Zi‐Li Yu
YOU?
Author Swipe
View article: Macrophage-induced immunomodulation in oral tissue repair and regeneration: Recent advances and future perspectives
Macrophage-induced immunomodulation in oral tissue repair and regeneration: Recent advances and future perspectives Open
Orderly and sequential polarization of macrophages has been proposed as novel immunotherapeutic strategies and promising directions for treating oral diseases. An in-depth exploration of hidden mechanisms may contribute to structural regen…
View article: Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial
Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial Open
FA improved cognitive outcomes in CSVD-CI, accompanied by a reduction in serum Hcy levels and MMP-9 expression. Early FA supplementation could help prevent vascular-related cognitive decline in CSVD-CI patients.
View article: Effect of digital virtual reality simulator on pre-clinical dental surgical skill training: a retrospective study
Effect of digital virtual reality simulator on pre-clinical dental surgical skill training: a retrospective study Open
These findings suggest that DVRS is an effective and beneficial tool for preclinical dental surgical skill training.
View article: The dual effects of macrophage-derived extracellular vesicles on tumor cell behavior: mechanisms and clinical potential
The dual effects of macrophage-derived extracellular vesicles on tumor cell behavior: mechanisms and clinical potential Open
Macrophages, key players in the immune system, exhibit diverse roles in tumor progression and regulation. Macrophages release extracellular vesicles (EVs), membrane-bound particles that facilitate intercellular communication and cargo tran…
View article: Supplementary Data 1 from PERK<sup>+</sup> Macrophages Drive Immunotherapy Resistance in Lymph Node Metastases of Oral Squamous Cell Carcinoma
Supplementary Data 1 from PERK<sup>+</sup> Macrophages Drive Immunotherapy Resistance in Lymph Node Metastases of Oral Squamous Cell Carcinoma Open
Supplementary materials and methods Figure S1 to S17 Table S1 to S7
View article: Data from PERK<sup>+</sup> Macrophages Drive Immunotherapy Resistance in Lymph Node Metastases of Oral Squamous Cell Carcinoma
Data from PERK<sup>+</sup> Macrophages Drive Immunotherapy Resistance in Lymph Node Metastases of Oral Squamous Cell Carcinoma Open
Purpose:Neoadjuvant anti–PD-1 immunotherapy combined with chemotherapy has shown promising pathologic responses in various cancers, including oral squamous cell carcinoma (OSCC). However, the pathologic response of lymph node (LN) metastas…
View article: Immune-featured stromal niches associate with response to neoadjuvant immunotherapy in oral squamous cell carcinoma
Immune-featured stromal niches associate with response to neoadjuvant immunotherapy in oral squamous cell carcinoma Open
Tumor stromal cells (TSCs) play a crucial yet underexplored role in the tumor microenvironment (TME). This study uses single-cell sequencing and spatial transcriptomics on paired tumor specimens from 22 patients with oral squamous cell car…
View article: Identification and management of recurrent oral squamous cell carcinoma in the clinical presentation of osteoradionecrosis: a single-center case series for treatment experience sharing
Identification and management of recurrent oral squamous cell carcinoma in the clinical presentation of osteoradionecrosis: a single-center case series for treatment experience sharing Open
View article: Neoadjuvant immunotherapy with or without chemotherapy in locally advanced oral squamous cell carcinoma: Randomized, two-arm, phase 2 trial
Neoadjuvant immunotherapy with or without chemotherapy in locally advanced oral squamous cell carcinoma: Randomized, two-arm, phase 2 trial Open
Patients with locally advanced oral squamous cell carcinoma (OSCC) have poor outcomes with standard care. Neoadjuvant therapy is shown to be effective for these patients. In the randomized, two-arm, phase 2, non-comparative trial, we inves…
View article: Dual-recognition driven sensing platform based on a BSA-Cu NP nanozyme combined with smartphone-assistance for fluorometric/colorimetric monitoring of dopamine
Dual-recognition driven sensing platform based on a BSA-Cu NP nanozyme combined with smartphone-assistance for fluorometric/colorimetric monitoring of dopamine Open
BSA-Cu NPs with peroxidase-mimicking activity are synthesized for dopamine detection based on fluorometric/colorimetric dual-mode. Besides, by integrating paper strips and smartphone software analysis, an intelligent recognition is also fa…
View article: Research progress on psychological nursing of patients with cancer pain
Research progress on psychological nursing of patients with cancer pain Open
Cancer-related pain, is one of the most common and troublesome symptoms affecting quality of life and mental health of patients with cancer. Psychotherapy is a treatment intervention used to help individuals manage and overcome a range of …
View article: Extracellular vesicle-packaged PD-L1 impedes macrophage-mediated antibacterial immunity in preexisting malignancy
Extracellular vesicle-packaged PD-L1 impedes macrophage-mediated antibacterial immunity in preexisting malignancy Open
Malignancies can compromise systemic innate immunity, but the underlying mechanisms are largely unknown. Here, we find that tumor-derived small extracellular vesicles (sEVs; TEVs) deliver PD-L1 to host macrophages, thereby impeding antibac…
View article: Managing malignant sublingual gland tumors: a single institution experience with 23 patients
Managing malignant sublingual gland tumors: a single institution experience with 23 patients Open
View article: Urease-powered micro/nanomotors: Current progress and challenges
Urease-powered micro/nanomotors: Current progress and challenges Open
Enzyme-powered micro/nanomotors (MNMs) (EMNMs) use natural enzymes to facilitate the decomposition of fuels, including hydrogen peroxide (H2O2), glucose, triglycerides, and urea to provide power. EMNMs can achieve sel…
View article: Multi-factor early monitoring method based on D-dimer for iliac crest flap loss
Multi-factor early monitoring method based on D-dimer for iliac crest flap loss Open
Our study illustrates that postoperative plasma D-dimer levels can serve as a sensitive biomarker for monitoring thrombosis-induced flap loss. Moreover, we have developed a novel prediction model that integrates multiple factors, thereby e…
View article: Application of Digital Virtual Reality Simulator for Dental Surgical Skill Training
Application of Digital Virtual Reality Simulator for Dental Surgical Skill Training Open
Aim Dental surgical skills training assumes critical importance for aspiring dentists. Our present study aimed to investigate the effectiveness of innovative DVRS approach in preclinical dental surgical skill training. Methods A total of 1…
View article: EGFR Mutation and TKI Treatment Promote Secretion of Small Extracellular Vesicle PD-L1 and Contribute to Immunosuppression in NSCLC
EGFR Mutation and TKI Treatment Promote Secretion of Small Extracellular Vesicle PD-L1 and Contribute to Immunosuppression in NSCLC Open
In Asian populations with non-small-cell lung cancer (NSCLC), EGFR mutations are highly prevalent, occurring in roughly half of these patients. Studies have revealed that individuals with EGFR mutation typically fare worse with immunothera…
View article: Correction to “Magnetic and Folate Functionalization Enables Rapid Isolation and Enhanced Tumor-Targeting of Cell-Derived Microvesicles”
Correction to “Magnetic and Folate Functionalization Enables Rapid Isolation and Enhanced Tumor-Targeting of Cell-Derived Microvesicles” Open
ADVERTISEMENT RETURN TO ARTICLES ASAPPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Magnetic and Folate Functionalization Enables Rapid Isolation and Enhanced Tumor-Targeting of Cell-Derived Microvesic…
View article: D-dimer-based prediction model for flap loss in iliac bone transplantation
D-dimer-based prediction model for flap loss in iliac bone transplantation Open
Background: In recent years, the utilization of autogenous vascularized iliac crest flap for repairing jaw defects has seen a significant rise. However, the visual monitoring of iliac bone grafts presents challenges, frequently leading to …
View article: PD-1/CD80+ small extracellular vesicles from immunocytes induce cold tumours featured with enhanced adaptive immunosuppression
PD-1/CD80+ small extracellular vesicles from immunocytes induce cold tumours featured with enhanced adaptive immunosuppression Open
Only a minority of cancer patients benefit from immune checkpoint blockade therapy. Sophisticated cross-talk among different immune checkpoint pathways as well as interaction pattern of immune checkpoint molecules carried on circulating sm…
View article: Algorithm for the reconstruction of the parotid region: a single institution experience
Algorithm for the reconstruction of the parotid region: a single institution experience Open
Objective This study aims to discuss the characteristics and treatment methods of malignant tumors in the parotid region, as well as the therapeutic effects of immediate free flap reconstruction of soft tissue for postoperative defects. Ma…
View article: Antibacterial micro/nanomotors: current research progress, challenges, and opportunities
Antibacterial micro/nanomotors: current research progress, challenges, and opportunities Open
Bacterial infections remain a formidable threat to human health, a situation exacerbated by the escalating problem of antibiotic resistance. While alternative antibacterial strategies such as oxidants, heat treatments, and metal nanopartic…
View article: Exosomal DNA: Role in Reflecting Tumor Genetic Heterogeneity, Diagnosis, and Disease Monitoring
Exosomal DNA: Role in Reflecting Tumor Genetic Heterogeneity, Diagnosis, and Disease Monitoring Open
Extracellular vesicles (EVs), with exosomes at the forefront, are key in transferring cellular information and assorted biological materials, including nucleic acids. While exosomal RNA has been thoroughly examined, exploration into exosom…
View article: Extracellular vesicles in anti-tumor drug resistance: Mechanisms and therapeutic prospects
Extracellular vesicles in anti-tumor drug resistance: Mechanisms and therapeutic prospects Open
View article: Red Blood Cell-Derived Extracellular Vesicles: An Overview of Current Research Progress, Challenges, and Opportunities
Red Blood Cell-Derived Extracellular Vesicles: An Overview of Current Research Progress, Challenges, and Opportunities Open
Red blood cell-derived extracellular vesicles (RBC EVs) are small, spherical fragments released from red blood cells. These vesicles, similar to EVs derived from other cell types, are crucial for intercellular communication processes and h…
View article: Identification of SEC61G as a Diagnostic and Prognostic Biomarker in Oral Squamous Cell Carcinoma
Identification of SEC61G as a Diagnostic and Prognostic Biomarker in Oral Squamous Cell Carcinoma Open
Oral squamous cell carcinoma (OSCC) is a heterogeneous malignancy originating from the oral mucosal epithelium. Detecting novel biomarkers can offer crucial information on disease aggressiveness and expected clinical outcomes for individua…
View article: Immunosuppressive effect of small extracellular vesicle PD-L1 is restricted by co-expression of CD80
Immunosuppressive effect of small extracellular vesicle PD-L1 is restricted by co-expression of CD80 Open
View article: Anti-Tumor Strategies by Harnessing the Phagocytosis of Macrophages
Anti-Tumor Strategies by Harnessing the Phagocytosis of Macrophages Open
Macrophages are essential for the human body in both physiological and pathological conditions, engulfing undesirable substances and participating in several processes, such as organism growth, immune regulation, and maintenance of homeost…
View article: Extracellular vesicles in tumor angiogenesis and resistance to anti‐angiogenic therapy
Extracellular vesicles in tumor angiogenesis and resistance to anti‐angiogenic therapy Open
Tumor angiogenesis plays an important role in the development of cancer as it allows the delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant organs. Although anti‐angiogenic therapy (AAT) has been ap…
View article: Real‐Time Dissection of the Transportation and miRNA‐Release Dynamics of Small Extracellular Vesicles (Adv. Sci. 7/2023)
Real‐Time Dissection of the Transportation and miRNA‐Release Dynamics of Small Extracellular Vesicles (Adv. Sci. 7/2023) Open
Single Particle Tracking of Extracellular Vesicles In article number 2205566, by developing a quantum dot‐assisted single particle tracking platform, Wei Zhang, Dai‐Wen Pang, Gang Chen, and co‐workers tracked the three‐stage transportation…