Zonggao Shi
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View article: Fast and sensitive detection of targeted gene fusions using frequency minimizers and fuzzy pattern matching with Fuzzion2
Fast and sensitive detection of targeted gene fusions using frequency minimizers and fuzzy pattern matching with Fuzzion2 Open
To enable fast and sensitive fusion detection critical for clinical oncology testing, we developed Fuzzion2, a pattern-matching program for detecting targeted gene fusions that employs an index of frequency minimizers and fuzzy matching to…
View article: Novel <i>ACTB::FER</i> Promoter Swap Fusion Characterizes Rare Superficial Myoid/Myofibroblastic Tumors
Novel <i>ACTB::FER</i> Promoter Swap Fusion Characterizes Rare Superficial Myoid/Myofibroblastic Tumors Open
Pediatric fibroblastic, myofibroblastic, and myoid tumors encompass several entities, many with characteristic gene fusions that are now emerging as molecularly defined tumor groups. Here, we present two cases of spindle cell neoplasms wit…
View article: Comparison of Molecular Testing Methodologies for <i>CIC</i>-Rearranged Sarcomas
Comparison of Molecular Testing Methodologies for <i>CIC</i>-Rearranged Sarcomas Open
Context.— Molecular detection of a capicua transcriptional repressor (CIC) rearrangement is critical for diagnosing CIC-rearranged sarcoma (CIC-RS) but is analytically challenging. Objective.— To compare the technical performance of fluore…
View article: <i>MYH9::LTK</i> Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm
<i>MYH9::LTK</i> Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm Open
View article: Supplementary Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression
Supplementary Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression Open
Supplementary Data from Urinary-Type Plasminogen Activator Receptor/α3β1 Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression
View article: Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression
Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression Open
Oral squamous cell carcinoma (OSCC) has 50% 5-year survival rate, highlighting our limited understanding of the molecular events that contribute to disease progression. Microarray analyses of primary oral tumors have identified urinary-…
View article: Supplementary Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression
Supplementary Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression Open
Supplementary Data from Urinary-Type Plasminogen Activator Receptor/α3β1 Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression
View article: Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression
Data from Urinary-Type Plasminogen Activator Receptor/α<sub>3</sub>β<sub>1</sub> Integrin Signaling, Altered Gene Expression, and Oral Tumor Progression Open
Oral squamous cell carcinoma (OSCC) has 50% 5-year survival rate, highlighting our limited understanding of the molecular events that contribute to disease progression. Microarray analyses of primary oral tumors have identified urinary-…
View article: Supplemental Figure S4 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S4 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Immunohistochemical analysis of proliferation in murine tumor tissues.
View article: Supplemental Figure S2 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S2 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Representative histology of Cohort 2 metastatic implants in control or DIO C57/Bl6 mice.
View article: Supplemental Figure Legends from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure Legends from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Legends for Supplemental Figures S1-S4
View article: Data from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Data from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic malignancy, with high mortality attributable to widespread intraperitoneal metastases. Recent meta-analyses report an association between obesity, ovarian cance…
View article: Data from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Data from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic malignancy, with high mortality attributable to widespread intraperitoneal metastases. Recent meta-analyses report an association between obesity, ovarian cance…
View article: Supplemental Figure S1 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S1 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Overview of experimental cohorts.
View article: Supplemental Figure S3 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S3 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Representative histology of Cohort 3 metastatic implants in wild type control or ob/ob mice.
View article: Supplemental Figure S3 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S3 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Representative histology of Cohort 3 metastatic implants in wild type control or ob/ob mice.
View article: Supplemental Figure Legends from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure Legends from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Legends for Supplemental Figures S1-S4
View article: Supplemental Figure S2 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S2 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Representative histology of Cohort 2 metastatic implants in control or DIO C57/Bl6 mice.
View article: Supplemental Figure S4 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S4 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Immunohistochemical analysis of proliferation in murine tumor tissues.
View article: Supplemental Figure S1 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Supplemental Figure S1 from Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Overview of experimental cohorts.
View article: Progressive metastatic infantile fibrosarcoma with multiple acquired mutations
Progressive metastatic infantile fibrosarcoma with multiple acquired mutations Open
Infantile fibrosarcoma is the most common soft-tissue sarcoma in children under the age of 1 yr and is defined molecularly by NTRK fusion proteins. This tumor is known to be locally invasive; however, although rare, metastases can occur. T…
View article: In vivo selection of highly metastatic human ovarian cancer sublines reveals role for AMIGO2 in intra-peritoneal metastatic regulation
In vivo selection of highly metastatic human ovarian cancer sublines reveals role for AMIGO2 in intra-peritoneal metastatic regulation Open
View article: Aging Increases Susceptibility to Ovarian Cancer Metastasis in Murine Allograft Models and Alters Immune Composition of Peritoneal Adipose Tissue
Aging Increases Susceptibility to Ovarian Cancer Metastasis in Murine Allograft Models and Alters Immune Composition of Peritoneal Adipose Tissue Open
View article: RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer
RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer Open
We performed RNA-seq on an Illumina platform for 7 patients with endometrioid endometrial carcinoma for which both tumor tissue and adjacent noncancer tissue were available. A total of 66 genes were differentially expressed with significan…
View article: Tumor infiltrating leukocyte density is independent of tumor grade and molecular subtype in aggressive breast cancer of Western Kenya
Tumor infiltrating leukocyte density is independent of tumor grade and molecular subtype in aggressive breast cancer of Western Kenya Open
View article: Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration
Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration Open
View article: Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration
Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration Open
Background Breast cancer incidence and mortality vary significantly among different nations and racial groups. African nations have the highest breast cancer mortality rates in the world, even though the incidence rates are below those of …
View article: Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages
Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages Open
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic malignancy, with high mortality attributable to widespread intraperitoneal metastases. Recent meta-analyses report an association between obesity, ovarian cance…
View article: Decrease of miR-146a is associated with the aggressiveness of human oral squamous cell carcinoma
Decrease of miR-146a is associated with the aggressiveness of human oral squamous cell carcinoma Open
View article: Table of Contents
Table of Contents Open