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View article: Myeloid-driven immunosuppression in head and neck cancer: single-cell ATAC/RNA and spatial transcriptomic perspectives
Myeloid-driven immunosuppression in head and neck cancer: single-cell ATAC/RNA and spatial transcriptomic perspectives Open
Head and neck squamous cell carcinoma (HNSCC) remains a prevalent epithelial malignancy. Immune-checkpoint inhibitors have reshaped first-line therapy for recurrent/metastatic disease; yet durable benefit is confined to a subset, reflectin…
View article: A Global Bibliometric Study of Current Bladder Cancer Cell Death Research
A Global Bibliometric Study of Current Bladder Cancer Cell Death Research Open
Cell death mechanisms offer therapeutic strategies for bladder cancer, yet lack comprehensive bibliometric analysis. Map global research trends and hotspots in bladder cancer cell death mechanisms via bibliometrics. We analyzed 5,392 publi…
Origin and Evolution of Momentum: A Literature Review Open
The multi-factor models are playing an indispensable role in understanding the systematic risk and the market perception of value across assets. Within the zoo of factors, the momentum factor and the robustness of its associated returns ha…
Structure Evolution of Organic Luminescent Molecules Utilizing Through‐Space Charge Transfer Mechanism Open
Organic structures provide an extensive platform for luminescent materials thanks to the easy to design and synthesize, low toxicity and tunable functionalization. Through‐space charge transfer (TSCT) in organic molecules, characterized by…
Ring-in-Ring Assembly Facilitates the Synthesis of a Cyclopara-phenylene Hetero[3]Catenane Open
Cycloparaphenylenes (CPPs) represent a significant challenge for the synthesis of mechanically interlocked architectures, because they lack heteroatoms, which precludes traditional active and passive template methods. To circumvent this pr…
Homochiral π‐Rich Covalent Organic Frameworks Enabled Chirality Imprinting in Conjugated Polymers: Confined Polymerization and Chiral Memory from Scratch Open
Optically active π‐conjugated polymers (OACPs) have garnered increasing research interest for their resemblance to biological helices and intriguing chirality‐related functions. Traditional methods for synthesizing involve decorating achir…
Chiral Dual Core Chromophores Based on Binaphthyl Acrylonitrile Motif with Tunable Dual Emission Bands and Anti‐counterfeiting Open
Small organic molecules which can emit fluorescence with tunable dual emission bands are significant for fundamental research and broad applications. In this work, two binaphthyl based arylacrylonitrile derivatives with pyrene and tripheny…
View article: AgNTf<sub>2</sub>-catalyzed formal [3 + 2] cycloaddition of ynamides with unprotected isoxazol-5-amines: efficient access to functionalized 5-amino-1<i>H</i>-pyrrole-3-carboxamide derivatives
AgNTf<sub>2</sub>-catalyzed formal [3 + 2] cycloaddition of ynamides with unprotected isoxazol-5-amines: efficient access to functionalized 5-amino-1<i>H</i>-pyrrole-3-carboxamide derivatives Open
A formal [3 + 2] cycloaddition between ynamides and unprotected isoxazol-5-amines has been developed in the presence of catalytic AgNTf 2 in an open flask. By the protocol, a variety of functionalized 5-amino-1 H -pyrrole-3-carboxamide der…
View article: Synthesis of 4-(1<i>H</i>-isochromen-1-yl)isoquinolines through the silver-catalysed homodimerization of <i>ortho</i>-alkynylarylaldehydes and subsequent condensation of the 1,5-dicarbonyl motif with NH<sub>3</sub>
Synthesis of 4-(1<i>H</i>-isochromen-1-yl)isoquinolines through the silver-catalysed homodimerization of <i>ortho</i>-alkynylarylaldehydes and subsequent condensation of the 1,5-dicarbonyl motif with NH<sub>3</sub> Open
We demonstrate a strategy that can provide isochromenes with an electron-deficient isoquinoline unit. The reactions feature simple operations, mild conditions and high yields.
Reversibility of imido-based ionic liquids: a theoretical and experimental study Open
Theoretical and experimental methods were used to study the reversibility of a series of imido-based ionic liquids.
Green synthesis of 1-phenyl-1-ortho-xylene ethane in IL and reaction mechanism Open
In this study, 1-phenyl-1-ortho-xylene ethane (PXE) is synthesized in IL and the catalysts used were AlCl3 in 1-butyl-3-methylimidazolium bromide ([BMIM][Br]) or 1-butyl-3-methylimidazolium chloride ([BMIM][Cl]).
Bright and sensitive ratiometric fluorescent probe enabling endogenous FA imaging and mechanistic exploration of indirect oxidative damage due to FA in various living systems Open
Herein, we present the design and multi-application of a bright and sensitive ratiometric fluorescent probe,PIPBA, for the imaging of formaldehyde (FA) in living systems.