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View article: Subclinical myocardial changes in rheumatoid arthritis: cardiovascular magnetic resonance evidence of immuno-inflammatory remodeling
Subclinical myocardial changes in rheumatoid arthritis: cardiovascular magnetic resonance evidence of immuno-inflammatory remodeling Open
Objectives Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) risk, yet the mechanisms remain unclear. This study aimed to evaluate myocardial structure, function, and tissue characterization using cardiovascular ma…
View article: Health Status Outcomes After Computed Tomography or Invasive Coronary Angiography for Stable Chest Pain
Health Status Outcomes After Computed Tomography or Invasive Coronary Angiography for Stable Chest Pain Open
Importance The effect of computed tomography (CT) vs invasive coronary angiography (ICA) on health status outcomes is unknown. Objective To evaluate CT and ICA first-test strategies on quality of life (QOL) and angina. Design, Setting, and…
View article: Atorvastatin and Myocardial Extracellular Volume Expansion During Anthracycline-Based Chemotherapy
Atorvastatin and Myocardial Extracellular Volume Expansion During Anthracycline-Based Chemotherapy Open
Compared with placebo, atorvastatin limited ECV expansion among participants with lymphoma undergoing anthracycline chemotherapy. This study is the first to provide mechanistic insight into statins' cardioprotective effects with anthracycl…
View article: Atorvastatin and left ventricular global circumferential strain during anthracycline-based chemotherapy
Atorvastatin and left ventricular global circumferential strain during anthracycline-based chemotherapy Open
View article: Atorvastatin and left atrial function during anthracycline-based chemotherapy
Atorvastatin and left atrial function during anthracycline-based chemotherapy Open
NCT02943590; https://clinicaltrials.gov/study/NCT02943590.
View article: Modeling the Impact of Extracellular Vesicle Cargoes in the Diagnosis of Coronary Artery Disease
Modeling the Impact of Extracellular Vesicle Cargoes in the Diagnosis of Coronary Artery Disease Open
Objectives: We aimed to assess the relationship among circulating extracellular vesicles (EVs), hypoxia-related proteins, and the conventional risk factors of life-threatening coronary artery disease (CAD) to find more precise novel biomar…
View article: Modelling the Impact of Extracellular Vesicle Cargoes in the Diagnosis of Coronary Artery Disease
Modelling the Impact of Extracellular Vesicle Cargoes in the Diagnosis of Coronary Artery Disease Open
Objectives: We aimed to assess the relationship between circulating extracellular vesicles (EVs), hypoxia-related proteins and conventional risk factors of the life threatening coro-nary artery disease (CAD) to find more precise novel biom…
View article: Molecular fingerprints of cardiovascular toxicities of immune checkpoint inhibitors
Molecular fingerprints of cardiovascular toxicities of immune checkpoint inhibitors Open
View article: Prior cardiac ischemic injury exacerbates immune checkpoint inhibitor-induced cardiotoxicity
Prior cardiac ischemic injury exacerbates immune checkpoint inhibitor-induced cardiotoxicity Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Momentum grant of the Hungarian Academy of Sciences Introduction Immune checkpoint inhibitors (ICI), such as monoclonal antib…
View article: Evaluating the predictive value of late gadolinium enhancement assessed by cardiac magnetic resonance on sudden cardiac death in patients selected for implantable cardioverter defibrillator and cardiac resynchronization therapy implantation: a systematic review and meta-analysis
Evaluating the predictive value of late gadolinium enhancement assessed by cardiac magnetic resonance on sudden cardiac death in patients selected for implantable cardioverter defibrillator and cardiac resynchronization therapy implantation: a systematic review and meta-analysis Open
Aims Late gadolinium enhancement (LGE) assessed by cardiovascular magnetic resonance (CMR) can evaluate myocardial scar associated with a higher risk of sudden cardiac death (SCD), which can guide the selection between cardiac resynchroniz…
View article: One-Day Interruption of NOAC Is Associated with Low Risk of Periprocedural Adverse Events during Pulmonary Vein Isolation If Combined with Left Atrial Thrombus Exclusion with Computed Tomography
One-Day Interruption of NOAC Is Associated with Low Risk of Periprocedural Adverse Events during Pulmonary Vein Isolation If Combined with Left Atrial Thrombus Exclusion with Computed Tomography Open
Background: Safety, efficacy, and patient comfort are the expectations during pulmonary vein isolation (PVI). We aimed to validate the combined advantages of pre- and periprocedural anticoagulation with non-vitamin K anticoagulants (NOACs)…
View article: The evolution of defining and the reinterpretation of cardiotoxicity
The evolution of defining and the reinterpretation of cardiotoxicity Open
SAŽETAK: Jedno od vodećih načela kardioonkološke prakse jest minimiziranje nepotrebnog prekidanja antitumorskog liječenja
View article: Seroconversion after SARS‐CoV‐2 vaccination is protective against severe COVID‐19 disease in heart transplant recipients
Seroconversion after SARS‐CoV‐2 vaccination is protective against severe COVID‐19 disease in heart transplant recipients Open
Background Heart transplant (HTX) recipients are prone to develop complications after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. Vaccination is often ineffective due to weaker immunogenicity. In this high‐volum…
View article: Atrial and ventricular arrhythmias with immune checkpoint inhibitor therapy in patients without evidence of myocarditis
Atrial and ventricular arrhythmias with immune checkpoint inhibitor therapy in patients without evidence of myocarditis Open
Background Immune checkpoint inhibitor (ICI) therapy has improved the prognosis of many cancer types. Immune-related adverse events (irAEs) are common and recent studies suggest ICI therapy may be associated with an increased risk of arrhy…
View article: Feasibility and image quality of bright-blood and black-blood phase-sensitive inversion recovery (BOOST) sequence in clinical practice using for left atrial visualization in patients with atrial fibrillation
Feasibility and image quality of bright-blood and black-blood phase-sensitive inversion recovery (BOOST) sequence in clinical practice using for left atrial visualization in patients with atrial fibrillation Open
View article: Atorvastatin for Anthracycline-Associated Cardiac Dysfunction
Atorvastatin for Anthracycline-Associated Cardiac Dysfunction Open
Importance Anthracyclines treat a broad range of cancers. Basic and retrospective clinical data have suggested that use of atorvastatin may be associated with a reduction in cardiac dysfunction due to anthracycline use. Objective To test w…
View article: Impact of immune checkpoint inhibitors on atherosclerosis progression in patients with lung cancer
Impact of immune checkpoint inhibitors on atherosclerosis progression in patients with lung cancer Open
Background Patients with lung cancer face a heightened risk of atherosclerosis-related cardiovascular events. Despite the strong scientific rationale, there is currently a lack of clinical evidence examining the impact of immune checkpoint…
View article: Coronary CT-based FFR in patients with acute myocardial infarction might predict follow-up invasive FFR: The XPECT-MI study
Coronary CT-based FFR in patients with acute myocardial infarction might predict follow-up invasive FFR: The XPECT-MI study Open
View article: One day interruption of NOAC is associated with low risk of periprocedural adverse events during pulmonary vein isolation if combined with left atrial thrombus exclusion with computed tomography
One day interruption of NOAC is associated with low risk of periprocedural adverse events during pulmonary vein isolation if combined with left atrial thrombus exclusion with computed tomography Open
Purpose: Safety, efficacy, and patient comfort are the primary expectations during pulmonary vein isolation (PVI). We aimed to validate the combined advantages of pre-and periprocedural anticoagulation with non-vitamin K anticoagulants (NO…
View article: A kardiotoxicitás definíciójának evolúciója és újraértelmezése
A kardiotoxicitás definíciójának evolúciója és újraértelmezése Open
Az onko-kardiológiai gyakorlat egyik vezérelve a daganatellenes terápia szükségtelen megszakításának minimalizálása. A szakterület átfogó célja, hogy a daganatos betegek a lehető legjobb daganatellenes kezelésben részesüljenek, egyúttal mi…
View article: Az immunellenőrzőpont-gátló onkológiai terápiák kardiovaszkuláris mellékhatásai
Az immunellenőrzőpont-gátló onkológiai terápiák kardiovaszkuláris mellékhatásai Open
Az elmúlt 30 évben jelentős előrelépés történt a daganatellenes terápiákban. Az immunterápiák bevezetése számottevően javította az onkológiai betegek túlélését. Az immunellenőrzőpont-gátlók (ICI) az immunterápiáknak leggyakrabban alkalmazo…
View article: A prosztatarák kezelésének kardiológiai vontakozása
A prosztatarák kezelésének kardiológiai vontakozása Open
A prosztatarák (PC) kezelésében az elmúlt években számos új terápiás készítményt hagytak jóvá, jelentősen javítva a betegek életminőségét és túlélését. Jelenleg a PC szisztémás kezelése hormonterápiából, kemoterápiából, immunterápiá- ból, …
View article: Cardiac strain is lower among women with HIV in relation to monocyte activation
Cardiac strain is lower among women with HIV in relation to monocyte activation Open
Background Women with HIV (WWH) face heightened risks of heart failure; however, insights on immune/inflammatory pathways potentially contributing to left ventricular (LV) systolic dysfunction among WWH remain limited. Setting Massachusett…
View article: Pre-Existing Autoimmune Disease Increases the Risk of Cardiovascular and Noncardiovascular Events After Immunotherapy
Pre-Existing Autoimmune Disease Increases the Risk of Cardiovascular and Noncardiovascular Events After Immunotherapy Open
View article: Characterization of immune checkpoint inhibitor‐induced cardiotoxicity reveals interleukin‐17A as a driver of cardiac dysfunction after anti‐PD‐1 treatment
Characterization of immune checkpoint inhibitor‐induced cardiotoxicity reveals interleukin‐17A as a driver of cardiac dysfunction after anti‐PD‐1 treatment Open
Background and Purpose Immune checkpoint inhibitors (ICI), such as anti‐PD‐1 monoclonal antibodies, have revolutionized cancer therapy by enhancing the cytotoxic effects of T‐cells against tumours. However, enhanced T‐cell activity also ma…
View article: Certainties and Uncertainties of Cardiac Magnetic Resonance Imaging in Athletes
Certainties and Uncertainties of Cardiac Magnetic Resonance Imaging in Athletes Open
Prolonged and intensive exercise induces remodeling of all four cardiac chambers, a physiological process which is coined as the “athlete’s heart”. This cardiac adaptation, however, shows overlapping features with non-ischemic cardiomyopat…
View article: Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial
Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial Open
Objective To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women and men with stable chest pain suspected to be caused by coronary artery disease. Design Prospective, multicentre, randomis…
View article: Global Circumferential and Radial Strain Among Patients With Immune Checkpoint Inhibitor Myocarditis
Global Circumferential and Radial Strain Among Patients With Immune Checkpoint Inhibitor Myocarditis Open
View article: Sodium-Glucose Co-Transporter-2 Inhibitors and Cardiac Outcomes Among Patients Treated With Anthracyclines
Sodium-Glucose Co-Transporter-2 Inhibitors and Cardiac Outcomes Among Patients Treated With Anthracyclines Open
View article: The efficacy and safety of cardio-protective therapy in patients with 5-FU (Fluorouracil)-associated coronary vasospasm
The efficacy and safety of cardio-protective therapy in patients with 5-FU (Fluorouracil)-associated coronary vasospasm Open
Background Coronary vasospasm is a known side effect of 5-FU (fluorouracil) therapy. Beyond switching to non-5FU-based chemotherapy, there are no established treatments for 5-FU associated coronary vasospam. Our objective was to assess the…