Zhouqiao Wu
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View article: A Novel TRG-N Prognostic Classification System for Esophageal Cancer Undergoing Neoadjuvant Therapy Followed by Esophagectomy
A Novel TRG-N Prognostic Classification System for Esophageal Cancer Undergoing Neoadjuvant Therapy Followed by Esophagectomy Open
Objective: To develop a new prognostic classification system centered on tumor regression grade (TRG) and ypN stage that can effectively stratify overall survival (OS) of esophageal cancer patients undergoing neoadjuvant therapy (NAT) foll…
View article: Association of waiting time from diagnosis to neoadjuvant chemoradiotherapy on interval distant metastases in esophageal cancer patients: A study based on the Netherlands cancer registry
Association of waiting time from diagnosis to neoadjuvant chemoradiotherapy on interval distant metastases in esophageal cancer patients: A study based on the Netherlands cancer registry Open
A longer waiting time from diagnosis to the initiation of (n)CRT was associated with a higher risk of interval metastases, but not with an increased risk of post-(n)CRT short-term metastases or worse OS.
View article: Mechanisms of anastomotic leakage in colorectal cancer surgery: unraveling the roles of inflammation, immunity, and microbiota – a narrative review
Mechanisms of anastomotic leakage in colorectal cancer surgery: unraveling the roles of inflammation, immunity, and microbiota – a narrative review Open
Anastomotic leakage (AL) is a major complication of colorectal surgery that can lead to abdominal infection and systemic inflammatory response. Meanwhile, the microbiota and immune microenvironment at the anastomosis are closely related to…
View article: Surgical quality and health utilization of gastric cancer surgery in China: a post hoc analysis of the Prevalence of Abdominal Complications After Gastroenterological Surgery study
Surgical quality and health utilization of gastric cancer surgery in China: a post hoc analysis of the Prevalence of Abdominal Complications After Gastroenterological Surgery study Open
Objectives This study aimed to assess the surgical quality, safety, and healthcare utilization associated with gastric cancer surgery in China, using international studies for benchmarking. Design A prospective registered study was conduct…
View article: C-Reactive Protein in Peritoneal Fluid for Predicting Anastomotic Leakage After Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis
C-Reactive Protein in Peritoneal Fluid for Predicting Anastomotic Leakage After Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis Open
Background: Anastomotic leakage (AL) is a serious and potentially fatal complication that can occur after colorectal cancer (CRC) surgery, and it significantly affects patient recovery and increases morbidity. While serum C-reactive protei…
View article: The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the <scp>PD</scp> ‐ <scp>L</scp> 1/ <scp>PD</scp> ‐1 axis
The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the <span>PD</span> ‐ <span>L</span> 1/ <span>PD</span> ‐1 axis Open
Gastric cancer (GC) is the third leading cause of cancer‐related deaths worldwide, with gastrectomy being the primary treatment option. Sepsis, a systemic inflammatory response to infection, may influence tumor growth by creating an immuno…
View article: Machine learning-based prediction model for postoperative complications in gastric and colorectal cancer: A prospective nationwide multi-center study
Machine learning-based prediction model for postoperative complications in gastric and colorectal cancer: A prospective nationwide multi-center study Open
This model demonstrated good predictive performance for overall and infectious complications based on the multi-center database, supporting clinical decision-making and personalized treatment strategies.
View article: Comparison between AJCC 8th edition gastric and esophageal ypTNM classification system in Siewert II esophagogastric junction adenocarcinomas: A retrospective study based on Eastern and Western Data
Comparison between AJCC 8th edition gastric and esophageal ypTNM classification system in Siewert II esophagogastric junction adenocarcinomas: A retrospective study based on Eastern and Western Data Open
The AJCC 8th edition ypTNM prognostic classification systems for esophageal and gastric cancer demonstrated no difference in predicting OS for patients with Siewert II adenocarcinomas both in the Western and Eastern data. The ypTNM-GC, wit…
View article: Impact of Preoperative Time Intervals for Neoadjuvant Chemoradiotherapy on Short-term Postoperative Outcomes of Esophageal Cancer Surgery
Impact of Preoperative Time Intervals for Neoadjuvant Chemoradiotherapy on Short-term Postoperative Outcomes of Esophageal Cancer Surgery Open
Objective: To clarify the impact of the preoperative time intervals on short-term postoperative and pathologic outcomes in patients with esophageal cancer who underwent neoadjuvant chemoradiotherapy (nCRT) followed by esophagectomy. Backgr…
View article: Feasibility and long-term survival of proximal gastrectomy after neoadjuvant therapy for locally advanced proximal gastric cancer: A propensity-score-matched analysis
Feasibility and long-term survival of proximal gastrectomy after neoadjuvant therapy for locally advanced proximal gastric cancer: A propensity-score-matched analysis Open
Background: Neoadjuvant therapy enhances the possibility of achieving radical resection and improves the prognosis for locally advanced gastric cancer (GC). However, there is a lack of evidence regarding the optimal extent of resection for…
View article: Discontinuation of neoadjuvant therapy does not influence postoperative short-term outcomes in elderly patients (≥ 70 years) with resectable gastric cancer: a population-based study from the dutch upper gastrointestinal cancer audit (DUCA) data
Discontinuation of neoadjuvant therapy does not influence postoperative short-term outcomes in elderly patients (≥ 70 years) with resectable gastric cancer: a population-based study from the dutch upper gastrointestinal cancer audit (DUCA) data Open
View article: Comparison of uncut Roux-en-Y anastomosis and Billroth-II with Braun anastomosis after distal gastrectomy
Comparison of uncut Roux-en-Y anastomosis and Billroth-II with Braun anastomosis after distal gastrectomy Open
Background This study aimed to compare the clinical outcomes and patient benefits of uncut Roux-en-Y (URY) anastomosis and Billroth-II with Braun (BB) anastomosis after distal gastrectomy. Methods We retrospectively reviewed the data of pa…
View article: Label‐Free Virtual Peritoneal Lavage Cytology via Deep‐Learning‐Assisted Single‐Color Stimulated Raman Scattering Microscopy
Label‐Free Virtual Peritoneal Lavage Cytology via Deep‐Learning‐Assisted Single‐Color Stimulated Raman Scattering Microscopy Open
Clinical guidelines for gastric cancer treatment recommend intraoperative peritoneal lavage cytology to detect free cancer cells. Patients with positive cytology require neoadjuvant chemotherapy instead of instant resection, and conversion…
View article: Safety and short-term outcomes of a modified valvuloplastic esophagogastrostomy versus gastric tube anastomosis after laparoscopy-assisted proximal gastrectomy: a retrospective cohort study
Safety and short-term outcomes of a modified valvuloplastic esophagogastrostomy versus gastric tube anastomosis after laparoscopy-assisted proximal gastrectomy: a retrospective cohort study Open
View article: Label-free virtual peritoneal lavage cytology via deep-learning-assisted single-color stimulated Raman scattering microscopy
Label-free virtual peritoneal lavage cytology via deep-learning-assisted single-color stimulated Raman scattering microscopy Open
Clinical guidelines for gastric cancer treatment recommend intraoperative peritoneal lavage cytology to detect free cancer cells. Patients with positive cytology require neoadjuvant chemotherapy instead of instant resection and conversion …
View article: Genomic characterization of peritoneal lavage cytology-positive gastric cancer
Genomic characterization of peritoneal lavage cytology-positive gastric cancer Open
There might not be distinct differences between CY1 and CY0, and CY1 might represent the progression of CY0 gastric cancer rather than constituting an independent subtype. This genomic analysis will thus provide key molecular insights into…
View article: Machine Learning-Based Prediction Model for Postoperative Complications in Gastric and Colorectal Cancer: A Prospective Nationwide Multi-Center Study
Machine Learning-Based Prediction Model for Postoperative Complications in Gastric and Colorectal Cancer: A Prospective Nationwide Multi-Center Study Open
View article: Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI‐Assisted Stimulated Raman Molecular Cytology
Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI‐Assisted Stimulated Raman Molecular Cytology Open
Peritoneal metastasis (PM) is the mostcommon form of distant metastasis and one of the leading causes of death in gastriccancer (GC). For locally advanced GC, clinical guidelines recommend peritoneal lavage cytology for intraoperative PM d…
View article: Characterization of glycometabolism and tumor immune microenvironment for predicting clinical outcomes in gastric cancer
Characterization of glycometabolism and tumor immune microenvironment for predicting clinical outcomes in gastric cancer Open
View article: Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI-assisted Stimulated Raman Cytology
Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI-assisted Stimulated Raman Cytology Open
Peritoneal metastasis (PM) is the most common form of distant metastasis and one of the leading causes of death in gastric cancer (GC). For locally advanced GC, clinical guidelines recommend peritoneal lavage cytology for intraoperative PM…
View article: The expression panel of CXCL9, GBP5, and IFNG is a potential pan-cancer biomarker to predict immunotherapy response.
The expression panel of CXCL9, GBP5, and IFNG is a potential pan-cancer biomarker to predict immunotherapy response. Open
The expression panel of CXCL9, IFNG, and GBP5 can potentially be a pan-cancer biomarker for predicting immunotherapy response.
View article: The significance of time interval between perioperative SOX/XELOX chemotherapy and clinical decision model in gastric cancer
The significance of time interval between perioperative SOX/XELOX chemotherapy and clinical decision model in gastric cancer Open
Introduction To investigate the influences of time interval between multimodality therapies on survival for locally advanced gastric cancer (LAGC) patients, 627 patients were included in a retrospective study, and 350 who received neoadjuv…
View article: Optimized tools and timing of response reassessment after neoadjuvant chemoradiation in rectal cancer
Optimized tools and timing of response reassessment after neoadjuvant chemoradiation in rectal cancer Open
View article: Diverting Stoma Prevents Symptomatic Anastomotic Leakage but Not Intra-abdominal Infection After Low Anterior Resection
Diverting Stoma Prevents Symptomatic Anastomotic Leakage but Not Intra-abdominal Infection After Low Anterior Resection Open
Purpose Anastomotic leakage (AL) remains a devastating complication following low anterior resection (LAR) for left colorectal cancer. Previous studies have identified several factors to predict it. However, evidence seems conflicting, esp…
View article: Nomogram for predicting the prognosis of tumor patients with sepsis after gastrointestinal surgery
Nomogram for predicting the prognosis of tumor patients with sepsis after gastrointestinal surgery Open
The nomogram based on these five factors (tumor type, septic shock, number of lymphocytes, serum creatinine, and total operation times) could accurately predict the prognosis of tumor patients with sepsis after gastrointestinal surgery.
View article: Early diagnosis of anastomotic leakage after colorectal cancer surgery using an inflammatory factors-based score system
Early diagnosis of anastomotic leakage after colorectal cancer surgery using an inflammatory factors-based score system Open
Background Anastomotic leakage (AL) is a severe complication after colorectal surgery. This study aimed to investigate a method for the early diagnosis of AL after surgical resection by analysing inflammatory factors (IFs) in peritoneal dr…
View article: Correlative Analysis Between Adverse Events of Preoperative Chemotherapy and Postoperative Complications of Gastric Cancer
Correlative Analysis Between Adverse Events of Preoperative Chemotherapy and Postoperative Complications of Gastric Cancer Open
Background and Objectives: This study aims to explore the safety of preoperative chemotherapy and clarify whether preoperative chemotherapy with oxaliplatin + S-1 (SOX) regimen and its adverse events are associated with higher risks of pos…
View article: Utilizing local anti-cancer treatment and online medical service during the COVID-19 pandemic
Utilizing local anti-cancer treatment and online medical service during the COVID-19 pandemic Open
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View article: ASO Visual Abstract: Early Diagnosis of Anastomotic Leakage After Gastric Cancer Surgery via Analysis of Inflammatory Factors in Abdominal Drainage
ASO Visual Abstract: Early Diagnosis of Anastomotic Leakage After Gastric Cancer Surgery via Analysis of Inflammatory Factors in Abdominal Drainage Open
View article: Prognostic predictors in patients with sepsis after gastrointestinal tumor surgery: A retrospective study
Prognostic predictors in patients with sepsis after gastrointestinal tumor surgery: A retrospective study Open
Lactic acid and SOFA score within 24 h after ICU admission are independent risk predictors of the prognosis of sepsis after gastrointestinal tumor surgery. SOFA score combined with BMI and lactic acid might have good predictive value.