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View article: Myocardial expression of immune checkpoint molecules in patients with advanced heart failure
Myocardial expression of immune checkpoint molecules in patients with advanced heart failure Open
Introduction Immune checkpoints (ICs) are key regulatory molecules of the adaptive immune response. Immune checkpoint inhibition (ICI) is a novel, revolutionary strategy for the treatment of many cancer types. However, ICIs can lead to var…
View article: Prior cardiac ischemic injury exacerbates immune checkpoint inhibitor-induced cardiotoxicity
Prior cardiac ischemic injury exacerbates immune checkpoint inhibitor-induced cardiotoxicity Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Momentum grant of the Hungarian Academy of Sciences Introduction Immune checkpoint inhibitors (ICI), such as monoclonal antib…
View article: Rictor is a central target of the molecular network of cardiac ProtectomiRs
Rictor is a central target of the molecular network of cardiac ProtectomiRs Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): National Research, Development and Innovation Office of Hungary (NKFIA; NVKP-16-1-2016-0017 National Heart Program and OTKA-F…
View article: Responsiveness of the widely used cardiomyocyte cell platforms to simulated ischemia/reperfusion
Responsiveness of the widely used cardiomyocyte cell platforms to simulated ischemia/reperfusion Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): National Research, Development and Innovation Office of Hungary (NKFIA; NVKP-16-1-2016-0017 National Heart Program and OTKA-F…
View article: Immune checkpoint inhibition with PD-1 inhibitor induces cardiac dysfunction without overt myocarditis in C57BL/6J mice
Immune checkpoint inhibition with PD-1 inhibitor induces cardiac dysfunction without overt myocarditis in C57BL/6J mice Open
Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): European Union’s Horizon 2020 Research and Innovation Programme under grant agreement no. 739593 “Semmelweis 250+ Kiválósági PhD Ösztön…
View article: Transcriptomic analysis and comparative characterization of rat H9C2, human AC16 and murine HL-1 cardiac cell lines
Transcriptomic analysis and comparative characterization of rat H9C2, human AC16 and murine HL-1 cardiac cell lines Open
Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): European Union's Horizon 2020 research and innovation programme National Research, Development and Innovation Fund of Hungary Backgroun…
View article: Investigation of cardiotoxicity by dipeptidyl-peptidase-4 inhibitors in a human cardiomyocyte cell line as well as in samples from chronic heart failure patients
Investigation of cardiotoxicity by dipeptidyl-peptidase-4 inhibitors in a human cardiomyocyte cell line as well as in samples from chronic heart failure patients Open
Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): Horizon 2020 research and innovation programme, Ministry for Innovation and Technology Background Dipeptidyl-peptidase-4 (DPP4) inhibit…
View article: Cardiovascular Glycobiology11Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning12Deregulation of thioredoxin system contributes to monocyte dysfunction in diabetes mellitus: Implications for impaired arteriogenesis in type2 diabetic patients13High glucose increases gamma-glutamyltransferase-induced tissue factor expression in human peripheral blood mononuclear cells
Cardiovascular Glycobiology11Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning12Deregulation of thioredoxin system contributes to monocyte dysfunction in diabetes mellitus: Implications for impaired arteriogenesis in type2 diabetic patients13High glucose increases gamma-glutamyltransferase-induced tissue factor expression in human peripheral blood mononuclear cells Open
BACKGROUND: A close association connects Gamma-GlutamylTransferase (GGT) activity to acute thrombotic events that coexisting diabetes increases exponentially. Tissue Factor (TF), the leading factor of acute thrombotic complications, is als…