Zongzhi Yin
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View article: Efficacy and outcomes of total tubeless single-port thoracoscopic wedge resection for peripheral pulmonary nodules
Efficacy and outcomes of total tubeless single-port thoracoscopic wedge resection for peripheral pulmonary nodules Open
TT single-port thoracoscopic wedge resection is a safe and effective approach for treating peripheral pulmonary nodules.
View article: SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse Open
Our results revealed that SGK1 could potentially slow down the progression of POP under OS by interacting with GSK-3β to promote the GSK-3β (Ser9)/Fyn/NRF2 pathway, which provides a potential therapeutic approach for treating POP.
View article: FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity Open
Obese pregnant women in late pregnancy are more susceptible to uterine smooth muscle dysfunction, but the underlying mechanisms remain elusive. Here, elevated levels of fatty acid binding protein 4 (FABP4) in the myometrium of obese pregna…
View article: Inflammation-induced PFKFB3-mediated glycolysis promoting myometrium contraction through the PI3K-Akt-mTOR pathway in preterm birth mice
Inflammation-induced PFKFB3-mediated glycolysis promoting myometrium contraction through the PI3K-Akt-mTOR pathway in preterm birth mice Open
Expression of PFKFB3, a key enzyme in glycolysis, was significantly upregulated both in the mUSMCs and myometrium of mice during late pregnancy after lipopolysaccharide stimulation. Activation of the PI3K-Akt-mTOR pathway enhanced PFKFB3 e…
View article: The relationships of metals exposure and disturbance of the vaginal microbiota with the risk of PROM: Results from a birth cohort study
The relationships of metals exposure and disturbance of the vaginal microbiota with the risk of PROM: Results from a birth cohort study Open
The vaginal microbiota is proposed to be associated with reproductive health. Exposure to metals during pregnancy is a risk factor for premature rupture of membranes (PROM). PROM can lead to serious maternal complications, thus, identifyin…
View article: Vaginal microbiota in term pregnant women with differences in cervical ripeness revealed by 2bRAD-M
Vaginal microbiota in term pregnant women with differences in cervical ripeness revealed by 2bRAD-M Open
For the first time, vaginal microbiota was sequenced using 2bRAD-M. With a relatively simple structure, a more stable vaginal microbiota is associated with higher cervical ripeness, and certain microorganisms, such as Sphingomonas, may pla…
View article: Amnioinfusion compared with expectant management in oligohydramnios with intact amnions in the second and early third trimesters
Amnioinfusion compared with expectant management in oligohydramnios with intact amnions in the second and early third trimesters Open
Introduction Treatment of oligohydramnios in the mid‐trimester is challenging, because of the high incidence of adverse perinatal outcomes mainly due to bronchopulmonary dysplasia. Antenatal amnioinfusion has been proposed as a possible tr…
View article: MTCH2 in Metabolic Diseases, Neurodegenerative Diseases, Cancers, Embryonic Development and Reproduction
MTCH2 in Metabolic Diseases, Neurodegenerative Diseases, Cancers, Embryonic Development and Reproduction Open
Mitochondrial carrier homolog 2 (MTCH2) is a member of the solute carrier 25 family, located on the outer mitochondrial membrane. MTCH2 was first identified in 2000. The development in MTCH2 research is rapidly increasing. The most well-kn…
View article: Light pollution during pregnancy influences the growth of offspring in rats
Light pollution during pregnancy influences the growth of offspring in rats Open
Excessive light exposure during pregnancy results in elevated cortisol and reduced melatonin exposure to fetuses in uterus, potentially contributing to an accelerated early growth of offspring in rats.
View article: Facile Semiconductor p–n Homojunction Nanowires with Strategic p-Type Doping Engineering Combined with Surface Reconstruction for Biosensing Applications
Facile Semiconductor p–n Homojunction Nanowires with Strategic p-Type Doping Engineering Combined with Surface Reconstruction for Biosensing Applications Open
View article: Gestational diabetes mellitus: The optimal time of delivery
Gestational diabetes mellitus: The optimal time of delivery Open
Gestational diabetes mellitus (GDM) is a common pregnancy complication strongly associated with poor maternal-fetal outcomes. Its incidence and prevalence have been increasing in recent years. Women with GDM typically give birth through ei…
View article: RETRACTED: High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy
RETRACTED: High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy Open
Background The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. GDM patients have a significantly higher rate of cesarean section and postpartum hemorrhage, suggesting changes in uterine contractility. TWIK-1-relat…
View article: Uteroplacental–Cerebral Ratio: A Doppler Parameter for Prognostic Prediction of Late-Onset Fetal Growth Restriction: Single Center Prospective Cohort Study
Uteroplacental–Cerebral Ratio: A Doppler Parameter for Prognostic Prediction of Late-Onset Fetal Growth Restriction: Single Center Prospective Cohort Study Open
Purpose: This study aimed to elucidate the accuracy of Doppler parameters in predicting the prognosis of late-onset fetal growth restriction (FGR). Methods: This was a prospective study of 114 pregnancies. Doppler parameters, including the…
View article: Comparative single-center study between modified laparoscopic radical hysterectomy and open radical hysterectomy for early-stage cervical cancer
Comparative single-center study between modified laparoscopic radical hysterectomy and open radical hysterectomy for early-stage cervical cancer Open
View article: Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study
Optimal delivery time for patients with diet-controlled gestational diabetes mellitus: a single-center real-world study Open
Background To determine the optimal delivery time for women with diet-controlled gestational diabetes mellitus by comparing differences in adverse maternal–fetal outcome and cesarean section rates. Methods This real-world retrospective stu…
View article: Preserved Oxytocin-Induced Myometrium Contraction and Sensitivity to Progesterone Inhibition Following Rat Uterus Thermal Insult. Impact on Fertility
Preserved Oxytocin-Induced Myometrium Contraction and Sensitivity to Progesterone Inhibition Following Rat Uterus Thermal Insult. Impact on Fertility Open
View article: Maternal tobacco exposure and health-related quality of life during pregnancy: a national-based study of pregnant women in China
Maternal tobacco exposure and health-related quality of life during pregnancy: a national-based study of pregnant women in China Open
View article: Application of Modified Laparoscopic Radical Hysterectomy in The Treatment of Early Cervical Cancer
Application of Modified Laparoscopic Radical Hysterectomy in The Treatment of Early Cervical Cancer Open
Background: To investigate the safety and efficacy of modified laparoscopic radical hysterectomy (MLRH) in the treatment of early stage cervical cancer by comparing relevant indices of different surgical procedures in patients with early s…
View article: Cerclage placement in twin pregnancies with cervical dilation: a systematic review and meta-analysis
Cerclage placement in twin pregnancies with cervical dilation: a systematic review and meta-analysis Open
Existing guidelines and studies on the benefits of cerclage in twin pregnancies with a dilated cervix have low reliability and inconsistent conclusions. New randomized control trials and cohort studies focusing on twin pregnancies with cer…
View article: Psychobehavioral Responses, Post‐Traumatic Stress and Depression in Pregnancy During the Early Phase of COVID‐19 Outbreak
Psychobehavioral Responses, Post‐Traumatic Stress and Depression in Pregnancy During the Early Phase of COVID‐19 Outbreak Open
High prevalence of PND and PTSD and high levels of anxiety suggest profound impacts of the present outbreak on mental health. This calls for special attention and support for vulnerable populations. Mental health care should become part of…
View article: Prolonged stretching in the late-late pregnant rat uterus inhibits contractions through potassium channel TREK-1
Prolonged stretching in the late-late pregnant rat uterus inhibits contractions through potassium channel TREK-1 Open
Background Prolonged stretching can inhibit myometrial contractions in the nonpregnant and the mid- and late-term pregnant uteri of rats and humans through potassium channel TREK-1. What happens in the pregnant uterus close to parturition …
View article: Maternal Tobacco Exposure and Health-Related Quality of Life during Pregnancy: A National-based Study of 15682 Pregnant Women in China
Maternal Tobacco Exposure and Health-Related Quality of Life during Pregnancy: A National-based Study of 15682 Pregnant Women in China Open
Background With the increase of the number of smokers, tobacco exposure among pregnant women is becoming more and more common. Though that pregnant women exposed to first-hand smoke and second-hand smoke are susceptible to physiological an…
View article: Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells
Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells Open
Introduction: Interleukin (IL)-1β, as a key biomarker and mediator of vascular calcification in patients with end-stage renal disease (ESRD), may be involved in the process of premature senescence of vascular smooth muscle ce…
View article: Real-time Tumor Motion Monitoring and PTV Margin Determination in Lung SBRT Treatment
Real-time Tumor Motion Monitoring and PTV Margin Determination in Lung SBRT Treatment Open
View article: A retrospective cohort study of risk factors and pregnancy outcomes in 14,014 Chinese pregnant women
A retrospective cohort study of risk factors and pregnancy outcomes in 14,014 Chinese pregnant women Open
This study aims to investigate major complications or symptoms of pregnant women, causes of maternal near-miss, and issues that are relevant to severe maternal disease.A retrospective analysis was performed in the "maternal individual inve…
View article: Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus
Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus Open
Uterus from late-pregnant rats (gestational day 19) was isolated, and uterine strips were prepared for isometric contraction measurement. Oxytocin-induced contraction was compared in uterine strips pretreated with different concentration o…
View article: Role of human cytomegalovirus in the proliferation and invasion of extravillous cytotrophoblasts isolated from early placentae.
Role of human cytomegalovirus in the proliferation and invasion of extravillous cytotrophoblasts isolated from early placentae. Open
HCMV may act on multiple steps of the TGF-β/Smad signaling pathway to impede EVT proliferation and invasion.