Zhu He-shui
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View article: Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy Open
Alphaherpesvirus infection results in severe health consequences in a wide range of hosts. USPs are the largest subfamily of deubiquitinating enzymes that play critical roles in immunity and other cellular functions. To investigate the rol…
View article: Characterization and anti-inflammation role of swine IFITM3 gene
Characterization and anti-inflammation role of swine IFITM3 gene Open
IFITM3 is involved in cell adhesion, apoptosis, immune, and antivirus activity. Furthermore, IFITM3 gene has been considered as a preferential marker for inflammatory diseases, and positive correlation to pathological grades. Therefore, we…
View article: Swine IRF3/IRF7 attenuates inflammatory responses through TLR4 signaling pathway
Swine IRF3/IRF7 attenuates inflammatory responses through TLR4 signaling pathway Open
To explore the role of IRF3/IRF7 during inflammatory responses, we investigated the effects of swine IRF3/IRF7 on TLR4 signaling pathway and inflammatory factors expression in porcine kidney epithelial PK15 cell lines. We successfully cons…