Explanipedia

The reproductive toxicity of aggregation-induced emission nanoparticles on mouse ovarian function Open

Yibin Zhang, Nan Qiao, Yihang Jiang, Miaozhuang Fan, Wenguang Zhang , et al. · 2025

Wireless charging LED mediated type I photodynamic therapy of breast cancer using NIR AIE photosensitizer Open

Chengbin Yang, Shiqi Tang, Qiqi Liu, Miaozhuang Fan, Wenguang Zhang , et al. · 2025

Due to limited light penetration and dependence on oxygen, photodynamic therapy (PDT) is typically restricted to treating shallow tissues. Developing strategies to overcome these limitations and effectively using PDT for tumor treatment is…

Correction to “Overcome the “Buckets Effect”: Integration of AIEgens into Proteins for Fluorescence‐Enhanced Two‐Photon Imaging” Open

Miaozhuang Fan, Zhengzheng Li, Gang Feng, Yibing Zhang, Wenguang Zhang , et al. · 2024

Overcome the "Buckets Effect": Integration of AIEgens into Proteins for Fluorescence-Enhanced Two-Photon Imaging. Adv. Healthcare Mater. 2023, 12, 2301568, https://doi.org/10.1002/adhm.202301568 In the section 2.5 "Toxicity Assessment of M…

High-performance pyrite nano-catalyst driven photothermal/chemodynamic synergistic therapy for Osteosarcoma Open

Meirong Li, Minghua Wang, Junfeng Huang, Shiqi Tang, Jingyu Yang , et al. · 2024

Conjugated Oligoelectrolyte with DNA Affinity for Enhanced Nuclear Imaging and Precise DNA Quantification Open

Xinmeng Zhang, Cheng Zhou, Jianxun Hou, Gang Feng, Zhourui Xu , et al. · 2024

Precise DNA quantification and nuclear imaging are pivotal for clinical testing, pathological diagnosis, and drug development. The detection and localization of mitochondrial DNA serve as crucial indicators of cellular health. We introduce…

Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II Open

Xiangwei Lin, Zhourui Xu, Jiangao Li, Hongji Shi, Zhenyu Fu , et al. · 2023

Comparison of the penetration depth in mouse brain in vivo through 3PF imaging using AIE nanoparticle labeling and THG imaging within the 1700 nm window Open

Yingxian Zhang, Jincheng Zhong, Hui Cheng, Jie Huang, Zhenhui Li , et al. · 2023

Herein, we systematically studied 3PF imaging and THG imaging in living mice at different excitation wavelengths within the 1700 nm window, thus exploring the optimal wavelength for the excitation of MPM within the 1700 nm window.

High-performance pyrite nano-catalyst driven photothermal/chemodynamic synergistic therapy for Osteosarcoma Open

Meirong Li, Minghua Wang, Junfeng Huang, Shiqi Tang, Jingyu Yang , et al. · 2023

Osteosarcoma (OS) is an aggressive bone tumor with strong invasiveness, rapid metastasis and dreadful mortality. Chemotherapy is commonly used approach for OS treatment but was limited by the development of drug resistance and long-term ad…

Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II Open

Xiangwei Lin, Zhourui Xu, Jiangao Li, Hongji Shi, Zhenyu Fu , et al. · 2023

Visualization of photothermal therapy mediated by photothermal transduction agents (PTAs) is important to promote individual treatment of patients with low side effect. Photoacoustic detection has emerged as a promising noninvasive method …

Controlling the Energy Relaxation: Organic Doping in AIEgen Nanoparticles for Highly Enhanced Intravital Two‐Photon Imaging (Advanced Optical Materials 13/2023) Open

Miaozhuang Fan, Gang Feng, Lu Xia, Yibin Zhang, Maixian Liu , et al. · 2023

In article number 2300255, Yuanyuan Shen, Zhourui Xu, Gaixia Xu, and colleagues develop an organic doping method to boost the two-photon action cross-section of aggregation-induced emission luminogens (AIEgens) by providing a hydrophobic a…

Machine-learning screening of luminogens with aggregation-induced emission characteristics for fluorescence imaging Open

Yibin Zhang, Miaozhuang Fan, Zhourui Xu, Yihang Jiang, Huijun Ding , et al. · 2023

Multifunctional Mesoporous Silica-Coated Gold Nanorods Mediate Mild Photothermal Heating-Enhanced Gene/Immunotherapy for Colorectal Cancer Open

Meirong Li, Jingyu Yang, Xinhuang Yao, Xiang Li, Zhourui Xu , et al. · 2023

Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths in the world. It is urgent to search for safe and effective therapies to address the CRC crisis. The siRNA-based RNA in…

Redox-Directed Identification of Toxic Transformation Products During Ozonation of Aromatics Open

Jianjian Wei, Shuting Wang, Weixu Tang, Zhourui Xu, Dehua Ma , et al. · 2023

Formation and Toxicity Contribution of Chlorinated and Dechlorinated Halobenzoquinones from Dichlorophenols after Ozonation Open

Zhourui Xu, Jianjian Wei, Aroob Abid, Zirui Liu, Yasen Wu , et al. · 2023

Mesoporous silica-coated silver nanoparticles as ciprofloxacin/siRNA carriers for accelerated infected wound healing Open

Qiqi Liu, Ying Zhang, Jingkai Huang, Zhourui Xu, Xiang Li , et al. · 2022

Mesoporous silica-coated silver nanoparticles as ciprofloxacin and siRNA co-delivery multifunctional platform for accelerated infected wound healing Open

Qiqi Liu, Ying Zhang, Jingkai Huang, Zhourui Xu, Xiang Li , et al. · 2022

The colonization of bacterial pathogens is a major concern in wound infection and becoming a public health issue. Herein, a core-shell structured Ag@MSN (silver core embedded with mesoporous silica, AM)-based nanoplatform was elaborately f…

Recent advances in exosome-mediated nucleic acid delivery for cancer therapy Open

Ying Zhang, Qiqi Liu, Xinmeng Zhang, Haoqiang Huang, Shiqi Tang , et al. · 2022

Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 Open

Ying Zhang, Yujuan Chai, Zulu Hu, Zhourui Xu, Meirong Li , et al. · 2022

The outbreak of the coronavirus disease 2019 (COVID-19) has resulted in enormous losses worldwide. Through effective control measures and vaccination, prevention and curbing have proven significantly effective; however, the disease has sti…

CuS@BSA-NB2 Nanoparticles for HER2-Targeted Photothermal Therapy Open

Ming Ying, Qin Li, Jingbo Wu, Yihang Jiang, Zhourui Xu , et al. · 2022

Breast cancer is characterized by the uncontrolled proliferation of breast epithelial cells under the action of a variety of carcinogens. Although HER2-inhibitors were currently applied for HER2-positive breast cancer patients, they didn’t…

In-Situ Construction of Fluorescent Probes for Lysosomes Imaging and Lysosomal Ph Ratiometric Detection Based on Bioorthogonal Fluorescence Open

Gang Feng, Zhengzheng Li, Peng Zhai, Mingsheng Ying, Zhourui Xu , et al. · 2022

Highly biocompatible chlorin e6-poly(dopamine) core–shell nanoparticles for enhanced cancer phototherapy Open

Shilin Chen, Yihang Jiang, Miaozhaung Fan, Xinmeng Zhang, Ying Zhang , et al. · 2022

Biocompatible photothermal/photodynamic dual-mode therapeutic nanoparticles (CBP NPs) were successfully designed and constructed based on the Food and Drug Administration (FDA)-approved ingredients.

A Mitochondrion-Targeting Two-Photon Photosensitizer with Aggregation-Induced Emission Characteristics for Hypoxia-Tolerant Photodynamic Therapy Open

Yihang Jiang, Wei Zhu, Zhourui Xu, Zhijun Zhang, Shuo Tang , et al. · 2022

Carbon Dioxide-Derived Biodegradable and Cationic Polycarbonates as a New siRNA Carrier for Gene Therapy in Pancreatic Cancer Open

Xinmeng Zhang, Zheng‐Ian Lin, Jingyu Yang, Guanlin Liu, Zulu Hu , et al. · 2021

Pancreatic cancer is an aggressive malignancy associated with poor prognosis and a high tendency in developing infiltration and metastasis. K-ras mutation is a major genetic disorder in pancreatic cancer patient. RNAi-based therapies can b…

Metal organic framework-coated gold nanorod as an on-demand drug delivery platform for chemo-photothermal cancer therapy Open

Junfeng Huang, Zhourui Xu, Yihang Jiang, Wing‐Cheung Law, Biqin Dong , et al. · 2021

Chemo-photothermal therapy based on nanoparticles has emerged as a promising strategy for cancer treatment. However, its therapeutic efficacy and application potential are largely subjected to the uncontrollability and biotoxicity of funct…

NIR-II-activated biocompatible hollow nanocarbons for cancer photothermal therapy Open

Zhourui Xu, Yinling Zhang, Weixiao Zhou, Lijian Wang, Gaixia Xu , et al. · 2021

Photothermal therapy has attracted extensive attentions in cancer treatment due to its precise spatial-temporal controllability, minimal invasiveness, and negligible side effects. However, two major deficiencies, unsatisfactory heat conver…

Seawater Desalination by Interfacial Solar Vapor Generation Method Using Plasmonic Heating Nanocomposites Open

Zhourui Xu, Nanxi Rao, Chak Yin Tang, Wing‐Cheung Law · 2020

With the ever-growing demand in fresh water supply, great efforts have been devoted to developing sustainable systems which could generate fresh water continuously. Solar vapor generation is one of the promising strategies which comprise a…

Recent advances in solar-driven evaporation systems Open

Zhourui Xu, Zida Li, Yihang Jiang, Gaixia Xu, Mingwei Zhu , et al. · 2020

Solar-driven evaporation as a promising and sustainable approach to convert solar energy into freshwater resource is attracting huge interest in the research community. This review aims to summarize the recent advances in system designs of…

Aqueous Phase Synthesis of Cu2–xS Nanostructures and Their Photothermal Generation Study Open

Zhourui Xu, Nanxi Rao, Chak Yin Tang, Ching‐Hsiang Cheng, Wing‐Cheung Law · 2019

Size- and shape-dependent features of plasmonic nanocrystals govern the development of their applications. In the past decades, gold nanostructures, such as gold nanorods and nanoshells, have been well studied and applied for sensing, bioi…

Manganese-doped near-infrared emitting nanocrystals for in vivo biomedical imaging Open

Wing‐Cheung Law, Zhourui Xu, Ken‐Tye Yong, Xin Liu, Mark T. Swihart , et al. · 2016

Nanoprobes with multiple imaging modality have attracted a great deal of attention due to the capability of offering complementary information from each individual component. This work presents a hybrid approach to synthesize manganese dop…

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