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View article: Leveraging Large Language Models to Identify Engagement-Driving Features in Vaping-Related TikTok Videos: Cross-Sectional Study
Leveraging Large Language Models to Identify Engagement-Driving Features in Vaping-Related TikTok Videos: Cross-Sectional Study Open
Background Electronic cigarette (e-cigarette) use is prevalent in youth and young adults in the United States. TikTok (ByteDance), a popular social media platform among youth and young adults, has become a key avenue for disseminating e-ci…
View article: Content Analysis of Cannabis Discourses on Twitter/X in the U.S.
Content Analysis of Cannabis Discourses on Twitter/X in the U.S. Open
This study provides a detailed overview of public perceptions of cannabis in the U.S., aiding policymakers and public health authorities in developing effective regulatory policies about cannabis.
View article: Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users
Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users Open
Little is known about how exclusive e-cigarette use affects exosomal microRNA (miRNA) expression, which is crucial in inflammation and disease processes like cancer. We compared exosomal miRNA profiles between exclusive e-cigarette users a…
View article: Public Perceptions of Very Low Nicotine Content on Twitter: Observational Study
Public Perceptions of Very Low Nicotine Content on Twitter: Observational Study Open
Background Nicotine is a highly addictive agent in tobacco products. On June 21, 2022, the US Food and Drug Administration (FDA) announced a plan to propose a rule to establish a maximum nicotine level in cigarettes and other combusted tob…
View article: Temporal and Thematic Analysis of Promotional Waterpipe-Related Posts on Twitter/X in the US
Temporal and Thematic Analysis of Promotional Waterpipe-Related Posts on Twitter/X in the US Open
Introduction Waterpipe tobacco smoking (WTS), also known as hookah, shisha, or narghile, is particularly popular among young people in the United States (US). WTS poses serious health risks similar to those of cigarette smoking. Methods Us…
View article: Public perceptions and discussions of synthetic nicotine on Twitter
Public perceptions and discussions of synthetic nicotine on Twitter Open
Background As alternative replacement products for tobacco-derived nicotine, synthetic nicotine products have recently emerged and gained increasing popularity. This study analyzes public perception and discussion of synthetic nicotine pro…
View article: Public Perceptions of the Food and Drug Administration's Regulatory Authority Over Synthetic Nicotine on Twitter: Observational Study
Public Perceptions of the Food and Drug Administration's Regulatory Authority Over Synthetic Nicotine on Twitter: Observational Study Open
Background The Omnibus Budget Bill, known as H. R. 2471, passed through Congress on March 10, 2022, and was eventually signed by President Biden on March 15, 2022. This bill amended the Federal Food, Drug, and Cosmetic Act granting the Foo…
View article: Public Perceptions and Discussions of the US Food and Drug Administration's JUUL Ban Policy on Twitter: Observational Study
Public Perceptions and Discussions of the US Food and Drug Administration's JUUL Ban Policy on Twitter: Observational Study Open
Background On June 23, 2022, the US Food and Drug Administration announced a JUUL ban policy, to ban all vaping and electronic cigarette products sold by Juul Labs. Objective This study aims to understand public perceptions and discussions…
View article: Public Perception of the Tobacco 21 Amendment on Twitter in the United States: Observational Study
Public Perception of the Tobacco 21 Amendment on Twitter in the United States: Observational Study Open
Background Following the signing of the Tobacco 21 Amendment (T21) in December 2019 to raise the minimum legal age for the sale of tobacco products from 18 to 21 years in the United States, there is a need to monitor public responses and p…
View article: Public perceptions of synthetic cooling agents in electronic cigarettes on Twitter
Public perceptions of synthetic cooling agents in electronic cigarettes on Twitter Open
Amid a potential menthol ban, electronic cigarette (e-cigarette) companies are incorporating synthetic cooling agents like WS-3 and WS-23 to replicate menthol/mint sensations. This study examines public views on synthetic cooling agents in…
View article: Social Network Analysis of e-Cigarette–Related Social Media Influencers on Twitter/X: Observational Study
Social Network Analysis of e-Cigarette–Related Social Media Influencers on Twitter/X: Observational Study Open
Background An e-cigarette uses a battery to heat a liquid that generates an aerosol for consumers to inhale. e-Cigarette use (vaping) has been associated with respiratory disease, cardiovascular disease, and cognitive functions. Recently, …
View article: Characterizing Anti-Vaping Posts for Effective Communication on Instagram Using Multimodal Deep Learning
Characterizing Anti-Vaping Posts for Effective Communication on Instagram Using Multimodal Deep Learning Open
Introduction Instagram is a popular social networking platform for sharing photos with a large proportion of youth and young adult users. We aim to identify key features in anti-vaping Instagram image posts associated with high social medi…
View article: How to Identify e-Cigarette Brands Available in the United States During 2020-2022: Development and Usability Study
How to Identify e-Cigarette Brands Available in the United States During 2020-2022: Development and Usability Study Open
Background Prior studies have demonstrated that the e-cigarette market contains a large number of brands. Identifying these existing e-cigarette brands is a key element of market surveillance, which will further assist in policy making and…
View article: Abnormal expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users
Abnormal expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users Open
Background Exposure to electronic cigarette (e-cigarette) aerosol has been linked to several health concerns, including DNA damage, elevated oxidative stress, the release of inflammatory cytokine, and dysfunctions in epithelial barriers. H…
View article: Public perceptions of the FDA’s marketing authorization of Vuse on Twitter/X
Public perceptions of the FDA’s marketing authorization of Vuse on Twitter/X Open
Introduction On October 12, 2021, the FDA issued its first marketing granted orders for Vuse, the e-cigarette product by R.J. Reynolds Vapor Company. The public perceptions and reactions to the FDA’s Vuse authorization are prevalent on soc…
View article: Public Perception of the Tobacco 21 Amendment on Twitter in the United States: Observational Study (Preprint)
Public Perception of the Tobacco 21 Amendment on Twitter in the United States: Observational Study (Preprint) Open
BACKGROUND Following the signing of the Tobacco 21 Amendment (T21) in December 2019 to raise the minimum legal age for the sale of tobacco products from 18 to 21 years in the United States, there is a need to monitor public responses and …
View article: Social Network Analysis of e-Cigarette–Related Social Media Influencers on Twitter/X: Observational Study (Preprint)
Social Network Analysis of e-Cigarette–Related Social Media Influencers on Twitter/X: Observational Study (Preprint) Open
BACKGROUND An e-cigarette uses a battery to heat a liquid that generates an aerosol for consumers to inhale. e-Cigarette use (vaping) has been associated with respiratory disease, cardiovascular disease, and cognitive functions. Recently,…
View article: Public perceptions of synthetic cooling agents in electronic cigarettes on Twitter
Public perceptions of synthetic cooling agents in electronic cigarettes on Twitter Open
Amid a potential menthol ban, electronic cigarette (e-cigarette) companies are incorporating synthetic cooling agents like WS-3 and WS-23 to replicate menthol/mint sensations. This study examines public views on synthetic cooling agents in…
View article: Public Perceptions and Discussions of the US Food and Drug Administration's JUUL Ban Policy on Twitter: Observational Study (Preprint)
Public Perceptions and Discussions of the US Food and Drug Administration's JUUL Ban Policy on Twitter: Observational Study (Preprint) Open
BACKGROUND On June 23, 2022, the US Food and Drug Administration announced a JUUL ban policy, to ban all vaping and electronic cigarette products sold by Juul Labs. OBJECTIVE This study aims to understand public perceptions and discussi…
View article: Public Perceptions and Discussions of Premium Cigars on Reddit
Public Perceptions and Discussions of Premium Cigars on Reddit Open
Introduction While premium cigars have similar addictive, toxic, and carcinogenic constituents as other cigars and cigarettes, about 1% of the US adults reported premium cigar use from 2010 to 2019. This study aimed to understand public pe…
View article: Potential Impact of the COVID-19 Pandemic on Public Perception of Water Pipes on Reddit: Observational Study
Potential Impact of the COVID-19 Pandemic on Public Perception of Water Pipes on Reddit: Observational Study Open
Background Socializing is one of the main motivations for water pipe smoking. Restrictions on social gatherings during the COVID-19 pandemic might have influenced water pipe smokers’ behaviors. As one of the most popular social media platf…
View article: Public Perceptions of Flavored Waterpipe Smoking on Twitter
Public Perceptions of Flavored Waterpipe Smoking on Twitter Open
Waterpipe tobacco smoking has become increasingly popular in recent years, especially among youth. We aimed to understand longitudinal trends in the prevalence and user perception of waterpipes and their flavors on Twitter. We extracted wa…
View article: How to Identify e-Cigarette Brands Available in the United States During 2020-2022: Development and Usability Study (Preprint)
How to Identify e-Cigarette Brands Available in the United States During 2020-2022: Development and Usability Study (Preprint) Open
BACKGROUND Prior studies have demonstrated that the e-cigarette market contains a large number of brands. Identifying these existing e-cigarette brands is a key element of market surveillance, which will further assist in policy making an…
View article: An evaluation of statistical differential analysis methods in single-cell RNA-seq data
An evaluation of statistical differential analysis methods in single-cell RNA-seq data Open
Background: Single-cell RNA Sequencing is gaining popularity in recent years. Compared to bulk RNA-Seq, single-cell RNA Sequencing allows the gene expression being measured within individual cells instead of mean gene expression levels acr…
View article: Characterizing e-Cigarette–Related Videos on TikTok: Observational Study
Characterizing e-Cigarette–Related Videos on TikTok: Observational Study Open
Background As a popular social networking platform for sharing short videos, TikTok has been widely used for sharing e-cigarettes or vaping-related videos, especially among the youth. Objective This study aims to characterize e-cigarette o…
View article: Public Perceptions of the Food and Drug Administration’s Proposed Rules Prohibiting Menthol Cigarettes on Twitter: Observational Study
Public Perceptions of the Food and Drug Administration’s Proposed Rules Prohibiting Menthol Cigarettes on Twitter: Observational Study Open
Background On April 28, 2022, the Food and Drug Administration (FDA) proposed rules that prohibited all menthol-flavored cigarettes and other flavored cigars to prevent the initiation of tobacco use in youth and reduce tobacco-related dise…
View article: Public Perceptions on the Policy of Electronic Cigarettes as Medical Products on Twitter
Public Perceptions on the Policy of Electronic Cigarettes as Medical Products on Twitter Open
Starting from 1 October 2021, Australia requires a prescription for purchasing nicotine vaping products. On 29 October 2021, the UK provided a guideline to treat e-cigarettes as medical products. This study aims to understand public percep…
View article: Characterizing Heated Tobacco Products Marketing on Instagram: Observational Study
Characterizing Heated Tobacco Products Marketing on Instagram: Observational Study Open
Background Heated tobacco products (HTPs), including I Quit Ordinary Smoking (IQOS), are new tobacco products that use an electronic device to heat compressed tobacco leaves to generate an aerosol for consumers to inhale. Marketing of HTPs…
View article: Monitoring and Identifying Emerging e-Cigarette Brands and Flavors on Twitter: Observational Study
Monitoring and Identifying Emerging e-Cigarette Brands and Flavors on Twitter: Observational Study Open
Background Flavored electronic cigarettes (e-cigarettes) have become very popular in recent years. e-Cigarette users like to share their e-cigarette products and e-cigarette use (vaping) experiences on social media. e-Cigarette marketing a…
View article: Impact of the FDA flavour enforcement policy on flavoured electronic cigarette use behaviour changes
Impact of the FDA flavour enforcement policy on flavoured electronic cigarette use behaviour changes Open
Introduction This study aims to investigate electronic cigarette (e-cigarette) use behaviour changes after the implementation of the US Food and Drug Administration (FDA) restriction on the sale of all unauthorised flavoured cartridge-base…