Zhongping Duan
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View article: Identification of specific molecular markers in severe heatstroke using transcriptomics techniques
Identification of specific molecular markers in severe heatstroke using transcriptomics techniques Open
This study provides comparative transcriptomic evidence distinguishing heatstroke from fever. The identified markers, particularly Hspa1a, Hspa1b, Cyp7a1, Arrdc3, and G6pc, may serve as potential forensic indicators for differentiating hyp…
View article: Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis
Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis Open
Thrombocytopenia in cirrhosis presents significant challenges in clinical practice. To help clinicians rapidly understand and standardize the diagnosis and treatment of this condition, the Liver Fibrosis, Cirrhosis, and Portal Hypertension…
View article: Corrigendum to “A HRG novel mutation associated with idiopathic portal hypertension: Case report and literature review” [iLIVER 1 (2022) 90–95]
Corrigendum to “A HRG novel mutation associated with idiopathic portal hypertension: Case report and literature review” [iLIVER 1 (2022) 90–95] Open
View article: The Perylenediimide‐Based Cathode Interfacial Materials can “Kill” Nonfullerene Acceptors ITIC/Y6
The Perylenediimide‐Based Cathode Interfacial Materials can “Kill” Nonfullerene Acceptors ITIC/Y6 Open
High‐performance interfacial materials and nonfullerene electron acceptors (NFAs) play pivotal function in organic solar cells (OSCs). The representative cathode interfacial materials such as amine‐functionalized perylene‐diimide (PDINN), …
View article: Correction: Oxidative and Endoplasmic Reticulum Stress Mediate Testicular Injury in a Rat Model of Varicocele
Correction: Oxidative and Endoplasmic Reticulum Stress Mediate Testicular Injury in a Rat Model of Varicocele Open
View article: Dynamic skeletal muscle loss and its predictive role on 90-day mortality in patients with acute-on-chronic liver failure
Dynamic skeletal muscle loss and its predictive role on 90-day mortality in patients with acute-on-chronic liver failure Open
Background Low skeletal muscle mass is an independent risk factor for increased mortality in patients with acute-on-chronic liver failure (ACLF). However, no study has evaluated the temporal changes in muscle mass during the course of ACLF…
View article: Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis (2024)
Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis (2024) Open
With progress in basic and clinical research on hepatic encephalopathy in cirrhosis worldwide, the Chinese Society of Hepatology of the Chinese Medical Association has invited experts in relevant fields to revise the 2018 "Chinese Guidelin…
View article: Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia
Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia Open
View article: Global Burden of Wilson Disease: A Comprehensive Evidence Synthesis
Global Burden of Wilson Disease: A Comprehensive Evidence Synthesis Open
View article: Association of myosteatosis with short-term outcomes in patients with acute-on-chronic liver failure
Association of myosteatosis with short-term outcomes in patients with acute-on-chronic liver failure Open
View article: The value of dynamic changes in FT3 level for predicting 90-day prognosis of HBV-ACLF patients
The value of dynamic changes in FT3 level for predicting 90-day prognosis of HBV-ACLF patients Open
View article: Beyond waste: understanding urine’s potential in precision medicine
Beyond waste: understanding urine’s potential in precision medicine Open
View article: Impact of Onset Time, Number, Type, and Sequence of Extrahepatic Organ Failure on Prognosis of Acute-on-chronic Liver Failure
Impact of Onset Time, Number, Type, and Sequence of Extrahepatic Organ Failure on Prognosis of Acute-on-chronic Liver Failure Open
The mortality of ACLF patients was determined by the number and type, but not the onset time and sequence of EHOF. Risk stratification applicable to clinical practice was established.
View article: Precision nephrotoxicity testing using 3D in vitro models
Precision nephrotoxicity testing using 3D in vitro models Open
View article: Corrigendum: Programmed cell death and lipid metabolism of macrophages in NAFLD
Corrigendum: Programmed cell death and lipid metabolism of macrophages in NAFLD Open
[This corrects the article DOI: 10.3389/fimmu.2023.1118449.].
View article: Consensus on the tertiary prevention of primary liver cancer
Consensus on the tertiary prevention of primary liver cancer Open
To effectively prevent recurrence, improve the prognosis and increase the survival rate of primary liver cancer (PLC) patients with radical cure, the Chinese Society of Hepatology, Chinese Medical Association, invited clinical experts and …
View article: Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence
Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence Open
View article: Comparison of NK cell subsets, receptors and functions induced by radiofrequency ablation and microwave ablation in HBV-associated primary hepatocellular carcinoma
Comparison of NK cell subsets, receptors and functions induced by radiofrequency ablation and microwave ablation in HBV-associated primary hepatocellular carcinoma Open
Background Topical therapy has been shown to induce an immune response in patients with hepatocellular carcinoma (HCC). In this study, a prospective parallel group control experiment was conducted to compare the differences between radiofr…
View article: Guidelines on the Diagnosis and Management of Primary Biliary Cholangitis (2021)
Guidelines on the Diagnosis and Management of Primary Biliary Cholangitis (2021) Open
In 2015, the Chinese Society of Hepatology and the Chinese Society of Gastroenterology published a consensus on primary biliary cholangitis (PBC). In the past years, numerous clinical studies have been published in the field of PBC. To gui…
View article: The novel hepatoprotective mechanisms of silibinin-phospholipid complex against d-GalN/LPS-induced acute liver injury
The novel hepatoprotective mechanisms of silibinin-phospholipid complex against d-GalN/LPS-induced acute liver injury Open
SPC alleviates acute liver injury through up-regulating the expression of miR-223-3p. MiR-223-3p further promotes M2-like macrophage activation and the targeted inhibition of necroptosis and necroinflammation. Our findings provide novel in…
View article: Programmed cell death and lipid metabolism of macrophages in NAFLD
Programmed cell death and lipid metabolism of macrophages in NAFLD Open
Non-alcoholic fatty liver disease (NAFLD) has now become the leading chronic liver disease worldwide with lifestyle changes. This may lead to NAFLD becoming the leading cause of end-stage liver disease in the future. To date, there are sti…
View article: Analysis of Efficacy and Safety of Small-Volume-Plasma Artificial Liver Model in the Treatment of Acute-On-Chronic Liver Failure
Analysis of Efficacy and Safety of Small-Volume-Plasma Artificial Liver Model in the Treatment of Acute-On-Chronic Liver Failure Open
To explore the efficacy and safety of a small-volume-plasma artificial liver support system (ALSS) in the treatment of acute-on-chronic liver failure (ACLF). A retrospective analysis was performed. All ACLF patients received ALSS of plasma…
View article: Galectin-3 critically mediates the hepatoprotection conferred by M2-like macrophages in ACLF by inhibiting pyroptosis but not necroptosis signalling
Galectin-3 critically mediates the hepatoprotection conferred by M2-like macrophages in ACLF by inhibiting pyroptosis but not necroptosis signalling Open
We previously documented that M2-like macrophages exert a hepatoprotective effect in acute-on-chronic liver failure (ACLF) by inhibiting necroptosis signalling. Nevertheless, the molecular mechanism behind this hepatoprotection still needs…
View article: Kuhuang injection exerts a protective effect by activating PPAR-γ in an <i>in vitro</i> model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering
Kuhuang injection exerts a protective effect by activating PPAR-γ in an <i>in vitro</i> model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering Open
Kuhuang could alleviate CPZ-induced cholestatic liver injury by activating PPARγ to reduce oxidative stress. Applying kuhuang for the treatment of CPZ-induced liver injury could be suggested.
View article: Current status of and barriers to the treatment of advanced-stage liver cancer in China: a questionnaire-based study from the perspective of doctors
Current status of and barriers to the treatment of advanced-stage liver cancer in China: a questionnaire-based study from the perspective of doctors Open
Background Liver cancer is a severe public health problem worldwide, and it creates a relatively higher disease burden in China than in the Western world. Despite achieving notable progress in China, potential differences in some aspects o…
View article: Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis Open
Objective Metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) are the leading chronic diseases worldwide. There are still many controversies about the association between serum bilirubin and MetS or NAFLD. This study ai…
View article: Expert Consensus on Diagnosis and Treatment of End-Stage Liver Disease Complicated with Infections
Expert Consensus on Diagnosis and Treatment of End-Stage Liver Disease Complicated with Infections Open
End-stage liver disease (ESLD) is a life-threatening clinical syndrome that markedly increases mortality in patients with infections. In patients with ESLD, infections can induce or aggravate the occurrence of liver decompensation. Consequ…
View article: Correlation between dynamic changes in free triiodothyronine levels and 90-day prognosis in patients with HBV-related acute-on-chronic liver failure
Correlation between dynamic changes in free triiodothyronine levels and 90-day prognosis in patients with HBV-related acute-on-chronic liver failure Open
View article: Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis
Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis Open
Introduction Acute liver inflammatory reactions contribute to many health problems; thus, it is critical to understand the underlying pathogenic mechanisms of acute hepatitis. In this study, an experimental in vivo model of concanavalin A …
View article: A HRG novel mutation associated with idiopathic portal hypertension: Case report and literature review
A HRG novel mutation associated with idiopathic portal hypertension: Case report and literature review Open