Zhixiu Xu
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View article: Association between hemoglobin-to-red blood cell distribution width ratio and cognitive function in older US adults: a cross-sectional study based on the NHANES 2011–2014
Association between hemoglobin-to-red blood cell distribution width ratio and cognitive function in older US adults: a cross-sectional study based on the NHANES 2011–2014 Open
Introduction The hemoglobin-to-red blood cell distribution width ratio (HRR) is acknowledged as a promising new prognostic biomarker. Nevertheless, investigations into its connection with cognitive function have yielded unclear results. Ai…
View article: The prevalence, diagnostic accuracy and genotype-phenotype correlation of GNAS mutations in fibrous dysplasia: a meta-analysis
The prevalence, diagnostic accuracy and genotype-phenotype correlation of GNAS mutations in fibrous dysplasia: a meta-analysis Open
Background There is inconsistent evidence regarding the accuracy of GNAS mutations identification for the diagnosis of FD/MAS. This study was performed to estimate the prevalence and diagnostic accuracy of GNAS mutations detection and to p…
View article: The effect of CX3CL1/ CX3CR1 signal axis on microglia in central nervous system diseases
The effect of CX3CL1/ CX3CR1 signal axis on microglia in central nervous system diseases Open
CX3C chemokine ligand 1 (CX3CL1), a unique member of the CX3C family, is most widely expressed in endothelial cells and neurons. Its specific receptor is CX3CR1, which is mainly expressed in central nervous system (CNS) microglia. CX3CL1 h…
View article: Is Matrix Metalloproteinase-9 Associated with Post-Stroke Cognitive Impairment or Dementia?
Is Matrix Metalloproteinase-9 Associated with Post-Stroke Cognitive Impairment or Dementia? Open
Background: Matrix metalloproteinase-9 (MMP-9) is a significant protease required for synaptic plasticity, learning, and memory. Yet, the role of MMP-9 in the occurrence and development of cognitive decline after ischemic stroke is not ful…
View article: Role of narrative medical education in cultivating empathy of general practitioners
Role of narrative medical education in cultivating empathy of general practitioners Open
Objective To explore the role of narrative medicine in empathy training in standardized training of general practitioners. Methods A total of 230 general practitioners under neurology training among the 2018-2020 residents in the First Aff…
View article: Fibroblast growth factor receptor 1 antagonism attenuates lipopolysaccharide‑induced activation of hepatic stellate cells via suppressing inflammation
Fibroblast growth factor receptor 1 antagonism attenuates lipopolysaccharide‑induced activation of hepatic stellate cells via suppressing inflammation Open
Activated hepatic stellate cells (HSCs) serve key roles in hepatic fibrosis by producing excessive extracellular matrix (ECM) components. Lipopolysaccharide (LPS) has been found to be associated with hepatic fibrogenesis through direct int…
View article: Increased intracranial pressure in Guillain–Barré syndrome
Increased intracranial pressure in Guillain–Barré syndrome Open
In GBS patients who have a relapsing course and develop papilledema with possible immunological disturbance, an accurate early diagnosis in conjunction with the prompt initiation of immunotherapy may improve clinical symptoms and the progn…
View article: Retrospective study of survival in human papillomavirus-negative oropharyngeal squamous cell carcinoma treated with primary surgery and associated prognostic factors
Retrospective study of survival in human papillomavirus-negative oropharyngeal squamous cell carcinoma treated with primary surgery and associated prognostic factors Open
The outcomes of the surgical treatment of oropharyngeal squamous cell carcinoma were acceptable, and N-stage, adjuvant radiotherapy were identified as prognostic factors.
View article: The Effect of MSCs Derived from the Human Umbilical Cord Transduced by Fibroblast Growth Factor‐20 on Parkinson’s Disease
The Effect of MSCs Derived from the Human Umbilical Cord Transduced by Fibroblast Growth Factor‐20 on Parkinson’s Disease Open
Cell therapy is a potential therapeutic approach for Parkinson’s disease (PD). Mesenchymal stem cells derived from the human umbilical cord (hUC‐MSCs) give priority to PD patients because of multiple advantages. The appropriate gene transd…
View article: Therapeutic Effects of CUR-Activated Human Umbilical Cord Mesenchymal Stem Cells on 1-Methyl-4-phenylpyridine-Induced Parkinson’s Disease Cell Model
Therapeutic Effects of CUR-Activated Human Umbilical Cord Mesenchymal Stem Cells on 1-Methyl-4-phenylpyridine-Induced Parkinson’s Disease Cell Model Open
The purpose of this study is to evaluate the therapeutic effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSC) activated by curcumin (CUR) on PC12 cells induced by 1-methyl-4-phenylpyridinium ion (MPP+), a cell model of …