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View article: Large Language Models Achieve Gold Medal Performance at the International Olympiad on Astronomy & Astrophysics (IOAA)
Large Language Models Achieve Gold Medal Performance at the International Olympiad on Astronomy & Astrophysics (IOAA) Open
While task-specific demonstrations show early success in applying large language models (LLMs) to automate some astronomical research tasks, they only provide incomplete views of all necessary capabilities in solving astronomy problems, ca…
View article: Early prediction of bloodstream infections in ICU patients using machine learning methods based on routine laboratory parameters
Early prediction of bloodstream infections in ICU patients using machine learning methods based on routine laboratory parameters Open
Background Bloodstream infections (BSIs) are a major cause of morbidity and mortality in Intensive Care Units (ICUs). Although blood cultures remain the diagnostic gold standard, their long turnaround time may hinder early risk warning. Ea…
View article: First Observation of Quantum Correlations in <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msup><mml:mi>e</mml:mi><mml:mo>+</mml:mo></mml:msup><mml:msup><mml:mi>e</mml:mi><mml:mo>−</mml:mo></mml:msup><mml:mo stretchy="false">→</mml:mo><mml:mi>X</mml:mi><mml:mi>D</mml:mi><mml:mover accent="true"><mml:mi>D</mml:mi><mml:mo stretchy="true">¯</mml:mo></mml:mover></mml:math> and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>C</mml:mi></mml:math>-Even Constrained <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>D</mml:mi><mml:mover accent="true"><mml:mrow><mml:mi>D</mml:mi></mml:mrow><mml:mrow><mml:mo stretchy="true">¯</mml:mo></mml:mrow></mml:mover></mml:mrow></mml:math> Pairs
First Observation of Quantum Correlations in and -Even Constrained Pairs Open
The study of meson pairs produced with quantum correlations gives direct access to parameters that are challenging to measure in other systems. In this Letter, the existence of quantum correlations due to charge-conjugation symmetry C are …
View article: Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers Open
The therapeutic benefit of recently developed mutant KRAS (KRAS∗) inhibitors remains limited by the rapid onset of resistance. Here, we aim to delineate mechanisms underlying acquired resistance and identify actionable targets for overcomi…
View article: Hearing Intervention, Social Isolation, and Loneliness
Hearing Intervention, Social Isolation, and Loneliness Open
Importance Promoting social connection among older adults is a public health priority. Addressing hearing loss may reduce social isolation and loneliness among older adults. Objective To describe the effect of a best-practice hearing inter…
View article: Elliptic and Triangular Flow of Quark-Gluon Plasma in Pb+Pb Collisions in the sPHENIX detector
Elliptic and Triangular Flow of Quark-Gluon Plasma in Pb+Pb Collisions in the sPHENIX detector Open
This paper presents the analysis of the hydrodynamic properties of Quark-Gluon Plasma (QGP) in PbPb collision events collected by the sPHENIX detector, focusing on the elliptic flow () and triangular flow () by analyzing azimuthal angle di…
View article: Therapeutic targeting of Syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
Therapeutic targeting of Syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers Open
The therapeutic benefit of recently developed mutant KRAS (mKRAS) inhibitors has been limited by the rapid onset of resistance. Here, we aimed to delineate the mechanisms underlying acquired resistance to mKRAS inhibition and identify acti…
View article: Clonal dominance defines metastatic dissemination in pancreatic cancer
Clonal dominance defines metastatic dissemination in pancreatic cancer Open
Tumors represent ecosystems where subclones compete during tumor growth. While extensively investigated, a comprehensive picture of the interplay of clonal lineages during dissemination is still lacking. Using patient-derived pancreatic ca…
View article: RDMS: Reverse Distillation with Multiple Students of Different Scales for Anomaly Detection
RDMS: Reverse Distillation with Multiple Students of Different Scales for Anomaly Detection Open
Unsupervised anomaly detection is a critical task in computer vision, often approached as a one-class classification problem. Knowledge distillation has shown promising results in this area, particularly with the emergence of reverse disti…
View article: SMARCB1 regulates the hypoxic stress response in sickle cell trait
SMARCB1 regulates the hypoxic stress response in sickle cell trait Open
Renal medullary carcinoma (RMC) is an aggressive kidney cancer that almost exclusively develops in individuals with sickle cell trait (SCT) and is always characterized by loss of the tumor suppressor SMARCB1 . Because renal ischemia induce…
View article: Timing Performance of the CMS High Granularity Calorimeter Prototype
Timing Performance of the CMS High Granularity Calorimeter Prototype Open
This paper describes the experience with the calibration, reconstruction and evaluation of the timing capabilities of the CMS HGCAL prototype in the beam tests in 2018. The calibration procedure includes multiple steps and corrections rang…
View article: Further fine mapping and candidate gene prediction for a new restoring fertility gene Rf(fa) in rice
Further fine mapping and candidate gene prediction for a new restoring fertility gene Rf(fa) in rice Open
Rf(fa), a new restoring fertility gene in rice, was previously located to a large region on Chromosome 10. The large number of genes within the region made cloning of Rf(fa) difficult. To perform the cloning and further elucidate the molec…
View article: SMARCB1 regulates the hypoxic stress response in sickle cell trait during the pathogenesis of renal medullary carcinoma.
SMARCB1 regulates the hypoxic stress response in sickle cell trait during the pathogenesis of renal medullary carcinoma. Open
SMARCB1 is one of the core subunits of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex.• Malignancies are characterized by simple genomes and lack of somatic events, suggesting that the dysregulation of the SWI/SNF machi…
View article: AdaLoGN: Adaptive Logic Graph Network for Reasoning-Based Machine Reading Comprehension
AdaLoGN: Adaptive Logic Graph Network for Reasoning-Based Machine Reading Comprehension Open
Recent machine reading comprehension datasets such as ReClor and LogiQA require performing logical reasoning over text. Conventional neural models are insufficient for logical reasoning, while symbolic reasoners cannot directly apply to te…
View article: CLUE: A Fast Parallel Clustering Algorithm for High Granularity Calorimeters in High-Energy Physics
CLUE: A Fast Parallel Clustering Algorithm for High Granularity Calorimeters in High-Energy Physics Open
One of the challenges of high granularity calorimeters, such as that to be built to cover the endcap region in the CMS Phase-2 Upgrade for HL-LHC, is that the large number of channels causes a surge in the computing load when clustering nu…
View article: GPU-based Clustering Algorithm for the CMS High Granularity Calorimeter
GPU-based Clustering Algorithm for the CMS High Granularity Calorimeter Open
The future High Luminosity LHC (HL-LHC) is expected to deliver about 5 times higher instantaneous luminosity than the present LHC, resulting in pile-up up to 200 interactions per bunch crossing (PU200). As part of the phase-II upgrade prog…
View article: Visualization of Reconstruction of CMS HGCal
Visualization of Reconstruction of CMS HGCal Open
This is a visualization of an event reconstructed in CMS HGCal. This event is consist of 10 pions with a transverse momentum of 35 GeV. The reconstruction algorithm groups all valid energy deposits (hits) into clusters, each incoming parti…
View article: Offline Reconstruction Algorithms for the CMS High Granularity Calorimeter for HL-LHC
Offline Reconstruction Algorithms for the CMS High Granularity Calorimeter for HL-LHC Open
The upgraded High Luminosity LHC, after the third Long Shutdown (LS3), will provide an instantaneous luminosity of $7.5 \\times 10^{34}$ cm$^{-2}$ s$^{-1}$ (levelled), at the price of extreme pileup of up to 200 interactions per crossing. …