Zixiang Guo
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View article: Porphyromonas gingivalis induces Zbp1-mediated macrophages PANoptosis in periodonitis pathophysiology
Porphyromonas gingivalis induces Zbp1-mediated macrophages PANoptosis in periodonitis pathophysiology Open
Periodontitis is an oral immunoinflammatory disease, and macrophages play a crucial role in its pathophysiology. However, macrophage death during antibacterial activities will exacerbate inflammation and tissue damage. Porphyromonas gingiv…
View article: Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence
Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence Open
MCPH1 has been identified as the causal gene for primary microcephaly type 1, a neurodevelopmental disorder characterized by reduced brain size and delayed growth. As a multifunction protein, MCPH1 has been reported to repress the expressi…
View article: A nomogram based on the log odds of positive lymph nodes for predicting the prognosis of T1 stage rectal cancer.
A nomogram based on the log odds of positive lymph nodes for predicting the prognosis of T1 stage rectal cancer. Open
Early detection and timely treatment is the key to improving the prognosis of rectal cancer. Lymph node metastasis is one of the reasons for the poor prognosis of rectal cancer, especially early-stage rectal cancer. In this study, we devel…
View article: Analysis of the timing of endoscopic treatment for esophagogastric variceal bleeding in cirrhosis
Analysis of the timing of endoscopic treatment for esophagogastric variceal bleeding in cirrhosis Open
Background Existing guidelines recommend endoscopic treatment within 12 h or 12–24 h for patients with esophagogastric variceal bleeding (EGVB) in cirrhosis. In addition, research findings on the optimal time for endoscopy are inconsistent…
View article: Development and validation of a prognostic nomogram for bone metastasis from lung cancer: A large population-based study
Development and validation of a prognostic nomogram for bone metastasis from lung cancer: A large population-based study Open
Background Bone is one of the most common metastatic sites of advanced lung cancer, and the median survival time is significantly shorter than that of patients without metastasis. This study aimed to identify prognostic factors associated …
View article: Combination RSL3 Treatment Sensitizes Ferroptosis- and EGFR-Inhibition-Resistant HNSCCs to Cetuximab
Combination RSL3 Treatment Sensitizes Ferroptosis- and EGFR-Inhibition-Resistant HNSCCs to Cetuximab Open
Head and neck squamous cell carcinomas (HNSCCs) are a type of cancer originating in the mucosal epithelium of the mouth, pharynx, and larynx, the sixth most common cancer in the world. However, there is no effective treatment for HNSCCs. M…
View article: Preparation and Characterization of Stellera Chamaejasme-Based Carbon Molecular Sieves
Preparation and Characterization of Stellera Chamaejasme-Based Carbon Molecular Sieves Open
The activation effect of boric acid as an activator is good, and we investigate the best activation conditions for the boric acid impregnation method. To represent the structural characteristics and adsorption performance of the Stellera C…
View article: Experimental Investigations and Quantum−Chemical Calculations of Isocyanate-Based Chemically Modified Bitumen And its Crosslinking Behaviours
Experimental Investigations and Quantum−Chemical Calculations of Isocyanate-Based Chemically Modified Bitumen And its Crosslinking Behaviours Open