Zhongjie Lu
YOU?
Author Swipe
View article: An isodose‐constrained automatic treatment planning strategy using a multicriteria predicted dose rating
An isodose‐constrained automatic treatment planning strategy using a multicriteria predicted dose rating Open
Background Previous knowledge‐based planning studies have demonstrated the feasibility of predicting three‐dimensional photon dose distributions and subsequently generating treatment plans. The steepness of dose fall‐off represents a criti…
View article: A physics-informed deep learning model for predicting beam dose distribution of intensity-modulated radiation therapy treatment plans
A physics-informed deep learning model for predicting beam dose distribution of intensity-modulated radiation therapy treatment plans Open
This study proposes a physics-informed deep learning network specifically for the task of beam dose prediction. Additionally, this study addresses the interpretability challenges in deep learning models by employing a crosshair sampling sc…
View article: Efficacy of digital therapeutics for perioperative management in patients with lung cancer: a randomized controlled trial
Efficacy of digital therapeutics for perioperative management in patients with lung cancer: a randomized controlled trial Open
View article: Establishing a prognostic scoring system and exploring prognostic value of examined lymph node numbers for stage I non-small cell lung cancer: a retrospective study of Surveillance, Epidemiology, and End Results (SEER) database and a Chinese cohort
Establishing a prognostic scoring system and exploring prognostic value of examined lymph node numbers for stage I non-small cell lung cancer: a retrospective study of Surveillance, Epidemiology, and End Results (SEER) database and a Chinese cohort Open
This prognostic scoring system will anticipate the prognosis of stage I NSCLC patients after radical treatment, thereby offering individualized treatment recommendations for both clinicians and patients. A minimum of 10 ELNs during lobecto…
View article: The cardiovascular system at high altitude: A bibliometric and visualization analysis
The cardiovascular system at high altitude: A bibliometric and visualization analysis Open
BACKGROUND When exposed to high-altitude environments, the cardiovascular system undergoes various changes, the performance and mechanisms of which remain controversial. AIM To summarize the latest research advancements and hot research po…
View article: A Cross-cultural Comparative Study between Chinese and Japanese Preschool Educators’ Use of Mental State Language in Interactions With Children
A Cross-cultural Comparative Study between Chinese and Japanese Preschool Educators’ Use of Mental State Language in Interactions With Children Open
Mental state language (MSL) is a language used to describe individual internal states including one’s desire, emotion, perception and cognition. This study compared Chinese and Japanese preschool educators’ use of MSL in interactions with …
View article: Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma?
Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma? Open
View article: Telepresence Observation for Kindergarten Classroom Rating: A Pilot Study
Telepresence Observation for Kindergarten Classroom Rating: A Pilot Study Open
Quality evaluation of kindergarten classrooms is important for promoting teachers’ competencies and ensuring high-quality education. Currently, human observers physically visit kindergartens and provide assessments by observing classroom a…
View article: A Convenient and Effective Preoxygenation Technique for Prolonging Deep Inspiration Breath-Hold Duration With a Venturi Mask With a 50% Oxygen Concentration
A Convenient and Effective Preoxygenation Technique for Prolonging Deep Inspiration Breath-Hold Duration With a Venturi Mask With a 50% Oxygen Concentration Open
Preoxygenation with a 50% oxygen concentration for 15 minutes effectively prolongs the duration of 6 cycles of DIBH both in healthy volunteers and RT patients. The utilization of a Venturi mask to deliver 50% oxygen concentration provides …
View article: Experimental and numerical study on the heat transfer and flow characteristics of micro-gap chip with longitudinal vortex generator array
Experimental and numerical study on the heat transfer and flow characteristics of micro-gap chip with longitudinal vortex generator array Open
The longitudinal vortex generators (LVGs) are introduced in the 3D stacked chip micro gaps to enhance heat transfer. Experimental and numerical tests on the performance of 3D stacked chip with and without LVGs in the gap are conducted, and…
View article: Figure S2 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S2 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
In vitro cytotoxicity of nanodrugs against human breast cancer MDA-MB-231 cells and human colorectal carcinoma LoVo cells
View article: Figure S9-S14 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S9-S14 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Histological analysis of tumors and major organs
View article: Figure S1 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S1 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
The morphology of SNMs and PEGylated SNMs determined by TEM and DLS
View article: Figure S4 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S4 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Systemic toxicity of pSNMs in healthy ICR mice
View article: Figure S2 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S2 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
In vitro cytotoxicity of nanodrugs against human breast cancer MDA-MB-231 cells and human colorectal carcinoma LoVo cells
View article: Supplementary Material and Methods from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Supplementary Material and Methods from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Description of synthesis of compounds, additional experiments and procedures, and Table S1
View article: Figure S4 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S4 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Systemic toxicity of pSNMs in healthy ICR mice
View article: Figure S7-S8 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S7-S8 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Antitumor efficacy assessed in MDA-MB-231 and DU145 tumor-bearing mouse models
View article: Figure S5-S6 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S5-S6 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
In vivo drug plasma concentration-time profile and drug tissue biodistribution
View article: Figure S1 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S1 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
The morphology of SNMs and PEGylated SNMs determined by TEM and DLS
View article: Figure S5-S6 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S5-S6 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
In vivo drug plasma concentration-time profile and drug tissue biodistribution
View article: Figure S9-S14 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S9-S14 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Histological analysis of tumors and major organs
View article: Figure S3 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S3 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Hydrolysis of prodrugs under different conditions analyzed by HPLC
View article: Data from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Data from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
The therapeutic index for chemotherapeutic drugs is determined in part by systemic toxicity, so strategies for dose intensification to improve efficacy must also address tolerability. In addressing this issue, we have investigated a novel …
View article: Supplementary Material and Methods from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Supplementary Material and Methods from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Description of synthesis of compounds, additional experiments and procedures, and Table S1
View article: Figure S7-S8 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S7-S8 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Antitumor efficacy assessed in MDA-MB-231 and DU145 tumor-bearing mouse models
View article: Figure S3 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Figure S3 from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
Hydrolysis of prodrugs under different conditions analyzed by HPLC
View article: Data from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity
Data from New Generation Nanomedicines Constructed from Self-Assembling Small-Molecule Prodrugs Alleviate Cancer Drug Toxicity Open
The therapeutic index for chemotherapeutic drugs is determined in part by systemic toxicity, so strategies for dose intensification to improve efficacy must also address tolerability. In addressing this issue, we have investigated a novel …
View article: Suicide rates among patients with first and second primary cancer
Suicide rates among patients with first and second primary cancer Open
Aims With advancements in cancer treatments, the survival rates of patients with their first primary cancer (FPC) have increased, resulting in a rise in the number of patients with second primary cancer (SPC). However, there has been no as…
View article: Comprehensive and Clinically Accurate Head and Neck Organs at Risk Delineation via Stratified Deep Learning: A Large-scale Multi-Institutional Study
Comprehensive and Clinically Accurate Head and Neck Organs at Risk Delineation via Stratified Deep Learning: A Large-scale Multi-Institutional Study Open
Accurate organ at risk (OAR) segmentation is critical to reduce the radiotherapy post-treatment complications. Consensus guidelines recommend a set of more than 40 OARs in the head and neck (H&N) region, however, due to the predictable pro…