Zhi He
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View article: Morphological Differences in Feeding and Digestive Organs, the Diversity of Intestinal Microorganisms, and Variations in Digestive Enzyme Activity Promote the Differentiation of Nutritional Niches in Schizothoracinae Species
Morphological Differences in Feeding and Digestive Organs, the Diversity of Intestinal Microorganisms, and Variations in Digestive Enzyme Activity Promote the Differentiation of Nutritional Niches in Schizothoracinae Species Open
The mechanisms of nutritional niche differentiation among sympatric Schizothoracinae fishes play an important role in their adaptive evolution and should be considered in conservation strategies. To date, there have been no reports about t…
View article: Correction: Yang et al. The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis. Int. J. Mol. Sci. 2023, 24, 6169
Correction: Yang et al. The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis. Int. J. Mol. Sci. 2023, 24, 6169 Open
In the original publication [...]
View article: Genomic-based revelation of genetic structure and adaptive characterization of Schizopygopsis malacanthus in the Jinsha River and Yalong River
Genomic-based revelation of genetic structure and adaptive characterization of Schizopygopsis malacanthus in the Jinsha River and Yalong River Open
View article: LB1182 Multi-ancestry genome-wide association meta-analysis identifies novel systemic sclerosis loci and elucidates cell-type specific regulatory mechanisms
LB1182 Multi-ancestry genome-wide association meta-analysis identifies novel systemic sclerosis loci and elucidates cell-type specific regulatory mechanisms Open
View article: Renewal Design of an Urban Heritage Park: The Case of King Yu’s Terrace Park
Renewal Design of an Urban Heritage Park: The Case of King Yu’s Terrace Park Open
With the increasing awareness of heritage city protection around the world, relevant laws and regulations are constantly improving, and the methods and approaches for protection are gradually enriching [1]. Heritage protection work has mad…
View article: Effect of Seminal Plasma on the Freezability of Boar Sperm
Effect of Seminal Plasma on the Freezability of Boar Sperm Open
Background: Seminal plasma is an important component of semen and has a significant effect on sperm function. However, the relationship between seminal plasma and sperm freezing capacity has not been fully studied. Purpose: Exploring metab…
View article: The whole chromosome-level genome provides resources and insights into the endangered fish Percocypris pingi evolution and conservation
The whole chromosome-level genome provides resources and insights into the endangered fish Percocypris pingi evolution and conservation Open
Our study provides a high-quality chromosome-anchored reference genome for P. pingi and provides sufficient information on the chromosomes, which will lead to valuable resources for genetic, genomic, and biological studies of P. pingi and …
View article: Possible involvement of Jun, Foxo1, Nobox in the regulation of smad2/3 transcription in the protogynous hermaphroditic ricefield eel (Monopterus albus)
Possible involvement of Jun, Foxo1, Nobox in the regulation of smad2/3 transcription in the protogynous hermaphroditic ricefield eel (Monopterus albus) Open
Small mothers against decapentaplegic2/3 (Smad2/3) are two signalling intermediates in the transforming growth factor beta (TGF-β) signalling pathway, which plays a critical role in gonad development. However, a systemic analysis of Smad2/…
View article: Smad4 and FoxH1 potentially interact to regulate cyp19a1a promoter in the ovary of ricefield eel (Monopterus albus)
Smad4 and FoxH1 potentially interact to regulate cyp19a1a promoter in the ovary of ricefield eel (Monopterus albus) Open
Background Cyp19a1a is a key enzyme in the pathway that converts androgens into estrogen and is regulated by TGF-β signaling. Smad4 and FoxH1 are downstream effectors of TGF-β signaling and may play important roles in ovarian development i…
View article: Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus)
Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus) Open
View article: Reduced representative methylome profiling of cell-free DNA for breast cancer detection
Reduced representative methylome profiling of cell-free DNA for breast cancer detection Open
Background Whole-genome methylation sequencing of cfDNA is not cost-effective for tumor detection. Here, we introduce reduced representative methylome profiling (RRMP), which employs restriction enzyme for depletion of AT-rich sequence to …
View article: Population structure and adaptability analysis of Schizothorax o’connori based on whole-genome resequencing
Population structure and adaptability analysis of Schizothorax o’connori based on whole-genome resequencing Open
Background Schizothorax o’connori is an endemic fish distributed in the upper and lower reaches of the Yarlung Zangbo River in China. It has experienced a fourth round of whole gene replication events and is a good model for exploring the …
View article: Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors
Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors Open
Introduction The utilization of large-scale claims databases has greatly improved the management, accessibility, and integration of extensive medical data. However, its potential for systematically identifying comorbidities in the context …
View article: Transcriptomic and metabolomic analyses reveal that lemon extract prolongs Drosophila lifespan by affecting metabolism
Transcriptomic and metabolomic analyses reveal that lemon extract prolongs Drosophila lifespan by affecting metabolism Open
Ageing is an evolutionarily conserved and irreversible biological process in different species. Numerous studies have reported that taking medicine is an effective approach to slow ageing. Lemon extract (LE) is a natural extract of lemon f…
View article: History cooling events caused migrations of endangered Cathaya argyrophylla into low latitude refuges
History cooling events caused migrations of endangered Cathaya argyrophylla into low latitude refuges Open
Cathaya argyrophylla, referred as “the giant panda of plants”, is an endangered relict conifer species endemic to subtropical mountainous in China. The remanent populations of C. argyrophylla only survive in four refuges, while how the spe…
View article: Regulatory mechanism of circular <scp>RNAs</scp> in neurodegenerative diseases
Regulatory mechanism of circular <span>RNAs</span> in neurodegenerative diseases Open
Background Neurodegenerative disease is a collective term for a category of diseases that are caused by neuronal dysfunction, such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). Circular RNA…
View article: FoxH1 Represses the Promoter Activity of cyp19a1a in the Ricefield Eel (Monopterus albus)
FoxH1 Represses the Promoter Activity of cyp19a1a in the Ricefield Eel (Monopterus albus) Open
Forkhead box H1 (FoxH1) is a sexually dimorphic gene in Oreochromis niloticus, Oplegnathus fasciatus, and Acanthopagrus latus, indicating that it is essential for gonadal development. In the present study, the molecular characteristics and…
View article: LncRNAs are involved in regulating ageing and age-related disease through the adenosine monophosphate-activated protein kinase signalling pathway
LncRNAs are involved in regulating ageing and age-related disease through the adenosine monophosphate-activated protein kinase signalling pathway Open
A long noncoding RNA (lncRNA) is longer than 200 bp. It regulates various biological processes mainly by interacting with DNA, RNA, or protein in multiple kinds of biological processes. Adenosine monophosphate-activated protein kinase (AMP…
View article: Comparative Population Dynamics of Schizothorax wangchiachii (Cyprinidae: Schizothoracinae) in the Middle Reaches of the Yalong River and the Upper Reaches of the Jinsha River, China
Comparative Population Dynamics of Schizothorax wangchiachii (Cyprinidae: Schizothoracinae) in the Middle Reaches of the Yalong River and the Upper Reaches of the Jinsha River, China Open
To explore the differences in the growth characteristics and population dynamics of Schizothorax wangchiachii populations in the Jinsha River (JSR) and the Yalong River (YLR), samples were collected in the upper reaches of the JSR (n = 230…
View article: Genetic Structure and Differentiation of Endangered Cycas Species Indicate a Southward Migration Associated with Historical Cooling Events
Genetic Structure and Differentiation of Endangered Cycas Species Indicate a Southward Migration Associated with Historical Cooling Events Open
Understanding the genetic structure and differentiation in endangered species is of significance in detecting their phylogenetic relationships and prioritizing conservation. Here we sampled five endangered Cycas species endemic to southwes…
View article: The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis
The Expression Pattern of tRNA-Derived Small RNAs in Adult Drosophila and the Function of tRF-Trp-CCA-014-H3C4 Network Analysis Open
tRNA-derived small RNAs (tsRNAs) are derived from tRNA and include tRNA halves (tiRNAs) and tRNA fragments (tRFs). tsRNAs have been implicated in a variety of important biological functions, such as cell growth, transcriptional regulation,…
View article: Macrophage Migration Inhibitory Factor in Psoroptes ovis: Molecular Characterization and Potential Role in Eosinophil Accumulation of Skin in Rabbit and Its Implication in the Host–Parasite Interaction
Macrophage Migration Inhibitory Factor in Psoroptes ovis: Molecular Characterization and Potential Role in Eosinophil Accumulation of Skin in Rabbit and Its Implication in the Host–Parasite Interaction Open
Psoroptes ovis, a common surface-living mite of domestic and wild animals worldwide, results in huge economic losses and serious welfare issues in the animal industry. P. ovis infestation rapidly causes massive eosinophil infiltration in s…
View article: Age-related ceRNA networks in adult Drosophila ageing
Age-related ceRNA networks in adult Drosophila ageing Open
As Drosophila is an extensively used genetic model system, understanding of its regulatory networks has great significance in revealing the genetic mechanisms of ageing and human diseases. Competing endogenous RNA (ceRNA)-mediated regulati…
View article: History cooling events contributed to the endangered status of Pseudotsuga brevifolia endemic to limestone habitats
History cooling events contributed to the endangered status of Pseudotsuga brevifolia endemic to limestone habitats Open
Pseudotsuga brevifolia (Pinaceae) is endemic to limestone habitats in southwest China, and its population size is small and suffers risks of extinction. To detect reasons in explaining the endangered status of P. brevifolia, we here genoty…
View article: Hepatocellular carcinoma detection via targeted enzymatic methyl sequencing of plasma cell-free DNA
Hepatocellular carcinoma detection via targeted enzymatic methyl sequencing of plasma cell-free DNA Open
View article: Transcriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii)
Transcriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii) Open
Background Maintaining osmotic equilibrium plays an important role in the survival of cold-water fishes. Heat stress has been proven to reduce the activity of Na + /K + -ATPase in the gill tissue, leading to destruction of the osmotic equi…
View article: Additional file 1 of Transcriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii)
Additional file 1 of Transcriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii) Open
Additional file 1: Fig.S1. Temperature control Day1 to 7: temperature acclimation; Day7 to 14: Reaching targeted temperature. Day15 to 27: Summer water temperature exposure. Fig. S2. DEGs analysis. (A, B) DEGs analyzed in 24℃-vs-20℃. (C, D…
View article: Expression Patterns and Gonadotropin Regulation of the TGF-β II Receptor (Bmpr2) during Ovarian Development in the Ricefield Eel Monopterus albus
Expression Patterns and Gonadotropin Regulation of the TGF-β II Receptor (Bmpr2) during Ovarian Development in the Ricefield Eel Monopterus albus Open
Bmpr2 plays a central role in the regulation of reproductive development in mammals, but its role during ovarian development in fish is still unclear. To ascertain the function of bmpr2 in ovarian development in the ricefield eel, we isola…
View article: Fish Community Structure and Biomass Particle-Size Spectrum in the Upper Reaches of the Jinsha River (China)
Fish Community Structure and Biomass Particle-Size Spectrum in the Upper Reaches of the Jinsha River (China) Open
To understand the characteristics of the fish community structure and biomass particle-size spectrum in the upper reaches of the Jinsha River, fish and environmental surveys were conducted in 21 segments of the upper reaches of the Jinsha …
View article: Complete Mitogenome of Oreolalax omeimontis Reveals Phylogenetic Status and Novel Gene Arrangement of Archaeobatrachia
Complete Mitogenome of Oreolalax omeimontis Reveals Phylogenetic Status and Novel Gene Arrangement of Archaeobatrachia Open
Species of the genus Oreolalax displayed crucial morphological characteristics of vertebrates transitioning from aquatic to terrestrial habitats; thus, they can be regarded as a representative vertebrate genus for this landing phenomenon. …