Zhiyou Zong
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View article: Boosting Enzyme Activity in Biomass Conversion by Modulating the Hydrolysis Process of Cellobiohydrolases
Boosting Enzyme Activity in Biomass Conversion by Modulating the Hydrolysis Process of Cellobiohydrolases Open
Cellobiohydrolases (CBHs) are the most significant cellulose-degrading enzymes, the performance of which determines the cost-effective utilization of renewable lignocellulosic resources. Most engineering strategies for improving CBH hydrol…
View article: A double-switch pHLIP system enables selective enrichment of circulating tumor microenvironment-derived extracellular vesicles
A double-switch pHLIP system enables selective enrichment of circulating tumor microenvironment-derived extracellular vesicles Open
Circulating tumor microenvironment-derived extracellular vesicles (cTME-EVs) are gaining considerable traction in cancer research and liquid biopsy. However, the study of cTME-EVs is largely limited by the dearth of a general isolation tec…
View article: Achieving Ultrasensitive Chromogenic Probes for Rapid, Direct Detection of Carbapenemase-Producing Bacteria in Sputum
Achieving Ultrasensitive Chromogenic Probes for Rapid, Direct Detection of Carbapenemase-Producing Bacteria in Sputum Open
Carbapenemase-producing bacteria (CPB) stand as the most dangerous "superbugs" in the clinic. Rapid point-of-care (POC) detection of CPB in clinical samples is key to timely and effective infection management. We herein report the first ul…
View article: Flexible linker modulates the binding affinity of the TP901‐1 CI phage repressor to DNA
Flexible linker modulates the binding affinity of the TP901‐1 CI phage repressor to DNA Open
Temperate bacteriophages can switch between two life cycles following infection of a host bacterium: the lytic or lysogenic life cycle. The choice between these is controlled by a bistable genetic switch. We investigated the genetic switch…
View article: Insight into the Underlying Synergy between Exo–Lytic Cellulases
Insight into the Underlying Synergy between Exo–Lytic Cellulases Open
Lignocellulosic biomass can be converted into biofuels and biochemicals, through a synergetic degradation by cellulases. The underlying cooperative mechanism is of paramount importance for the development of efficient enzyme cocktails. The…