Ziqiang Zhang
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View article: A tailored <i>in vivo</i> CRISPR screen identifies <i>BAP1</i> as a potent tumor suppressor of soft tissue sarcoma
A tailored <i>in vivo</i> CRISPR screen identifies <i>BAP1</i> as a potent tumor suppressor of soft tissue sarcoma Open
Undifferentiated pleomorphic sarcoma (UPS) is one of the most common soft tissue sarcomas (STS) in adults. Despite decades of research, therapeutic advancements for STS, including UPS, have remained limited. The genetic complexity of UPS, …
View article: Physical Exercise and Behavioral Addiction: How Self-Control and Subjective Emptiness Jointly Mediate the Reduction of Short-Video Addiction in Adolescents
Physical Exercise and Behavioral Addiction: How Self-Control and Subjective Emptiness Jointly Mediate the Reduction of Short-Video Addiction in Adolescents Open
Background: Short-video addiction is prevalent among adolescents and threatens their development. This study aimed to examine the relationships among physical exercise, self-control, subjective emptiness, and short-video addiction in adole…
View article: Association between statin use and the risk of atrial fibrillation in community-dwelling older people in Shanghai, China: a propensity score-matched study
Association between statin use and the risk of atrial fibrillation in community-dwelling older people in Shanghai, China: a propensity score-matched study Open
For older people, taking statins did not reduce risk of new on-set AF. Independent predictors of AF onset including age, SBP, BMI, HbA1c and Scr. This is a retrospective cohort study, making it difficult to completely control for all confo…
View article: Chaperone nanomotors with chemotactic ability for the treatment of Parkinson’s disease
Chaperone nanomotors with chemotactic ability for the treatment of Parkinson’s disease Open
Aggregation of α-synuclein (α-syn) represents a pathogenic hallmark of Parkinson’s disease (PD). Using exogenous molecular chaperone systems has the potential to stabilize native conformations and inhibit the aberrant aggregation of α-syn,…
View article: Mechanical design and motion planning of a centipede-inspired robot
Mechanical design and motion planning of a centipede-inspired robot Open
View article: Design, Analysis, and Experiment of an Automatic Lettuce-Harvesting Mechanism
Design, Analysis, and Experiment of an Automatic Lettuce-Harvesting Mechanism Open
The global reduction in agricultural labor owing to rural depopulation and an aging workforce necessitates advancements in agricultural automation. This paper presents the design, optimization, and experimental validation of an innovative …
View article: Evaluating Key Spatial Indicators for Shared Autonomous Vehicle Integration in Old Town Spaces
Evaluating Key Spatial Indicators for Shared Autonomous Vehicle Integration in Old Town Spaces Open
As Shared Autonomous Vehicles (SAVs) emerge as a transformative force in urban mobility, integrating them into dense, historic urban environments presents distinct spatial and planning challenges—such as narrow street patterns, irregular r…
View article: The role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration
The role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration Open
View article: Research on the influence of bionic textures on the lubrication efficiency and loss power of spur gears
Research on the influence of bionic textures on the lubrication efficiency and loss power of spur gears Open
Focused on the lubrication optimization challenge in gear transmission systems, this paper introduces a novel approach involving the coordinated adjustment of bionic textures and nozzle arrangement. By analyzing the surface texture charact…
View article: Influence of texture parameters based on particle swarm optimization on tooth surface pressure of gears
Influence of texture parameters based on particle swarm optimization on tooth surface pressure of gears Open
The MPS particle method is employed to simulate the tooth surface pressure of textured gears. Among these, the NO114 gear exhibited the lowest tooth surface pressure. However, the lubrication performance achieved using empirically designed…
View article: MEASUREMENT OF NATURAL FREQUENCY OF THE CLAMPED BEAM BASED ON FIBER BRAGG GRATINGS SENSOR
MEASUREMENT OF NATURAL FREQUENCY OF THE CLAMPED BEAM BASED ON FIBER BRAGG GRATINGS SENSOR Open
View article: Bidirectional Adaptation of Shared Autonomous Vehicles and Old Towns’ Urban Spaces: The Views of Residents on the Present
Bidirectional Adaptation of Shared Autonomous Vehicles and Old Towns’ Urban Spaces: The Views of Residents on the Present Open
The integration of shared autonomous vehicles into historic urban areas presents both opportunities and challenges. In heritage-rich environments like very old Asian (such as Suzhou old town, which serves as a use case example) or European…
View article: α‐Diimine Nickel Catalyst with Remote Rigid Spatial Hindrance for the Synthesis of Polyolefin Elastomers
α‐Diimine Nickel Catalyst with Remote Rigid Spatial Hindrance for the Synthesis of Polyolefin Elastomers Open
Recently, it has been discovered that α‐diimine nickel catalysts have potential in the preparation of polyolefin elastomers using ethylene as the only raw material. By adjusting the steric hindrance and electronic effect of ligands, the pe…
View article: Correction: Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer
Correction: Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer Open
View article: Bacillus coagulans alleviates hepatic injury caused by Klebsiella pneumoniae in rabbits
Bacillus coagulans alleviates hepatic injury caused by Klebsiella pneumoniae in rabbits Open
Background As an opportunistic bacterial pathogen, Klebsiella pneumoniae (KP) is prone to causing a spectrum of diseases in rabbits when their immune system is compromised, which poses a threat to rabbit breeding industry. Bacillus coagula…
View article: Enhanced Shear Strength Prediction for Frp-Reinforced Concrete Beams: Synergistic Effects of Multiple Variables and New Empirical Models
Enhanced Shear Strength Prediction for Frp-Reinforced Concrete Beams: Synergistic Effects of Multiple Variables and New Empirical Models Open
View article: Research on the Entrance Damage of Carbon Fiber-Reinforced Polymer/Ti6Al4V Stacks in Six-Degrees-of-Freedom Robot Drilling
Research on the Entrance Damage of Carbon Fiber-Reinforced Polymer/Ti6Al4V Stacks in Six-Degrees-of-Freedom Robot Drilling Open
Carbon fiber-reinforced polymer (CFRP)/titanium alloy (Ti6Al4V) stacks are widely used in the aerospace industry due to their excellent physical properties. The substantial demand for drilling components in the aerospace industry necessita…
View article: Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567]
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567] Open
[This corrects the article DOI: 10.1016/j.gendis.2022.02.014.].
View article: High sensitivity strain and refractive index MZI-SPR sensing based on dual fiber winding structure
High sensitivity strain and refractive index MZI-SPR sensing based on dual fiber winding structure Open
Fiber strain and refractive index dual parameter sensor have enormous potential in the field of underwater structural health monitoring. This article proposes a strain and refractive index highly sensitive MZI-SPR composite sensor based on…
View article: Wave type fiber SPR sensor for rapid and highly sensitive detection of hyperoside
Wave type fiber SPR sensor for rapid and highly sensitive detection of hyperoside Open
The fiber surface plasmon resonance (SPR) sensor used for the detection of active ingredients in traditional Chinese medicine has the problems of low sensitivity and difficult specific recognition. This paper proposed a wave type fiber SPR…
View article: Association between Statin use and the risk of atrial fibrillation in community-dwelling older people in Shanghai, China：a propensity score-matched study
Association between Statin use and the risk of atrial fibrillation in community-dwelling older people in Shanghai, China：a propensity score-matched study Open
Objective: Whether statins prevent atrial fibrillation remains unclear. In particular, the data on the elderly are limited. Thus we investigated the association between statin use and the risk of atrial fibrillation (AF) in community-dwell…
View article: Computer aided design of a single degree-of-freedom six-bar mechanism via Monte Carlo layered optimization method
Computer aided design of a single degree-of-freedom six-bar mechanism via Monte Carlo layered optimization method Open
Planar single degree of freedom (DOF) 6-bar mechanisms, characterized by simple control and high stiffness, find extensive applications across various robotic systems. Nevertheless, the augmented quantity of design variables presents chall…
View article: Large detection range and high strain sensitivity fiber SPR sensor based on wave structure
Large detection range and high strain sensitivity fiber SPR sensor based on wave structure Open
To achieve a fiber strain sensor with a large detection range and high sensitivity, this paper proposes a wave structured fiber SPR strain sensor. When subjected to axial strain, the wave structured fiber is stretched axially, increasing t…
View article: Spatial-Contextual Discrepancy Information Compensation for GAN Inversion
Spatial-Contextual Discrepancy Information Compensation for GAN Inversion Open
Most existing GAN inversion methods either achieve accurate reconstruction but lack editability or offer strong editability at the cost of fidelity. Hence, how to balance the distortion-editability trade-off is a significant challenge for …
View article: Spiral cone fiber SPR sensor for detecting ginsenoside Rg1
Spiral cone fiber SPR sensor for detecting ginsenoside Rg1 Open
The conical fiber SPR sensor is easy to manufacture and has been used in biochemical detection research, but it has the problem of structural fragility. This article proposes a spiral cone fiber SPR sensor, which introduces a spiral struct…
View article: Study on the Process Optimization of Peanut Coat Pigment Staining of Poplar Wood
Study on the Process Optimization of Peanut Coat Pigment Staining of Poplar Wood Open
Wood staining is a crucial technique for enhancing the decorative effect of wood. Different mordants and mordant processes can influence the staining effect of wood. In this study, three types of mordants and mordant methods were selected …
View article: Experimental study on rotary longitudinal-torsional ultrasonic machining of unidirectional CFRP
Experimental study on rotary longitudinal-torsional ultrasonic machining of unidirectional CFRP Open
Addressing the challenges of high grinding temperature, poor hole quality, and tool rod blocking in core drilling of carbon fiber reinforced plastics (CFRP), this study investigates the material removal characteristic of rotary longitudina…
View article: Effect of ultrasonic vibration on oxide layer properties in ultrasonic-assisted ELID internal cylinder grinding
Effect of ultrasonic vibration on oxide layer properties in ultrasonic-assisted ELID internal cylinder grinding Open
The oxide film on the surface of the grinding wheel plays a very important role in ultrasonic-assisted electrolytic in-process dressing (UA-ELID) grinding. In order to investigate the influence of ultrasonic vibration on the characteristic…
View article: Soft Template-Induced Self-Assembly Strategy for Sustainable Production of Porous Carbon Spheres as Anode Towards Advanced Sodium-Ion Batteries
Soft Template-Induced Self-Assembly Strategy for Sustainable Production of Porous Carbon Spheres as Anode Towards Advanced Sodium-Ion Batteries Open
View article: Effect of the Sr–Fe layered double hydroxide coating based on the microenvironment response on implant osseointegration in osteoporotic rats
Effect of the Sr–Fe layered double hydroxide coating based on the microenvironment response on implant osseointegration in osteoporotic rats Open
Sr–Fe LDH coating promotes osteoblastic bone formation and inhibits osteoclastic bone resorption, resulting increased mechanical stability, peripheral bone mass, and osseointegration of implants in osteoporotic rats.