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View article: In Situ Growth of Cross-Linked Ti2Nb10O29 Nanoparticles on Inner/Outer Surfaces of Carbon Microtubes for High-Efficiency Lithium Storage
In Situ Growth of Cross-Linked Ti2Nb10O29 Nanoparticles on Inner/Outer Surfaces of Carbon Microtubes for High-Efficiency Lithium Storage Open
Improving electronic and ionic transport and the structural stability of electrode materials is essential for the development of advanced lithium-ion batteries. Despite its great potential as a high-power anode, Ti2Nb10O29 (TNO) still unde…
View article: Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2026
Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2026 Open
The National Genomics Data Center (NGDC), as part of the China National Center for Bioinformation (CNCB), provides a suite of database resources for worldwide researchers. As multi-omics big data and artificial intelligence reshape the par…
View article: TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution
TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution Open
Transposable elements (TEs) are repetitive DNA sequences typically silenced in normal tissues. Their dysregulation in cancer can significantly impact oncogene activation and tumorigenesis. However, due to their repetitive nature, TEs are o…
View article: Unveiling the heterosis pattern of modern maize breeding in Southwest China through population structure and genetic diversity analysis
Unveiling the heterosis pattern of modern maize breeding in Southwest China through population structure and genetic diversity analysis Open
Maize (Zea mays L.) is an important food crop throughout the world and is also one of the earliest crops to use heterosis. In this study, we evaluated the genetic diversity, population structure, and selective sweep of 100 elite inbred mai…
View article: Calibration-free optical waveguide bending sensor for soft robots
Calibration-free optical waveguide bending sensor for soft robots Open
Soft robots have become increasingly popular due to their compliance, deformability, and adaptability. Soft sensors, particularly bending sensors, play a crucial role in providing essential posture and position information for these robots…
View article: A feature-preserving parallel particle generation method for complex geometries
A feature-preserving parallel particle generation method for complex geometries Open
In this paper, a Feature-preserving Particle Generation (FPPG) method for arbitrary complex geometry is proposed. Instead of basing on implicit geometries, such as level-set, FPPG employs an explicit geometric representation for the parall…
View article: Research Progress of LEF1 Gene in Malignant Tumors
Research Progress of LEF1 Gene in Malignant Tumors Open
Currently, one of the most dynamic and rapidly advancing areas in biomedical research is the study of cell signaling systems. In particular, researchers have directed significant attention toward the Wnt signaling pathway, which has emerge…
View article: Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2025
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2025 Open
The National Genomics Data Center (NGDC), which is a part of the China National Center for Bioinformation (CNCB), offers a comprehensive suite of database resources to support the global scientific community. Amidst the unprecedented accum…
View article: CancerSCEM 2.0: an updated data resource of single-cell expression map across various human cancers
CancerSCEM 2.0: an updated data resource of single-cell expression map across various human cancers Open
The field of single-cell RNA sequencing (scRNA-seq) has advanced rapidly in the past decade, generating significant amounts of valuable data for researchers to study complex tumor profiles. This data is crucial for gaining innovative insig…
View article: Recent advances in flexible bending sensors and their applications
Recent advances in flexible bending sensors and their applications Open
Flexible bending sensors have emerged as a technology with significant potential for a wide range of applications, including human-machine interaction, healthcare monitoring, and soft robotics. This paper provides a comprehensive review of…
View article: SPX family response to low phosphorus stress and the involvement of ZmSPX1 in phosphorus homeostasis in maize
SPX family response to low phosphorus stress and the involvement of ZmSPX1 in phosphorus homeostasis in maize Open
Phosphorus (P) is a crucial macronutrient for plant growth and development, and low-Pi stress poses a significant limitation to maize production. While the role of the SPX domain in encoding proteins involved in phosphate (Pi) homeostasis …
View article: Sertindole inhibits autophagic flux and glioma progression
Sertindole inhibits autophagic flux and glioma progression Open
Gliomas, the most lethal brain tumors, often exhibit resistance to conventional chemotherapy and/or radiotherapy. This study reveals that sertindole, a potent dopamine D2 receptor antagonist primarily designed as an antipsychotic medicatio…
View article: NCAPG2 Is a Novel Prognostic Biomarker and Promotes Cancer Stem Cell Maintenance in Low-Grade Glioma
NCAPG2 Is a Novel Prognostic Biomarker and Promotes Cancer Stem Cell Maintenance in Low-Grade Glioma Open
Gliomas account for 75% of all primary malignant brain tumors in adults and are associated with high mortality. Mounting evidence has shown that NCAPG2 is differentially expressed in various cancers. However, the prognostic value and immun…
View article: DNA methylation-regulated SNX20 overexpression correlates with poor prognosis, immune cell infiltration, and low-grade glioma progression
DNA methylation-regulated SNX20 overexpression correlates with poor prognosis, immune cell infiltration, and low-grade glioma progression Open
We revealed that SNX20 was up-regulated in LGG, and its higher expression was associated with adverse clinical outcomes and poor clinical characteristics, including WHO grade, IDH mutation, 1p/19q codeletion, and primary therapy outcome. T…
View article: Extra Spindle Pole Bodies-Like 1 Serves as a Prognostic Biomarker and Promotes Lung Adenocarcinoma Metastasis
Extra Spindle Pole Bodies-Like 1 Serves as a Prognostic Biomarker and Promotes Lung Adenocarcinoma Metastasis Open
Extra spindle pole bodies-like 1 (ESPL1), a cysteine endopeptidase, plays a vital role in chromosome inheritance. However, the association of ESPL1 with prognosis and immune infiltration in lung adenocarcinoma (LUAD) has not yet been explo…
View article: DNA methylation-regulated YTHDF2 correlates with cell migration and immune cell infiltration in glioma
DNA methylation-regulated YTHDF2 correlates with cell migration and immune cell infiltration in glioma Open
YTHDF2 correlates with glioma progression and immune cell infiltration, suggesting that YTHDF2 may be a useful prognostic biomarker for glioma.
View article: Long Non-Coding RNA AP000695.2 Acts as a Novel Prognostic Biomarker and Regulates the Cell Growth and Migration of Lung Adenocarcinoma
Long Non-Coding RNA AP000695.2 Acts as a Novel Prognostic Biomarker and Regulates the Cell Growth and Migration of Lung Adenocarcinoma Open
Long non-coding RNAs (lncRNAs) are tumor-associated biological molecules and have been found to be implicated in the progression of lung adenocarcinoma (LUAD). LncRNA-AP000695.2 (ENSG00000248538) is a long non-coding RNA (lncRNA) that is w…
View article: Next-generation sequencing identifies HOXA6 as a novel oncogenic gene in low grade glioma
Next-generation sequencing identifies HOXA6 as a novel oncogenic gene in low grade glioma Open
In conclusion, our data demonstrated that HOXA was correlated with progression and immune infiltration, and could serve as a prognostic biomarker for LGG.
View article: Research progress of Bub3 gene in malignant tumors
Research progress of Bub3 gene in malignant tumors Open
The spindle assembly checkpoint (SAC) is a highly conserved monitoring system that ensures a fidelity of chromosome segregation during mitosis. Bub3, a mitotic Checkpoint Protein, is a member of the Bub protein family, and an important fac…
View article: Combined Transcriptome and Proteome Analysis of Maize (Zea mays L.) Reveals A Complementary Profile in Response to Phosphate Deficiency
Combined Transcriptome and Proteome Analysis of Maize (Zea mays L.) Reveals A Complementary Profile in Response to Phosphate Deficiency Open
A deficiency in the macronutrient phosphate (Pi) brings about various changes in plants at the morphological, physiological and molecular levels. However, the molecular mechanism for regulating Pi homeostasis in response to low-Pi remains …
View article: Genetic architecture of maize yield traits dissected by QTL mapping and GWAS in maize
Genetic architecture of maize yield traits dissected by QTL mapping and GWAS in maize Open
The study of yield traits can reveal the genetic architecture of grain yield for improving maize production. In this study, an association panel comprising 362 inbred lines and a recombinant inbred line population derived from X178 × 9782 …
View article: PirB functions as an intrinsic suppressor in hippocampal neural stem cells
PirB functions as an intrinsic suppressor in hippocampal neural stem cells Open
Neural stem cells play pivotal roles during prenatal development and throughout life. Here, we report that Paired immunoglobulin-like receptor B (PirB) functions as a suppressor during brain neurogenesis in the adult mouse. PirB expression…
View article: Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression
Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression Open
Glioblastoma (GBM) is the most common and malignant primary brain tumor. Glioblastoma stem cells (GSCs) not only initiate and sustain uncontrolled cell proliferation but also resistant to conventional clinical therapies including temozolom…