Zhengxiang Wang
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View article: Potential Distribution Modeling and Conservation Gap Identification for Rare and Endangered Plant Species: A Case Study of 10 Species in Hubei Province
Potential Distribution Modeling and Conservation Gap Identification for Rare and Endangered Plant Species: A Case Study of 10 Species in Hubei Province Open
With the continuous increase in the demand for land and natural resources, driven by population growth and economic expansion, the conservation of rare and endangered species faces mounting pressure. Exploring how to achieve the target of …
View article: Metabolic Engineering of Bacillus licheniformis for High-Yield L-Lactic Acid and Galactooligosaccharide Retention in Complementary Synbiotics Production
Metabolic Engineering of Bacillus licheniformis for High-Yield L-Lactic Acid and Galactooligosaccharide Retention in Complementary Synbiotics Production Open
Using Bacillus licheniformis H107 as the initial strain, a novel complementary synbiotics production method was developed through comprehensive metabolic engineering strategies. Key modifications included the systematic analysis and recons…
View article: Protection against post-resuscitation renal injury by Artesunate via inhibition of caspase-3/Gasdermin E -mediated pyroptosis
Protection against post-resuscitation renal injury by Artesunate via inhibition of caspase-3/Gasdermin E -mediated pyroptosis Open
Background: Post-resuscitation renal injury is the common complication after cardiac arrest and resuscitation. Artesunate (Art) has been confirmed to protect against regional ischemia–reperfusion injuries in multiple organs. This study aim…
View article: Decoupling sucrose utilization from oxygen-responsive regulation for high-efficiency L-lactic acid production in Escherichia coli
Decoupling sucrose utilization from oxygen-responsive regulation for high-efficiency L-lactic acid production in Escherichia coli Open
The shift toward sustainable biomanufacturing necessitates microbial platforms that efficiently convert low-cost, non-food feedstocks into high-value chemicals. Sucrose, a widely available and economical carbon source, remains underutilize…
View article: LVLMs are Bad at Overhearing Human Referential Communication
LVLMs are Bad at Overhearing Human Referential Communication Open
During spontaneous conversations, speakers collaborate on novel referring expressions, which they can then re-use in subsequent conversations. Understanding such referring expressions is an important ability for an embodied agent, so that …
View article: Biodegradation mechanism of cellulose, hemicellulose, and lignin in bacteria-dominant aerobic composting from agricultural biomass waste:A review
Biodegradation mechanism of cellulose, hemicellulose, and lignin in bacteria-dominant aerobic composting from agricultural biomass waste:A review Open
The conversion of abundantly produced agricultural waste has been the bottleneck and research hotspot in the development of the agricultural economy. Composting has been a sustainable treatment method for agricultural-sourced waste, in whi…
View article: Synergistic Engineering of the Twin-Arginine Translocation (Tat) Pathway and Membrane Capacity Enhances Extracellular Production of Amylosucrase in Bacillus licheniformis
Synergistic Engineering of the Twin-Arginine Translocation (Tat) Pathway and Membrane Capacity Enhances Extracellular Production of Amylosucrase in Bacillus licheniformis Open
Amylosucrase (AS) is a highly versatile enzyme with significant potential for industrial applications, including functional food production and glycosylation of bioactive compounds. However, its large-scale production is hampered by low se…
View article: Nucleophosmin 1 inhibits the replication of influenza A virus by competitively binding viral RNA with viral proteins
Nucleophosmin 1 inhibits the replication of influenza A virus by competitively binding viral RNA with viral proteins Open
Influenza A viruses (IAVs) are single-stranded negative-sense RNA viruses that continually challenge animal and human health. In IAV-infected cells, host RNA-binding proteins play key roles in the life cycle of IAV by directly binding to v…
View article: Enhancing β-Galactosidase Performance for Galactooligosaccharides Preparation via Strategic Glucose Re-Tunneling
Enhancing β-Galactosidase Performance for Galactooligosaccharides Preparation via Strategic Glucose Re-Tunneling Open
This study focuses on the characterization and re-engineering of glucose transport in β-galactosidase (BglD) to enhance its catalytic efficiency. Computational prediction methods were employed to identify key residues constituting access t…
View article: Boosting Fructosyl Transferase’s Thermostability and Catalytic Performance for Highly Efficient Fructooligosaccharides (FOS) Production
Boosting Fructosyl Transferase’s Thermostability and Catalytic Performance for Highly Efficient Fructooligosaccharides (FOS) Production Open
Achieving enzymatic food processing at high substrate concentrations can significantly enhance production efficiency; however, related studies are notably insufficient. This study focused on the enzymatic synthesis of fructooligosaccharide…
View article: Acute waterborne cadmium exposure induces liver ferroptosis in Channa argus
Acute waterborne cadmium exposure induces liver ferroptosis in Channa argus Open
The impact of cadmium (Cd) toxicity on fish liver injury has received much attention in recent years. Currently, autophagy, apoptosis and endoplasmic reticulum stress were reported in Cd exposed fish liver, and if there are other mechanism…
View article: Evaluating LLMs with Multiple Problems at once
Evaluating LLMs with Multiple Problems at once Open
This paper shows the benefits and fruitfulness of evaluating LLMs with multiple problems at once, a paradigm we call multi-problem evaluation (MPE). Unlike conventional single-problem evaluation, where a prompt presents a single problem an…
View article: Long-Term Analysis of Spatial–Temporal Variation in Ecological Space Quality within Urban Agglomeration in the Middle Reaches of the Yangtze River
Long-Term Analysis of Spatial–Temporal Variation in Ecological Space Quality within Urban Agglomeration in the Middle Reaches of the Yangtze River Open
The assessment of ecological space quality (ESQ) and its spatio-temporal change monitoring are crucial for regional ecological management and sustainable development. However, there are few studies on how to construct a comprehensive ESQ a…
View article: FedKG: A Knowledge Distillation-Based Federated Graph Method for Social Bot Detection
FedKG: A Knowledge Distillation-Based Federated Graph Method for Social Bot Detection Open
Malicious social bots pose a serious threat to social network security by spreading false information and guiding bad opinions in social networks. The singularity and scarcity of single organization data and the high cost of labeling socia…
View article: Organic Electronics in Flexible Devices: Engineering Strategy, Synthesis, And Application
Organic Electronics in Flexible Devices: Engineering Strategy, Synthesis, And Application Open
In recent years, flexible electronics have made significant strides, especially in organic light-emitting diodes, photovoltaics, thin-film transistors, integrated circuits, sensors, and memories. This study investigates the pivotal role of…
View article: Evolution of H6N6 viruses in China between 2014 and 2019 involves multiple reassortment events
Evolution of H6N6 viruses in China between 2014 and 2019 involves multiple reassortment events Open
H6N6 avian influenza viruses (AIVs) have been widely detected in wild birds, poultry, and even mammals. Recently, H6N6 viruses were reported to be involved in the generation of H5 and H7 subtype viruses. To investigate the emergence, evolu…
View article: Tetrazolium viability test method for micro-seeds of the endangered plant<i> Deinanthe caerulea</i>
Tetrazolium viability test method for micro-seeds of the endangered plant<i> Deinanthe caerulea</i> Open
Deinanthe caerulea is a rare perennial herb endemic to China that has high medicinal and ornamental value. Seeds of D. caerulea are tiny with a thousand seed weight of only 200 mg. Thus, classical germination tests are difficult to apply i…
View article: Clustering Document Parts: Detecting and Characterizing Influence Campaigns from Documents
Clustering Document Parts: Detecting and Characterizing Influence Campaigns from Documents Open
We propose a novel clustering pipeline to detect and characterize influence campaigns from documents. This approach clusters parts of document, detects clusters that likely reflect an influence campaign, and then identifies documents linke…
View article: Novel enzyme-fermentation process for bioconversion of restaurant food waste into isomaltooligosaccharide-and L-lactic acid-enriched animal feed
Novel enzyme-fermentation process for bioconversion of restaurant food waste into isomaltooligosaccharide-and L-lactic acid-enriched animal feed Open
Introduction Considering the valuable organic fraction contained, restaurant food waste (RFW) has attracted more attention as an alternative substrate for animal feed production. In this work, a new enzyme-fermentation process (EFP) for di…
View article: METTL16 Promotes Stability of SYNPO2L mRNA and leading to Cancer Cell Lung Metastasis by Secretion of COL10A1 and attract the Cancer-Associated Fibroblasts
METTL16 Promotes Stability of SYNPO2L mRNA and leading to Cancer Cell Lung Metastasis by Secretion of COL10A1 and attract the Cancer-Associated Fibroblasts Open
The occurrence of metastasis is a major factor contributing to poor prognosis in colorectal cancer. Different stages of the disease play a crucial role in distant metastasis. Furthermore, m6A has been demonstrated to play a significant rol…
View article: Secretory expression of amylosucrase in <i>Bacillus licheniformis</i> through twin-arginine translocation pathway
Secretory expression of amylosucrase in <i>Bacillus licheniformis</i> through twin-arginine translocation pathway Open
Amylosucrase (EC 2.4.1.4) is a versatile enzyme with significant potential in biotechnology and food production. To facilitate its efficient preparation, a novel expression strategy was implemented in Bacillus licheniformis for the secreto…
View article: Probabilistic Linguistic Knowledge and Token-level Text Augmentation
Probabilistic Linguistic Knowledge and Token-level Text Augmentation Open
This paper investigates the effectiveness of token-level text augmentation and the role of probabilistic linguistic knowledge within a linguistically-motivated evaluation context. Two text augmentation programs, REDA and REDA$_{NG}$, were …