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View article: Tetrathiomolybdate alleviates osteoporosis by activating the PI3K/Akt signaling axis
Tetrathiomolybdate alleviates osteoporosis by activating the PI3K/Akt signaling axis Open
To investigate the role and possible mechanisms of tetrathiomolybdate (TTM) in ovariectomy (OVX)-induced osteoporotic mice. Eighteen 12-week-old C57BL/6 female mice were randomized into three groups: sham-operated group (Sham group, n = 6)…
View article: IRE1 RNase controls CD95-mediated cell death
IRE1 RNase controls CD95-mediated cell death Open
Signalling by the Unfolded Protein Response (UPR) or by the Death Receptors (DR) represents cellular stress pathways frequently activated towards pro-tumoral outputs in cancer. Experimental evidence has highlighted functional links between…