Zoe E. Whiteman
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View article: Podoplanin expression identifies human airway basal cells with higher progenitor cell potential
Podoplanin expression identifies human airway basal cells with higher progenitor cell potential Open
Basal cells are key to maintaining and repairing a functioning airway epithelium. Understanding how basal cells maintain normal airways provides a foundation for interpreting their dysfunction in disease states and for the development of n…
View article: 187P Remodelling of MHC class II antigen presentation by malignant and premalignant epithelial cells during squamous lung carcinogenesis
187P Remodelling of MHC class II antigen presentation by malignant and premalignant epithelial cells during squamous lung carcinogenesis Open
View article: Aberrant basal cell clonal dynamics shape early lung carcinogenesis
Aberrant basal cell clonal dynamics shape early lung carcinogenesis Open
Preinvasive squamous lung lesions are precursors of lung squamous cell carcinoma (LUSC). The cellular events underlying lesion formation are unknown. Using a carcinogen-induced model of LUSC with no added genetic hits or cell type bias, we…
View article: 1032 Early remodelling of CD4 T cell differentiation in lung squamous carcinogenesis
1032 Early remodelling of CD4 T cell differentiation in lung squamous carcinogenesis Open
Background Advanced lung cancer kills 90% of patients within a decade, underscoring an urgent need for improved early detection and prevention technologies. T cell responses are initiated and dysregulated during early carcinogenesis in …
View article: Mapping lung squamous cell carcinoma pathogenesis through in vitro and in vivo models
Mapping lung squamous cell carcinoma pathogenesis through in vitro and in vivo models Open