Zhiwei Cai
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View article: Prospective associations between the trajectory of the Chinese visceral adiposity index and risk of new-onset heart failure
Prospective associations between the trajectory of the Chinese visceral adiposity index and risk of new-onset heart failure Open
Long-term high CVAI is associated with higher risk of HF, irrespective of conventional risk factors. The regular monitoring of CVAI may help identify individuals at high risk of HF in the general population.
View article: Hybrid Control Switching Technology for LLC Resonant Converter
Hybrid Control Switching Technology for LLC Resonant Converter Open
Aiming at the problem of the circuit operating frequency changing beyond the regulation range and zero switching not being guaranteed when the input voltage range of the LLC resonant converter is large, a hybrid control technology with a v…
View article: Machine-learning-based prediction by stacking ensemble strategy for surgical outcomes in patients with degenerative cervical myelopathy
Machine-learning-based prediction by stacking ensemble strategy for surgical outcomes in patients with degenerative cervical myelopathy Open
The ensemble classifiers successfully predict the JOA recovery rate in DCM patients, which showed a high potential for assisting physicians in managing DCM patients and making full use of medical resources.
View article: Association between the atherogenic index of plasma trajectory and risk of heart failure among hypertensive patients: a prospective cohort study
Association between the atherogenic index of plasma trajectory and risk of heart failure among hypertensive patients: a prospective cohort study Open
Prolonged elevation of AIP in hypertensive patients is significantly associated with an increased risk of HF. This finding suggests that regular monitoring of AIP could aid in identifying individuals at a heightened risk of HF within the h…
View article: Increased Risk of Cardiometabolic Disease in Ideal Weight Adults With History of Overweight/Obesity in China: A Prospective Cohort Study
Increased Risk of Cardiometabolic Disease in Ideal Weight Adults With History of Overweight/Obesity in China: A Prospective Cohort Study Open
Background Overweight and obesity represent critical modifiable determinants in the prevention of cardiometabolic disease (CMD). However, the long‐term impact of prior overweight/obesity on the risk of CMD in later life remains unclear. We…
View article: Pathogen spectrum changes of respiratory tract infections in children in Chaoshan area under the influence of COVID-19
Pathogen spectrum changes of respiratory tract infections in children in Chaoshan area under the influence of COVID-19 Open
Background: From January 24, 2020 to May 18, 2020, Chaoshan took measures to limit the spread of COVID-19, such as restricting public gatherings, wearing masks, and suspending classes. This study explored the effects of these measures on t…
View article: Contents: steel research int. 12/2023
Contents: steel research int. 12/2023 Open
In article 2300137, Lei Zhang and co-workers investigate
View article: Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study Open
Background Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke. Therefore, we aimed to characteriz…
View article: Accumulated exposure to high non-high-density lipoprotein cholesterol increases the risk of cardiovascular diseases in hypertensive individuals: An 11-year prospective cohort study
Accumulated exposure to high non-high-density lipoprotein cholesterol increases the risk of cardiovascular diseases in hypertensive individuals: An 11-year prospective cohort study Open
A consistently high non-HDL-C concentration increases the risk of CVD in individuals with hypertension, as does prolonged exposure to a high non-HDL-C concentration. Thus, the achievement of target blood pressure and non-HDL-C concentratio…
View article: Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study
Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study Open
Background The relationship of cumulative remnant-cholesterol (Cum-RC) concentration with the risk of cardiovascular disease (CVD) in patients with hypertension remains unclear. Methods We studied data for 28,698 individuals for whom three…
View article: Epidemiological and clinical features, treatment status, and economic burden of traumatic spinal cord injury in China: a hospital-based retrospective study
Epidemiological and clinical features, treatment status, and economic burden of traumatic spinal cord injury in China: a hospital-based retrospective study Open
JOURNAL/nrgr/04.03/01300535-202405000-00044/inline-graphic1/v/2023-09-28T063346Z/r/image-tiff Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death. China has the largest population of …
View article: Age-dependent changes in the risk of weight gain in Chinese adults: results from the Kailuan cohort study
Age-dependent changes in the risk of weight gain in Chinese adults: results from the Kailuan cohort study Open
The risk of weight gain in Chinese adults is age dependent, and clear public healthcare messaging is needed for young adults who are at the highest risk of weight gain.
View article: The effect of acute aerobic exercise on arterial stiffness in individuals with different body fat percentages: A cross-sectional study
The effect of acute aerobic exercise on arterial stiffness in individuals with different body fat percentages: A cross-sectional study Open
Background Body fat percentage were positively correlated with arterial stiffness, but the acute change in arterial stiffness after aerobic exercise in individuals with different body fat percentages remains unclear. This study was aimed t…
View article: Association of Cardiovascular Health Score Trajectory With Incident Myocardial Infarction in Hypertensive Patients
Association of Cardiovascular Health Score Trajectory With Incident Myocardial Infarction in Hypertensive Patients Open
Background: The association between changes in cardiovascular health score (CHS) over time and myocardial infarction (MI) risk in hypertensive patients remains unclear. Method: This was a prospective study comprising 17 374 hypertensive pa…
View article: Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study Open
Background It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact of longitudinal pat…
View article: Changes in Impaired Fasting Glucose and Borderline High Low-Density Lipoprotein-Cholesterol Status Alter the Risk of Cardiovascular Disease: A 9-Year Prospective Cohort Study
Changes in Impaired Fasting Glucose and Borderline High Low-Density Lipoprotein-Cholesterol Status Alter the Risk of Cardiovascular Disease: A 9-Year Prospective Cohort Study Open
Background We aimed to characterize the relationships of the changes in impaired fasting glucose (IFG) and borderline high low-density lipoprotein-cholesterol (LDL-C) status with cardiovascular disease (CVD). Methods A total of 36,537 part…
View article: Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort
Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort Open
Background A single measurement of the triglyceride-glucose (TyG) index, a simple and reliable surrogate marker of insulin resistance, is associated with ischemic stroke. However, evidence for an effect of a long-term elevation in TyG inde…
View article: Association of Age of Metabolic Syndrome Onset With Cardiovascular Diseases: The Kailuan Study
Association of Age of Metabolic Syndrome Onset With Cardiovascular Diseases: The Kailuan Study Open
Background Metabolic syndrome (MetS) is associated with an increased risk of incident cardiovascular diseases (CVD), but the association between the new-onset MetS at different ages and the CVD risk remain unclear. Methods This was a prosp…
View article: Epidemiological and Clinical Features, Treatment Status, and Economic Burden of Traumatic Spinal Cord Injury in China
Epidemiological and Clinical Features, Treatment Status, and Economic Burden of Traumatic Spinal Cord Injury in China Open
Background China has the largest population of traumatic spinal cord injury (TSCI), but has not yet performed a national-level study on its epidemiological and clinical features, treatment status, and economic burden. Methods A total of 14…
View article: Pathogen spectrum changes of respiratory tract infections in children in Chaoshan area under the influence of COVID-19
Pathogen spectrum changes of respiratory tract infections in children in Chaoshan area under the influence of COVID-19 Open
From 24 January 2020 to 18 May 2020, Chaoshan took measures to limit the spread of coronavirus disease 2019 (COVID-19), such as restricting public gatherings, wearing masks and suspending classes. We explored the effects of these measures …
View article: PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway
PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway Open
The present study aimed to explore the role of the PTEN/Akt/mTOR signaling pathway in the neurite outgrowth and apoptosis of cortical neurons. Cortical neurons were seeded on or adjacent to chondroitin sulfate proteoglycans. The length, nu…
View article: Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR
Differential thermostability and response to cystic fibrosis transmembrane conductance regulator potentiators of human and mouse F508del-CFTR Open
Cross-species comparative studies have highlighted differences between human and mouse cystic fibrosis transmembrane conductance regulator (CFTR), the epithelial Cl − channel defective in cystic fibrosis (CF). Here, we compare the impact o…
View article: Potentiation of the cystic fibrosis transmembrane conductance regulator Cl<sup>−</sup>channel by ivacaftor is temperature independent
Potentiation of the cystic fibrosis transmembrane conductance regulator Cl<sup>−</sup>channel by ivacaftor is temperature independent Open
Ivacaftor is the first drug to target directly defects in the cystic fibrosis transmembrane conductance regulator (CFTR), which causes cystic fibrosis (CF). To understand better how ivacaftor potentiates CFTR channel gating, here we invest…
View article: Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators
Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators Open
Treatment of individuals with cystic fibrosis (CF) has been transformed by small molecule therapies that target select pathogenic variants in the CF transmembrane conductance regulator (CFTR). To expand treatment eligibility, we stably exp…