Zhen‐Yu Chen
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View article: Adsorption Performance and Mechanisms of Copper by Soil Glycoprotein-Modified Straw Biochar
Adsorption Performance and Mechanisms of Copper by Soil Glycoprotein-Modified Straw Biochar Open
Biochar is one of the most promising crop straw utilization pathways. However, its capacity for adsorbing heavy metals is limited, and there is a potential risk of secondary pollution, highlighting the importance of developing efficient an…
View article: Effectiveness and Safety of a Polyvinyl Alcohol Microsphere and Hyaluronic Acid Suspension for Chin Augmentation: A Randomized Controlled Trial and Multidisciplinary Study
Effectiveness and Safety of a Polyvinyl Alcohol Microsphere and Hyaluronic Acid Suspension for Chin Augmentation: A Randomized Controlled Trial and Multidisciplinary Study Open
Background Dermal fillers are a primary treatment for chin retrusion. However, current options have limitations in longevity and biomechanical properties. Objectives The aim of this study was to evaluate the efficacy and safety of a novel …
View article: The IL-33/ST2 Axis Promotes Traumatic Heterotopic Ossification by Driving Macrophage and Mast Cell-Mediated Inflammation via Autophagy Defects
The IL-33/ST2 Axis Promotes Traumatic Heterotopic Ossification by Driving Macrophage and Mast Cell-Mediated Inflammation via Autophagy Defects Open
Trauma-induced Heterotopic ossification (tHO) is the abnormal osteogenesis occurring in soft tissues after traumatic musculoskeletal injury, which can lead to severe limb movement impairment or even disability. Recent studies have indicate…
View article: LXR agonist rescues synaptic dysfunction and degeneration in SPG3A patient-specific iPSC-derived neurons
LXR agonist rescues synaptic dysfunction and degeneration in SPG3A patient-specific iPSC-derived neurons Open
Hereditary spastic paraplegias (HSPs) comprise a large, heterogeneous group of inherited disorders characterized by length-dependent axonal degeneration of corticospinal motor neurons, leading to lower extremity spasticity and gait impairm…
View article: Presentation of multiple endocrine neoplasia type 2A-associated ectopic cushing’s syndrome: case report and a systematic review
Presentation of multiple endocrine neoplasia type 2A-associated ectopic cushing’s syndrome: case report and a systematic review Open
Background Multiple endocrine neoplasia type 2 (MEN 2)-related ectopic Cushing’s syndrome (ECS) continues to present a clinical challenge due to its rarity and complexity. This study combines case analysis with a systematic literature revi…
View article: Small peptide P110 mitigates axonal degeneration of SPG15 patient iPSC-derived neurons by targeting mitochondrial dysfunction
Small peptide P110 mitigates axonal degeneration of SPG15 patient iPSC-derived neurons by targeting mitochondrial dysfunction Open
Hereditary Spastic Paraplegias (HSPs) are a group of heterogeneous neurological diseases characterized by axonal degeneration of corticospinal motor neurons. SPG15, a common autosomal recessive form of HSP, is caused by mutations in the ZF…
View article: Large language models as AI agents for digital atoms and molecules: Catalyzing a new era in computational biophysics
Large language models as AI agents for digital atoms and molecules: Catalyzing a new era in computational biophysics Open
In computational biophysics, where molecular data is expanding rapidly and system complexity is increasing exponentially, large language models (LLMs) and agent-based systems are fundamentally reshaping the field. This perspective article …
View article: Advances in mesenchymal stem cell-based therapies for recurrent spontaneous abortion
Advances in mesenchymal stem cell-based therapies for recurrent spontaneous abortion Open
Young women’s physical and mental health is seriously impacted by recurrent spontaneous abortion (RSA), a prevalent obstetric complication that is becoming more commonplace worldwide. Therefore, a thorough investigation into the pathophysi…
View article: UniUGG: Unified 3D Understanding and Generation via Geometric-Semantic Encoding
UniUGG: Unified 3D Understanding and Generation via Geometric-Semantic Encoding Open
Despite the impressive progress on understanding and generating images shown by the recent unified architectures, the integration of 3D tasks remains challenging and largely unexplored. In this paper, we introduce UniUGG, the first unified…
View article: Development and validation of an explainable machine learning model for predicting prognosis in sepsis patients with a history of cancer who were admitted to the intensive care unit
Development and validation of an explainable machine learning model for predicting prognosis in sepsis patients with a history of cancer who were admitted to the intensive care unit Open
Background Sepsis is the leading cause of mortality in critically ill cancer patients; however, traditional prognostic models fail to capture the complexity of their immune and physiological interactions. Methods This retrospective study a…
View article: Integrated flexible composite for robotic skin applications with sensing, EMI shielding, and flame/explosion resistance
Integrated flexible composite for robotic skin applications with sensing, EMI shielding, and flame/explosion resistance Open
In this study, a multifunctional composite membrane is developed for advanced robotic skin applications, combining strain sensing, EMI shielding, and flame/explosion resistance. The membrane is fabricated by coating copper onto woven polye…
View article: Geochemical Characteristics of Muscovite and Feldspars in Pegmatites: Significance for Rare Metal Pegmatite Mineralization in the Duanfengshan Area, Hubei Province, South China
Geochemical Characteristics of Muscovite and Feldspars in Pegmatites: Significance for Rare Metal Pegmatite Mineralization in the Duanfengshan Area, Hubei Province, South China Open
The Duanfengshan deposit is a newly discovered large pegmatitic‐type Nb‐Ta deposit in the central section of the Jiangnan orogenic belt, South China. There are three types of pegmatite in the Duanfengshan area: microcline pegmatite, microc…
View article: Effect of Water Deficit Stress on the Growth and Photosynthetic Characteristics of Okra Plant
Effect of Water Deficit Stress on the Growth and Photosynthetic Characteristics of Okra Plant Open
Water deficit stress significantly impacts the yield and quality of okra, an important edible and medicinal vegetable. Understanding the physiological adaptation mechanisms of okra under drought conditions and identifying effective adaptat…
View article: Physicochemical Characterization and Oral Bioavailability of Curcumin–Phospholipid Complex Nanosuspensions Prepared Based on Microfluidic System
Physicochemical Characterization and Oral Bioavailability of Curcumin–Phospholipid Complex Nanosuspensions Prepared Based on Microfluidic System Open
Background: Curcumin has been proved to have promising prospects in the fields of anti-inflammation, antibacterial, anti-oxidation, and neuroprotection. However, its poor water solubility and stability in strong acid, as well as fast metab…
View article: ProtTeX: Structure-In-Context Reasoning and Editing of Proteins with Large Language Models
ProtTeX: Structure-In-Context Reasoning and Editing of Proteins with Large Language Models Open
Large language models have made remarkable progress in the field of molecular science, particularly in understanding and generating functional small molecules. This success is largely attributed to the effectiveness of molecular tokenizati…
View article: Role of Mushroom Polysaccharides in Modulation of GI Homeostasis and Protection of GI Barrier
Role of Mushroom Polysaccharides in Modulation of GI Homeostasis and Protection of GI Barrier Open
Edible and medicinal mushroom polysaccharides (EMMPs) have been widely studied for their various biological activities. It has been shown that EMMPs could modulate microbiota in the large intestine and improve intestinal health. However, t…
View article: Extraction and purification of total flavonoids from Zanthoxylum planispinum Var. Dintanensis leaves and effect of altitude on total flavonoids content
Extraction and purification of total flavonoids from Zanthoxylum planispinum Var. Dintanensis leaves and effect of altitude on total flavonoids content Open
To investigate the impact of varying altitudes on the functional components of the leaves of Zanthoxylum planispinum var. Dintanensis, this research collected leaf samples from three different elevations: 610 m, 833 m, and 1083 m. Utilizin…
View article: A New Triangular Muscle Flap Esophagogastrostomy After Proximal Gastrectomy
A New Triangular Muscle Flap Esophagogastrostomy After Proximal Gastrectomy Open
This surgical technique can be safely performed and demonstrates excellent results in preventing gastroesophageal reflux. Further investigation through a multi-center clinical study is warranted to confirm its efficacy.
View article: Maternal Iron Levels and Association With Gestational Diabetes: A Systematic Review and Meta‐Analysis
Maternal Iron Levels and Association With Gestational Diabetes: A Systematic Review and Meta‐Analysis Open
Background: This systematic review aimed to assess the association of iron level with gestational diabetes mellitus (GDM) risk. Methods: The relevant articles published between January 1, 1995 and January 17, 2023 were identified through a…
View article: A fuzzy decentralized algorithm for high-rise buildings subjected to seismic excitations
A fuzzy decentralized algorithm for high-rise buildings subjected to seismic excitations Open
By the reason that mathematical analysis is not feasible for practical control of buildings, decentralized control (DC) and fuzzy control (FC) technologies were introduced to optimize the control problem of high-rise building (HRB) structu…
View article: Effects of the first frozen-thawed embryo transfer time on pregnancy outcomes after progestin primed ovarian stimulation regimen
Effects of the first frozen-thawed embryo transfer time on pregnancy outcomes after progestin primed ovarian stimulation regimen Open
This was an original article, mainly explored the effects of the first frozen-thawed embryo transfer (FET) time on pregnancy outcomes after progestin primed ovarian stimulation (PPOS) regimen. Our study implemented a retrospective analysis…
View article: Advancements in imaging of head and neck squamous cell carcinoma: A comprehensive review.
Advancements in imaging of head and neck squamous cell carcinoma: A comprehensive review. Open
As a prevalent malignancy with substantial incidence and mortality worldwide, head and neck squamous cell carcinoma (HNSCC) originates from multiple locations of different tissues, which level up the difficulty and complexity of the cancer…