Zi-Xiang Yu
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View article: Genetic and Epigenetic Regulation of Inflammatory Genes Drives Calcific Aortic Valve Disease (CAVD)
Genetic and Epigenetic Regulation of Inflammatory Genes Drives Calcific Aortic Valve Disease (CAVD) Open
Introduction Calcific aortic valve disease (CAVD) is the most common valvular disorder in older adults, characterized by progressive fibrosis, calcification, and impaired blood flow. Despite its growing burden, no effective pharmacological…
View article: Enhancing Preservice Teachers’ Use of Dialogic Teaching and Dynamic Visualizations in Mathematics Classes: Bridging the Knowing–Doing Gap
Enhancing Preservice Teachers’ Use of Dialogic Teaching and Dynamic Visualizations in Mathematics Classes: Bridging the Knowing–Doing Gap Open
Talking productively with students and sufficiently integrating technology into mathematics classrooms have long been regarded as two hurdles for mathematics teachers. To enhance preservice mathematics teachers’ dialogic teaching skills an…
View article: The role of advanced glycation end products between thyroid function and diabetic nephropathy and metabolic disorders
The role of advanced glycation end products between thyroid function and diabetic nephropathy and metabolic disorders Open
The findings suggest that HRFs such as HDL, TyG and TC should be prioritized when evaluating indicators related to DN to effectively reduce DN in Chinese patients with high health risk levels. Comprehensive indicators may be an effective a…
View article: Totally Thoracoscopic Treatment of Cardiac Myxoma: Experience from 29 Cases and Review of the Literature
Totally Thoracoscopic Treatment of Cardiac Myxoma: Experience from 29 Cases and Review of the Literature Open
Background: Cardiac myxoma, a rare benign tumor, can cause significant patient morbidity if left untreated. Traditionally, treatment has involved open sternotomy; however, recent advancements now enable minimally invasive resection using t…
View article: Evaluation of the Efficacy of Transcatheter Intervention, Surgery, and Pharmacological Treatment of Functional Mitral Regurgitation — A Bayesian Network Meta-Analysis with ≥12-Month Follow-up
Evaluation of the Efficacy of Transcatheter Intervention, Surgery, and Pharmacological Treatment of Functional Mitral Regurgitation — A Bayesian Network Meta-Analysis with ≥12-Month Follow-up Open
Aim: Evaluate, using a Bayesian network meta-analysis system, the long-term prognosis of patients with functional mitral regurgitation (FMR) undergoing individual or combined treatment with percutaneous intervention, surgical intervention,…
View article: Unravelling the Difference of Immune Microenvironment Characteristics between Esophageal Basaloid Squamous Cell Carcinoma and Conventional Esophageal Squamous Cell Carcinoma
Unravelling the Difference of Immune Microenvironment Characteristics between Esophageal Basaloid Squamous Cell Carcinoma and Conventional Esophageal Squamous Cell Carcinoma Open
View article: Impact of ternary NADES prepared from proline, glucose and water on the Maillard reaction: Reaction activity, Amadori compound yield, and taste-enhancing ability
Impact of ternary NADES prepared from proline, glucose and water on the Maillard reaction: Reaction activity, Amadori compound yield, and taste-enhancing ability Open
View article: The Correlation Between Health Risk Factors and Diabesity and Lipid Profile Indicators: The Role Mediator of TSH
The Correlation Between Health Risk Factors and Diabesity and Lipid Profile Indicators: The Role Mediator of TSH Open
Our findings suggest that the quality of metabolic-related indicators used to successfully decrease diabetes in Chinese individuals with high HRFs levels should be prioritized. Comprehensive indicators might be a useful and practical way f…
View article: Effects of Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting on Clinical Outcomes in Patients with Reduced Ejection Fraction Heart Failure and Coronary Heart Disease: A Meta-Analysis
Effects of Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting on Clinical Outcomes in Patients with Reduced Ejection Fraction Heart Failure and Coronary Heart Disease: A Meta-Analysis Open
Objective: To clarify the effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) on the clinical outcomes of patients with coronary heart disease (CHD) complicated with reduced ejection fraction hear…
View article: The Influence of Industrial Role Positioning Strategy in Place Brand Internationalization on the Purchase Intention of Host Country Consumers from the Perspective of Moral Legitimacy
The Influence of Industrial Role Positioning Strategy in Place Brand Internationalization on the Purchase Intention of Host Country Consumers from the Perspective of Moral Legitimacy Open
The transnational place brands often have difficulty in gaining role identification from host country consumers due to trade barriers and regulatory differences.Based on a moral legitimacy perspective, this study proposes a research model …
View article: Rare event of NTRK3 rearrangement and amplification in esophageal squamous cell carcinoma
Rare event of NTRK3 rearrangement and amplification in esophageal squamous cell carcinoma Open
Background: TRK tyrosine kinase inhibitors (larotrectinib or entrectinib) can cause an unknown histological response in NTRK fusion-positive cancer patients,and it has been approved by the US Food and Drug Administration.The neurotrophic t…
View article: Monocyte to high-density lipoprotein cholesterol ratio as long-term prognostic marker in patients with coronary artery disease undergoing percutaneous coronary intervention
Monocyte to high-density lipoprotein cholesterol ratio as long-term prognostic marker in patients with coronary artery disease undergoing percutaneous coronary intervention Open
View article: Combining subsidence theory and slope stability analysis method for building damage assessment in mountainous mining subsidence regions
Combining subsidence theory and slope stability analysis method for building damage assessment in mountainous mining subsidence regions Open
Ground subsidence and surface cracks caused by coal mining are typical man-made geological hazards that can severely damage the ecological environment and buildings. In China, within the theme of sustained and stable development, accurate …
View article: Prognostic Impact on Type B Acute Aortic Dissection with Renal Insufficiency: A Single-Center Study
Prognostic Impact on Type B Acute Aortic Dissection with Renal Insufficiency: A Single-Center Study Open
Aims: The aim was to study the impact of renal insufficiency on type B acute aortic dissection (AAD), in terms of in-hospital mortality and long-term survival. Materials and Methods: A total of 241 consecutive patients with type B AAD from…
View article: Exome Sequencing in a Family Identifies RECQL5 Mutation Resulting in Early Myocardial Infarction
Exome Sequencing in a Family Identifies RECQL5 Mutation Resulting in Early Myocardial Infarction Open
Coronary artery disease (CAD) including myocardial infarction (MI) is the leading cause of death worldwide and is commonly caused by the interaction between genetic factors and environmental risks. Despite intensive efforts using linkage a…
View article: <i>Flotillin-2</i>Gene Is Associated with Coronary Artery Disease in Chinese Han Population
<i>Flotillin-2</i>Gene Is Associated with Coronary Artery Disease in Chinese Han Population Open
There was a strong association between polymorphisms of flotillin-2 gene and CAD in the Chinese Han population. Persons with the GG genotype of rs3816848 may have a higher risk of CAD. Moreover, the plasma levels of TC were significantly d…
View article: FrzA gene protects cardiomyocytes from H2O2-induced oxidative stress through restraining the Wnt/Frizzled pathway
FrzA gene protects cardiomyocytes from H2O2-induced oxidative stress through restraining the Wnt/Frizzled pathway Open
View article: Long noncoding RNA MALAT1 as a putative biomarker of lymph node metastasis: a meta-analysis.
Long noncoding RNA MALAT1 as a putative biomarker of lymph node metastasis: a meta-analysis. Open
Recent studies in cancer have demonstrated that cancerous tissues have a significantly higher MALAT1 level than in noncancerous tissues. Overexpression of MALAT1 is associated with susceptibility to lymph node metastasis. This meta-analysi…
View article: Inhibition of the NF-κB pathway by R65 ribozyme gene via adeno-associated virus serotype 9 ameliorated oxidized LDL induced human umbilical vein endothelial cell injury.
Inhibition of the NF-κB pathway by R65 ribozyme gene via adeno-associated virus serotype 9 ameliorated oxidized LDL induced human umbilical vein endothelial cell injury. Open
rAAV9-mediated R65 ribozyme gene transfection in cultured HUVECs effectively inhibits ox-LDL induced activation of NF-κB and production of inflammatory cytokines and prevents cell apoptosis.