Hua Zhang
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View article: Characterization of microbiota dysbiosis in papillary thyroid carcinoma and benign thyroid nodules: low abundance of intestinal butyrate-producing bacteria
Characterization of microbiota dysbiosis in papillary thyroid carcinoma and benign thyroid nodules: low abundance of intestinal butyrate-producing bacteria Open
View article: Maxent model-based prediction of the potential distribution of Fritillaria taipaiensis P. Y. Li
Maxent model-based prediction of the potential distribution of Fritillaria taipaiensis P. Y. Li Open
View article: Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic review and meta-analysis
Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic review and meta-analysis Open
Introduction The risk of kidney fibrosis is significantly elevated in individuals with diabetes, chronic nephritis, trauma, and other underlying conditions. Concurrently, human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs…
View article: Alterations in intestinal butyrate-producing Streptococcus and Veillonella species are associated with the severity of hepatitis E
Alterations in intestinal butyrate-producing Streptococcus and Veillonella species are associated with the severity of hepatitis E Open
View article: Synergy of diazotrophs with native soil microbes improves poplar traits
Synergy of diazotrophs with native soil microbes improves poplar traits Open
View article: Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity exacerbating skin damage in trichloroethylene hypersensitivity syndrome
Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity exacerbating skin damage in trichloroethylene hypersensitivity syndrome Open
Trichloroethylene (TCE)-induced hypersensitivity syndrome (THS) has been a concern for many researchers in the field of environmental and occupational health. Currently, there is no specific treatment for THS, leaving patients to contend w…
View article: Microbiota-gut-liver-brain axis and hepatic encephalopathy
Microbiota-gut-liver-brain axis and hepatic encephalopathy Open
Hepatic encephalopathy (HE) is a clinical manifestation of neurological and psychiatric abnormalities that are caused by complications of liver dysfunction including hyperammonemia, hyperuricemia, and portal hypertension. Accumulating evid…
View article: The cGAS-STING Pathway in Bacterial Infection and Bacterial Immunity
The cGAS-STING Pathway in Bacterial Infection and Bacterial Immunity Open
Cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) (cGAMP) synthase (cGAS), along with the adaptor stimulator of interferon genes (STING), are crucial components of the innate immune system, and their study has become a res…
View article: Multiple Intestinal Bacteria Associated with the Better Protective Effect of <i>Bifidobacterium pseudocatenulatum</i> LI09 against Rat Liver Injury
Multiple Intestinal Bacteria Associated with the Better Protective Effect of <i>Bifidobacterium pseudocatenulatum</i> LI09 against Rat Liver Injury Open
Bifidobacterium pseudocatenulatum LI09 could protect rats from D‐galactosamine‐ (D‐GalN‐) induced liver injury. However, individual difference in the protective effects of LI09 on the liver injury remains poorly understood. The present stu…
View article: Lactitol Supplementation Modulates Intestinal Microbiome in Liver Cirrhotic Patients
Lactitol Supplementation Modulates Intestinal Microbiome in Liver Cirrhotic Patients Open
Background: Cirrhosis is a common chronic liver disease characterized by irreversible diffuse liver damage. Intestinal microbiome dysbiosis and metabolite dysfunction contribute to the development of cirrhosis. Lactitol (4-β-D-galactopyran…
View article: Antibacterial Activity and Membrane-Targeting Mechanism of Aloe-Emodin Against Staphylococcus epidermidis
Antibacterial Activity and Membrane-Targeting Mechanism of Aloe-Emodin Against Staphylococcus epidermidis Open
The emergence of multidrug-resistant Staphylococcus epidermidis ( S. epidermidis) dwarfs the current antibiotic development and calls for the discovery of new antibacterial agents. Aloe-emodin is a plant-derived compound that holds promise…
View article: Oral Microbiome Characteristics in Patients With Autoimmune Hepatitis
Oral Microbiome Characteristics in Patients With Autoimmune Hepatitis Open
Autoimmune hepatitis (AIH) is a common cause of liver cirrhosis. To identify the characteristics of the oral microbiome in patients with AIH, we collected 204 saliva samples including 68 AIH patients and 136 healthy controls and performed …
View article: Microbiome–miRNA interactions in the progress from undifferentiated arthritis to rheumatoid arthritis: evidence, hypotheses, and opportunities
Microbiome–miRNA interactions in the progress from undifferentiated arthritis to rheumatoid arthritis: evidence, hypotheses, and opportunities Open
View article: Gut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical features
Gut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical features Open
The relationship between gut microbes and COVID-19 or H1N1 infections is not fully understood. Here, we compared the gut mycobiota of 67 COVID-19 patients, 35 H1N1-infected patients and 48 healthy controls (HCs) using internal transcribed …
View article: Six-month follow-up of gut microbiota richness in patients with COVID-19
Six-month follow-up of gut microbiota richness in patients with COVID-19 Open
We read with great interest the recent article published in Gut in which Yeoh et al demonstrated that gut microbiota composition of recovered patients with COVID-19 remained significantly distinct from uninfected controls.1 Persisting symp…
View article: Alterations in the human oral and gut microbiomes and lipidomics in COVID-19
Alterations in the human oral and gut microbiomes and lipidomics in COVID-19 Open
Objective To characterise the oral microbiome, gut microbiome and serum lipid profiles in patients with active COVID-19 and recovered patients; evaluate the potential of the microbiome as a non-invasive biomarker for COVID-19; and explore …
View article: The faecal metabolome in COVID-19 patients is altered and associated with clinical features and gut microbes
The faecal metabolome in COVID-19 patients is altered and associated with clinical features and gut microbes Open
View article: Vital Members in the More Dysbiotic Oropharyngeal Microbiotas in H7N9-Infected Patients
Vital Members in the More Dysbiotic Oropharyngeal Microbiotas in H7N9-Infected Patients Open
The dysbiosis of oropharyngeal (OP) microbiota is associated with multiple diseases, including H7N9 infection. Different OP microbial colonization states may reflect different severities or stages of disease and affect the effectiveness of…
View article: Plasma Level of ADAMTS13 or IL-12 as an Indicator of HBeAg Seroconversion in Chronic Hepatitis B Patients Undergoing m-ETV Treatment
Plasma Level of ADAMTS13 or IL-12 as an Indicator of HBeAg Seroconversion in Chronic Hepatitis B Patients Undergoing m-ETV Treatment Open
The ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin motif repeats 13) is a key factor involved in coagulation process and plays a vital role in the progression and prognosis of chronic hepatitis B (CHB) patients with an…
View article: Matrine-chitosan hydrogels for treating subclinical bovine mastitis by intramammary infusion—effect on milk microbiome and metabolites
Matrine-chitosan hydrogels for treating subclinical bovine mastitis by intramammary infusion—effect on milk microbiome and metabolites Open
BackgroundThe metabolic processes of cows undergo significant changes during subclinical mastitis, but their molecular mechanisms have not been clearly elucidated. This study investigated the changes in milk metabolites after intramammary …
View article: Impact of mutational variant allele frequency on prognosis in myelodysplastic syndromes.
Impact of mutational variant allele frequency on prognosis in myelodysplastic syndromes. Open
The clinical relevance of variant allele frequency (VAF) of recurrent mutations in myelodysplastic syndromes (MDS) has been increasingly reported. However, the prognostic value of mutational VAF across the genetic spectrum of MDS has not b…
View article: Fecal Microbiome Data Distinguish Liver Recipients With Normal and Abnormal Liver Function From Healthy Controls
Fecal Microbiome Data Distinguish Liver Recipients With Normal and Abnormal Liver Function From Healthy Controls Open
Emerging evidence suggests that altered intestinal microbiota plays an important role in the pathogenesis of many liver diseases, mainly by promoting inflammation via the "intestinal microbiota-immunity-liver" axis. We aimed to investigate…
View article: Bank performance in China: A Perspective from Bank efficiency, risk-taking and market competition
Bank performance in China: A Perspective from Bank efficiency, risk-taking and market competition Open
View article: Gut Microbiota Changes in Patients with Bipolar Depression
Gut Microbiota Changes in Patients with Bipolar Depression Open
This study aims to characterize the gut microbiota in depressed patients with bipolar disorder (BD) compared with healthy controls (HCs), to examine the effects of quetiapine treatment on the microbiota, and to explore the potential of mic…
View article: Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma
Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma Open
Objective To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC. Design We collected 486 faecal samples from East China, Central China and…
View article: Isocitrate dehydrogenase 2 mutations correlate with leukemic transformation and are predicted by 2-hydroxyglutarate in myelodysplastic syndromes
Isocitrate dehydrogenase 2 mutations correlate with leukemic transformation and are predicted by 2-hydroxyglutarate in myelodysplastic syndromes Open
View article: Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China
Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China Open
Pancreatic carcinoma (PC) is a lethal cancer. Gut microbiota is associated with some risk factors of PC, e.g. obesity and types II diabetes. However, the specific gut microbial profile in clinical PC in China has never been reported. This …
View article: Interest Rate Liberalization and Bank Performance in China
Interest Rate Liberalization and Bank Performance in China Open
View article: Deep sequencing reveals microbiota dysbiosis of tongue coat in patients with liver carcinoma
Deep sequencing reveals microbiota dysbiosis of tongue coat in patients with liver carcinoma Open
Liver carcinoma (LC) is a common malignancy worldwide, associated with high morbidity and mortality. Characterizing microbiome profiles of tongue coat may provide useful insights and potential diagnostic marker for LC patients. Herein, we …
View article: The Effect of Probiotic Treatment on Patients Infected with the H7N9 Influenza Virus
The Effect of Probiotic Treatment on Patients Infected with the H7N9 Influenza Virus Open
H7N9 infection might decrease intestinal microbial diversity and species richness in humans. C. butyricum failed to reduce/ameliorate secondary infection in H7N9-infected patients. B. subtilis and E. faecium may also play a role in reducin…