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View article: Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort
Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort Open
We confirmed cognitive decline in the asymptomatic and prodromal stage of genetic FTD. Specifically, tests for attention, executive function, language, and memory showed clear differences between genetic groups and controls at baseline, bu…
View article: Characterizing the Clinical Features and Atrophy Patterns of <i>MAPT</i> -Related Frontotemporal Dementia With Disease Progression Modeling
Characterizing the Clinical Features and Atrophy Patterns of <i>MAPT</i> -Related Frontotemporal Dementia With Disease Progression Modeling Open
BACKGROUND AND OBJECTIVE: Mutations in the MAPT gene cause frontotemporal dementia (FTD). Most previous studies investigating the neuroanatomical signature of MAPT mutations have grouped all different mutations together and shown an associ…
View article: Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia
Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia Open
The presymptomatic phase of neurodegenerative diseases are characterized by structural brain changes without significant clinical features. We set out to investigate the contribution of functional network resilience to preserved cognition …