syndrome and Adverse Birth Outcomes via Disrupting Placental Function in SD Rats
Titanium Dioxide Nanoparticles Induce Maternal Preeclampsia-like Syndrome and Adverse Birth Outcomes via Disrupting Placental Function in SD Rats Open
The escalating utilization of titanium dioxide nanoparticles (TiO2 NPs) in everyday products has sparked concerns regarding their potential hazards to pregnant females and their offspring. To address these concerns and shed light on their …
View article: Prevalence and Related Factors of Rupture among Cases with Ectopic Pregnancy; a Systematic Review and Meta-Analysis.
Prevalence and Related Factors of Rupture among Cases with Ectopic Pregnancy; a Systematic Review and Meta-Analysis. Open
Based on the findings, 56.4% of EP cases experienced rupture and various factors influence its prevalence. As a result, health managers and policymakers can address and mitigate modifiable factors contributing to rupture in EP cases by imp…
View article: Serum Concentrations of Benzaldehyde, Isopentanaldehyde and Sex Hormones: Evidence from the National Health and Nutrition Examination Survey
Serum Concentrations of Benzaldehyde, Isopentanaldehyde and Sex Hormones: Evidence from the National Health and Nutrition Examination Survey Open
Exposure to environmental chemicals could disturb the balance of sex hormones. However, the studies on Benzaldehyde, Isopentanaldehyde exposure and sex hormones are still limited. Based on the data of 1064 participants in the National Heal…
View article: Glutamine coated titanium for synergistic sonodynamic and photothermal on tumor therapy upon targeted delivery
Glutamine coated titanium for synergistic sonodynamic and photothermal on tumor therapy upon targeted delivery Open
Introduction: The application of titanium dioxide nanoparticles (TiO 2 NPs) for cancer therapy has been studied for decades; however, the targeted delivery of TiO 2 NPs to tumor tissues is challenging, and its efficiency needs to be improv…
View article: Corrigendum: Phytochromes A and B mediate light stabilization of BIN2 to regulate brassinosteroid signaling and photomorphogenesis in Arabidopsis
Corrigendum: Phytochromes A and B mediate light stabilization of BIN2 to regulate brassinosteroid signaling and photomorphogenesis in Arabidopsis Open
[This corrects the article DOI: 10.3389/fpls.2022.865019.].
View article: Construction and validation of a novel prognostic model using the cellular senescence-associated long non-coding RNA in gastric cancer: a biological analysis
Construction and validation of a novel prognostic model using the cellular senescence-associated long non-coding RNA in gastric cancer: a biological analysis Open
Taken together, these results suggest that cellular senescence-related lncRNAs are likely to be valuable prognostic markers for GC. They also reflect the situation of the STAD immune microenvironment and may provide direction for future GC…
View article: miR-99 family is potential target to reverse cerium dioxide nanoparticle-induced placental cell dysfunction
miR-99 family is potential target to reverse cerium dioxide nanoparticle-induced placental cell dysfunction Open
CeO2 NPs impaired the invasive and migratory abilities, which play an important role in embryo implantation, as well as determining placental function and embryonic development.
View article: HPV-16 E7-Specific Cellular Immune Response in Women With Cervical Intraepithelial Lesion Contributes to Viral Clearance: A Cross-Sectional and Longitudinal Clinical Study
HPV-16 E7-Specific Cellular Immune Response in Women With Cervical Intraepithelial Lesion Contributes to Viral Clearance: A Cross-Sectional and Longitudinal Clinical Study Open
High-risk human papillomavirus (HPV) infection is the cause of almost all cervical cancers. HPV16 is one of the main risk subtypes. Although screening programs have greatly reduced the prevalence of cervical cancer in developed countries, …
View article: Vitamin D deficiency inhibits microRNA-196b-5p which regulates ovarian granulosa cell hormone synthesis, proliferation, and apoptosis by targeting RDX and LRRC17
Vitamin D deficiency inhibits microRNA-196b-5p which regulates ovarian granulosa cell hormone synthesis, proliferation, and apoptosis by targeting RDX and LRRC17 Open
This study shows that miR-196b-5p can regulate the oxidative stress (OS), glucose uptake, and steroid production pathway of GCs, thus promoting follicular development and maturation. This is a step towards a feasible treatment for PCOS.
View article: Application of ultra pulse CO2 lattice laser in the treatment of female urinary incontinence
Application of ultra pulse CO2 lattice laser in the treatment of female urinary incontinence Open
The CO2 lattice laser is safe and effective in the treatment of mild and moderate urinary incontinences in female patients, which can effectively improve the symptom of urinary leakage without obvious adverse reactions.
View article: Risk factors for respiratory assistance in premature infants
Risk factors for respiratory assistance in premature infants Open
Premature infants are prone to dyspnea after birth due to immature development, and some infants require respiratory assistance. However, the risk factors for respiratory assistance in premature infants are rarely reported. The present stu…
View article: Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China
Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China Open
RRT is an acceptable method for sensitive question surveys within sensitive populations, and this new sampling method is liable to be used for sensitive question surveys of large populations. We believe that the results obtained in the fie…
View article: A randomized clinical study of the treatment of white lesions of the vulva with a fractional ultrapulsed CO2 laser
A randomized clinical study of the treatment of white lesions of the vulva with a fractional ultrapulsed CO2 laser Open
Fractional ultrapulsed CO2 laser is a minimally invasive, effective, and safe treatment for white lesions of the vulva. It causes few complications and does not affect the daily and working life of patients. Therefore, it should be widely …
View article: A review of the research progress in T-lymphocyte immunity and cervical cancer
A review of the research progress in T-lymphocyte immunity and cervical cancer Open
Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T-cell immunity requires the participation of many factors, such as antigen-presenting cells (APCs), cytokines, co-stimulatory molecules, etc. HPV…
View article: The mTOR/GCLc/GSH Pathway Mediates the Dose-Dependent Bidirectional Regulation of ROS Induced by TiO<sub>2</sub>NPs in Neurogenic Cells
The mTOR/GCLc/GSH Pathway Mediates the Dose-Dependent Bidirectional Regulation of ROS Induced by TiO<sub>2</sub>NPs in Neurogenic Cells Open
Objective . The effect of TiO 2 NP exposure on the nervous system and the underlying mechanism remain unclear. The antioxidant effect of TiO 2 NPs at a low dose was newly found in our study, which was different from the effect at high dose…
View article: Correction: Perfluorooctane Sulfonate Disturbs Nanog Expression through miR-490-3p in Mouse Embryonic Stem Cells
Correction: Perfluorooctane Sulfonate Disturbs Nanog Expression through miR-490-3p in Mouse Embryonic Stem Cells Open
[This corrects the article DOI: 10.1371/journal.pone.0074968.].
View article: Correction: Metabolomic profiles delineate the potential role of glycine in gold nanorod-induced disruption of mitochondria and blood–testis barrier factors in TM-4 cells
Correction: Metabolomic profiles delineate the potential role of glycine in gold nanorod-induced disruption of mitochondria and blood–testis barrier factors in TM-4 cells Open
Correction for ‘Metabolomic profiles delineate the potential role of glycine in gold nanorod-induced disruption of mitochondria and blood–testis barrier factors in TM-4 cells’ by Bo Xu et al., Nanoscale, 2014, 6, 8265–8273.
View article: Correction: Corrigendum: Metabolomics reveals metabolic changes in male reproductive cells exposed to thirdhand smoke
Correction: Corrigendum: Metabolomics reveals metabolic changes in male reproductive cells exposed to thirdhand smoke Open
Scientific Reports 5: Article number: 15512; published online: 22 October 2015; updated: 13 April 2016 The Acknowledgements section in this Article is incomplete. “This study was supported by National 973 Program (2012CBA01305); National S…