Ziyun Wan
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View article: A population-based study of precision health assessments using multi-omics network-derived biological functional modules
A population-based study of precision health assessments using multi-omics network-derived biological functional modules Open
View article: Genome-Wide Identification of Petunia HSF Genes and Potential Function of PhHSF19 in Benzenoid/Phenylpropanoid Biosynthesis
Genome-Wide Identification of Petunia HSF Genes and Potential Function of PhHSF19 in Benzenoid/Phenylpropanoid Biosynthesis Open
Volatile benzenoids/phenylpropanoids are the main flower scent compounds in petunia (Petunia hybrida). Heat shock factors (HSFs), well known as the main regulator of heat stress response, have been found to be involved in the biosynthesis …
View article: Distinct biological ages of organs and systems identified from a multi-omics study
Distinct biological ages of organs and systems identified from a multi-omics study Open
Biological age (BA) has been proposed to evaluate the aging status instead of chronological age (CA). Our study shows evidence that there might be multiple "clocks" within the whole-body system: systemic aging drivers/clocks overlaid with …
View article: Corrigendum: Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire
Corrigendum: Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire Open
[This corrects the article DOI: 10.3389/fimmu.2019.02064.].
View article: Developing an Unbiased Multiplex PCR System to Enrich the TRB Repertoire Toward Accurate Detection in Leukemia
Developing an Unbiased Multiplex PCR System to Enrich the TRB Repertoire Toward Accurate Detection in Leukemia Open
Accurate T cell receptor repertoire profiling has provided novel biological and clinical insights in widespread immunological settings; however, there is a lack of reference materials in the community that can be used to calibrate and opti…
View article: Single-cell RNA-seq unveils critical regulators of human FOXP3+ regulatory T cell stability
Single-cell RNA-seq unveils critical regulators of human FOXP3+ regulatory T cell stability Open
The heterogeneity and plasticity of T lymphocytes is critical for determining immune response outcomes. Functional regulatory T (Treg) cells are commonly characterized by stable FOXP3 expression and have reported to exhibit heterogeneous p…
View article: Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire
Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire Open
T cells recognize antigens as peptides bound to major histocompatibility complex (MHC) proteins through T cell receptors (TCRs) on their surface. To recognize a wide range of pathogens, each individual possesses a substantial number of TCR…
View article: Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood
Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood Open
Background For both pediatric and adult patients, umbilical cord blood (UCB) transplant is a therapeutic option for a variety of hematologic diseases, such as blood cancers, myeloproliferative disorders, genetic diseases, and metabolic dis…
View article: Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire
Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire Open
T cells recognize antigens as peptides bound to major histocompatibility complex (MHC) proteins through T cell receptors (TCRs) on their surface. To recognize a wide range of pathogens, each individual possesses a substantial number of TCR…
View article: Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood
Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood Open
Umbilical cord blood (UCB) transplant is a therapeutic option for both pediatric and adult patients with a variety of hematologic diseases such as several types of blood cancers, myeloproliferative disorders, genetic diseases, and metaboli…