Zhuokai Li
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View article: Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia
Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia Open
Comparing false-negative and false-positive rates for stability across rules allows selection of the most appropriate rule for clinical practice or research. When considering less desirable treatments, a rule with a lower false-negative ra…
View article: Insufficient stem antetorsion and lower cup abduction is a combined risk factor for posterior hip dislocation in patients undergoing THA for femoral neck fractures: a retrospective analysis
Insufficient stem antetorsion and lower cup abduction is a combined risk factor for posterior hip dislocation in patients undergoing THA for femoral neck fractures: a retrospective analysis Open
Background The role of acetabular and femoral component positions with respect to the risk of post-operative instability and dislocation remains debated. In this study, we aimed to identify potential risk factors for early dislocation foll…
View article: Eight-Year Outcomes of Bilateral Lateral Rectus Recessions versus Unilateral Recession-Resection in Childhood Basic-Type Intermittent Exotropia
Eight-Year Outcomes of Bilateral Lateral Rectus Recessions versus Unilateral Recession-Resection in Childhood Basic-Type Intermittent Exotropia Open
View article: A Pilot Randomized Clinical Trial of Base-in Relieving Prism Spectacle Treatment of Intermittent Exotropia
A Pilot Randomized Clinical Trial of Base-in Relieving Prism Spectacle Treatment of Intermittent Exotropia Open
SIGNIFICANCE This pilot randomized trial, the first to evaluate a specific base-in relieving prism treatment strategy for childhood intermittent exotropia, did not support proceeding to a full-scale clinical trial. Defining and measuring p…
View article: Complications Occurring Through 5 Years Following Primary Intraocular Lens Implantation for Pediatric Cataract
Complications Occurring Through 5 Years Following Primary Intraocular Lens Implantation for Pediatric Cataract Open
Importance Lensectomy with primary intraocular lens (IOL) implantation is often used in the management of nontraumatic pediatric cataract, but long-term data evaluating the association of age and IOL location with the incidence of complica…
View article: Improved control of intermittent exotropia with part-time patching
Improved control of intermittent exotropia with part-time patching Open
View article: EMP1 as a Potential Biomarker in Liver Fibrosis: A Bioinformatics Analysis
EMP1 as a Potential Biomarker in Liver Fibrosis: A Bioinformatics Analysis Open
Liver fibrosis is a wound-healing response to chronic injury, which may result in cirrhosis and liver failure. Studies have been carried on the mechanisms and pathogenesis of liver fibrosis. However, the potential cell-specific expressed m…
View article: Incidence of Glaucoma-Related Adverse Events in the First 5 Years After Pediatric Lensectomy
Incidence of Glaucoma-Related Adverse Events in the First 5 Years After Pediatric Lensectomy Open
Importance Glaucoma can develop following cataract removal in children. Objective To assess the cumulative incidence of glaucoma-related adverse events (defined as glaucoma or glaucoma suspect) and factors associated with risk of these adv…
View article: Ocular and developmental outcomes of a dosing study of bevacizumab for retinopathy of prematurity
Ocular and developmental outcomes of a dosing study of bevacizumab for retinopathy of prematurity Open
View article: Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma Open
Our study suggests that PKMYT1 functions as an oncogene and may be a new target for HCC treatment.
View article: Relationships among Clinical Factors and Patient-reported Outcome Measures in Adults with Convergence Insufficiency
Relationships among Clinical Factors and Patient-reported Outcome Measures in Adults with Convergence Insufficiency Open
SIGNIFICANCE When exploring relationships among clinical measures and patient-reported outcome measures in adults with convergence insufficiency, worse symptoms (Convergence Insufficiency Symptom Survey [CISS] score) seemed to be correlate…
View article: Low- and Very Low-Dose Bevacizumab for Retinopathy of Prematurity
Low- and Very Low-Dose Bevacizumab for Retinopathy of Prematurity Open
View article: Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke
Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke Open
ClinicalTrials.gov Identifier: NCT02415400.
View article: Parent-provided photographs as an outcome measure for childhood chalazia
Parent-provided photographs as an outcome measure for childhood chalazia Open
View article: Plasma Levels of Bevacizumab and Vascular Endothelial Growth Factor After Low-Dose Bevacizumab Treatment for Retinopathy of Prematurity in Infants
Plasma Levels of Bevacizumab and Vascular Endothelial Growth Factor After Low-Dose Bevacizumab Treatment for Retinopathy of Prematurity in Infants Open
Results of this phase 1 dose de-escalation case series study revealed that bevacizumab doses as low as 0.002 mg were associated with reduced plasma VEGF levels for most infants at 2 and 4 weeks after intravitreal administration; however, n…
View article: Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2
Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2 Open
Urolithin A (UA) is an intestinal microbial metabolite derived from ellagitannins and a promising agent for treating osteoarthritis. However, its effects on osteoporosis are unclear. This study explored the effects of urolithin A (UA) on r…
View article: Visual Acuity and Ophthalmic Outcomes 5 Years After Cataract Surgery Among Children Younger Than 13 Years
Visual Acuity and Ophthalmic Outcomes 5 Years After Cataract Surgery Among Children Younger Than 13 Years Open
In this cohort study, development of glaucoma or glaucoma suspect was common in children 5 years after lensectomy. Myopic shift was modest during the 5 years after placement of an intraocular lens, which should be factored into implant pow…
View article: Identification of Therapeutic Targets and Prognostic Biomarkers among Genes from the Mediator Complex Family in the Hepatocellular Carcinoma Tumour-Immune Microenvironment
Identification of Therapeutic Targets and Prognostic Biomarkers among Genes from the Mediator Complex Family in the Hepatocellular Carcinoma Tumour-Immune Microenvironment Open
Background. Hepatocellular carcinoma (HCC) is predominant among all types of primary liver cancers characterised by high morbidity and mortality. Genes in the mediator complex (MED) family are engaged in the tumour-immune microenvironment …
View article: miR-221-3p regulates hepatocellular carcinoma cell proliferation, migration and invasion via targeting LIFR
miR-221-3p regulates hepatocellular carcinoma cell proliferation, migration and invasion via targeting LIFR Open
View article: Choice of Dose Level for a Randomized Clinical Trial of Low-Dose Bevacizumab vs Laser for Type 1 Retinopathy of Prematurity
Choice of Dose Level for a Randomized Clinical Trial of Low-Dose Bevacizumab vs Laser for Type 1 Retinopathy of Prematurity Open
This study determines which of 8 doses of bevacizumab are effective in treating severe retinopathy of prematurity to carry forward to a large-scale randomized clinical trial.
View article: Baicalein ameliorates osteoporosis via AKT/FOXO1 signaling
Baicalein ameliorates osteoporosis via AKT/FOXO1 signaling Open
In this study, we used bioinformatics and an in vitro cellular model of glucocorticoid-induced osteoporosis to investigate mechanisms underlying the beneficial effects of baicalein (BN) against osteoporosis. STITCH database analysis…
View article: Rasch calibrated Symptom Questionnaire for Childhood Intermittent Exotropia
Rasch calibrated Symptom Questionnaire for Childhood Intermittent Exotropia Open
View article: Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p
Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p Open
Objectives The aim of this study was to investigate the effects of exosomes isolated from human bone marrow mesenchymal stem cells (BMSCs) on osteoarthritis (OA) and a competitive endogenous RNA (ceRNA) network. Methods Exosomes were isola…
View article: Variation in Antithrombotic Therapy and Clinical Outcomes in Patients With Preexisting Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement
Variation in Antithrombotic Therapy and Clinical Outcomes in Patients With Preexisting Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement Open
Background: Optimal antithrombotic management of patients with preexisting atrial fibrillation undergoing transcatheter aortic valve replacement is challenging given the need to balance the risk of bleeding and thromboembolism. We aimed to…
View article: MiR-20b-5p promotes hepatocellular carcinoma cell proliferation, migration and invasion by down-regulating CPEB3
MiR-20b-5p promotes hepatocellular carcinoma cell proliferation, migration and invasion by down-regulating CPEB3 Open
The present study proved that miR-20b-5p promotes HCC cell proliferation, migration and invasion by inhibiting CPEB3 expression, which may provide a theoretical basis for the prognosis and treatment of HCC patients.
View article: Practical Application of Patient-Reported Health Status Measures for Transcatheter Valve Therapies
Practical Application of Patient-Reported Health Status Measures for Transcatheter Valve Therapies Open
Background: Health status assessment is essential for documenting the benefit of transcatheter aortic valve replacement (TAVR) or transcatheter mitral valve repair on patients’ symptoms, function, and quality of life. Health status can als…
View article: Long non‑coding RNA small nucleolar RNA host gene 1 knockdown suppresses the proliferation, migration and invasion of osteosarcoma cells by regulating microRNA‑424‑5p/FGF2 <i>in vitro</i>
Long non‑coding RNA small nucleolar RNA host gene 1 knockdown suppresses the proliferation, migration and invasion of osteosarcoma cells by regulating microRNA‑424‑5p/FGF2 <i>in vitro</i> Open
The aim of the present study was to clarify the effect of long non-coding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) on the proliferation, migration and invasion of osteosarcoma (OS) cells and to explore the potential underlying …
View article: Patient-Perceived Versus Actual Risk of Cardiovascular Disease and Associated Willingness to Consider and Use Prevention Therapy
Patient-Perceived Versus Actual Risk of Cardiovascular Disease and Associated Willingness to Consider and Use Prevention Therapy Open
Background: Cardiovascular prevention guidelines use estimated 10-year atherosclerotic cardiovascular disease (CVD) risk based on the pooled cohort equations to guide treatment decisions and engage patients in shared decision-making. We so…
View article: [Retracted] Trophinin Is an Important Biomarker and Prognostic Factor in Osteosarcoma: Data Mining from Oncomine and the Cancer Genome Atlas Databases
[Retracted] Trophinin Is an Important Biomarker and Prognostic Factor in Osteosarcoma: Data Mining from Oncomine and the Cancer Genome Atlas Databases Open
Osteosarcoma (OS) is a type of bone malignancy with a high rate of treatment failure. To date, few evident biomarkers for the prognostic significance of OS have been established. Oncomine was used to integrate RNA and DNA‐seq data from the…
View article: Beliefs, risk perceptions, and lipid management among patients with and without diabetes: Results from the PALM registry
Beliefs, risk perceptions, and lipid management among patients with and without diabetes: Results from the PALM registry Open