Vasopressin
View article: Accumulation of prosaposin and progranulin around the subfornical organ induces polydipsia in SAP-D-deficient mice
Accumulation of prosaposin and progranulin around the subfornical organ induces polydipsia in SAP-D-deficient mice Open
View article: datasciencebioinformatics/preprocessing_scRNA_scATAC: A multiome analysis of sn-RNA and sn-ATAC of hypothalamus cells.
datasciencebioinformatics/preprocessing_scRNA_scATAC: A multiome analysis of sn-RNA and sn-ATAC of hypothalamus cells. Open
Two hypotlamus samples from mouse [1] were used as test data, each contaning both RNA and ATAC. Neuronal sub-poppulations were investigated for magnocellular population using markers Oxt, Avp and Caprin2. Interesting, clusters 9 and 10 sho…
View article: datasciencebioinformatics/preprocessing_scRNA_scATAC: A multiome analysis of sn-RNA and sn-ATAC of hypothalamus cells.
datasciencebioinformatics/preprocessing_scRNA_scATAC: A multiome analysis of sn-RNA and sn-ATAC of hypothalamus cells. Open
Two hypotlamus samples from mouse [1] were used as test data, each contaning both RNA and ATAC. Neuronal sub-poppulations were investigated for magnocellular population using markers Oxt, Avp and Caprin2. Interesting, clusters 9 and 10 sho…
View article: Hormonal and Osmoregulatory Responses in Intraoperative High-Volume Diuresis During Off-Pump Coronary Artery Bypass Grafting: An Exploratory Cohort Study
Hormonal and Osmoregulatory Responses in Intraoperative High-Volume Diuresis During Off-Pump Coronary Artery Bypass Grafting: An Exploratory Cohort Study Open
Background: Intraoperative high-volume diuresis is a frequent but underrecognized complication in cardiac surgery, potentially leading to hypovolemia, electrolyte imbalances, and hemodynamic instability. Its mechanisms remain poorly define…
View article: An interneuronal CRH and CRHBP circuit stabilizes birdsong performance
An interneuronal CRH and CRHBP circuit stabilizes birdsong performance Open
The performance of skilled behaviors requires a balance between consistency and adaptability. Although the neural mechanisms that regulate this balance have been extensively studied at systems and physiological levels, relatively little is…
View article: An interneuronal CRH and CRHBP circuit stabilizes birdsong performance
An interneuronal CRH and CRHBP circuit stabilizes birdsong performance Open
The performance of skilled behaviors requires a balance between consistency and adaptability. Although the neural mechanisms that regulate this balance have been extensively studied at systems and physiological levels, relatively little is…
View article: Oxytocin as a Survival System The Oxytocin - Dopamine Survival Axis and the Ferfers Safety -Gate Model
Oxytocin as a Survival System The Oxytocin - Dopamine Survival Axis and the Ferfers Safety -Gate Model Open
Oxytocin is framed here not as a marker of affection, but as the core neuroendocrine state of Rest-and-Connect through which organisms secure regulation, integration and developmental viability. Dopamine functions as the complementary Act-…
View article: Oxytocin as a Survival System The Oxytocin - Dopamine Survival Axis and the Ferfers Safety -Gate Model
Oxytocin as a Survival System The Oxytocin - Dopamine Survival Axis and the Ferfers Safety -Gate Model Open
Oxytocin is framed here not as a marker of affection, but as the core neuroendocrine state of Rest-and-Connect through which organisms secure regulation, integration and developmental viability. Dopamine functions as the com…
View article: Hypovolemia Evokes Conserved Inverse Neurovascular Coupling in the Supraoptic Nucleus Independent of Heart Failure
Hypovolemia Evokes Conserved Inverse Neurovascular Coupling in the Supraoptic Nucleus Independent of Heart Failure Open
Vasopressin (AVP) neurons in the hypothalamic supraoptic nucleus (SON) are activated by systemic challenges that threaten fluid balance. Beyond their classical activity-dependent release of their neuropeptide cargo into the systemic circul…
View article: Comparison of the Effects of Carbetocin and Oxytocin Injections in the Prevention of Postpartum Hemorrhage
Comparison of the Effects of Carbetocin and Oxytocin Injections in the Prevention of Postpartum Hemorrhage Open
View article: Hydration Responses to Pre-Exercise Sodium Hyperhydration at Rest and During Cycling in the Heat and Across Menstrual Cycle Phases
Hydration Responses to Pre-Exercise Sodium Hyperhydration at Rest and During Cycling in the Heat and Across Menstrual Cycle Phases Open
Purpose: This study examined hydration responses to sodium hyperhydration in female athletes at rest and during cycling across the early follicular and mid-luteal phases of the menstrual cycle. Methods: Twelve cyclists/triathletes consumed…
View article: Exploring vasopressin use in septic shock: a retrospective cohort study from Türkiye (VASCO-TURK)
Exploring vasopressin use in septic shock: a retrospective cohort study from Türkiye (VASCO-TURK) Open
View article: Heartfulness meditation alters neuroendocrine profiles: A randomized controlled trial on hormones of stress and well-being
Heartfulness meditation alters neuroendocrine profiles: A randomized controlled trial on hormones of stress and well-being Open
Background: Chronic stress disrupts the neuroendocrine system, leading to imbalances in neurotransmitters and stress hormones such as oxytocin, β endorphins and cortisol, contributing to mood disorders and poor emotional regulation. Comple…
View article: Treatment and outcome of a boy with lgG4-related hypophysitis caused by SARS-CoV-2 re-infection
Treatment and outcome of a boy with lgG4-related hypophysitis caused by SARS-CoV-2 re-infection Open
Rationale SARS-CoV-2 infection can directly and indirectly affect the nervous system, including the hypothalamus and pituitary, and potentially cause IgG4-related hypophysitis. Patient concerns A 4-year-old Chinese boy presented with argin…
View article: Dehydration Adaptation of the Adult Rat Modifies Brain Microtubule Electrical Activity of the Osmosensitive Supraoptic Nucleus
Dehydration Adaptation of the Adult Rat Modifies Brain Microtubule Electrical Activity of the Osmosensitive Supraoptic Nucleus Open
Brain microtubules (MTs) are important cytoskeletal structures in neurons that generate electrical oscillations in the frequency range of mammalian brain waves. However, the functional role of MT oscillations in the physiology of brain fun…
View article: Comparison of short-term and long-term renal function effects of vasopressin and norepinephrine in patients with septic shock: a systematic review and meta-analysis
Comparison of short-term and long-term renal function effects of vasopressin and norepinephrine in patients with septic shock: a systematic review and meta-analysis Open
Background Vasopressin and its derivatives, as second-line vasoactive agents, are increasingly being applied in the treatment of septic shock, but their effects on major organs, particularly the renal system, remain inadequately evaluated.…
View article: Arginine vasopressin deficiency after surgical ligation of an unruptured anterior communicating artery aneurysm – a case report and literature review
Arginine vasopressin deficiency after surgical ligation of an unruptured anterior communicating artery aneurysm – a case report and literature review Open
Introduction Plasma osmolality is maintained within a narrow range by secretion of arginine vasopressin (AVP). AVP deficiency (formerly known as central diabetes insipidus) is a rare complication of surgery in the hypothalamic and pituitar…
View article: Ovarian Hormones Moderate Systolic Hypertension in Female <i>Eln</i> Haploinsufficient Mice
Ovarian Hormones Moderate Systolic Hypertension in Female <i>Eln</i> Haploinsufficient Mice Open
Hypertension is a hallmark of cardiovascular abnormalities associated with Williams syndrome (WS), a rare genetic disorder involving microdeletion of genes on human chromosome 7, including the elastin gene ( ELN ). Heterozygous deletion of…
View article: Central Osmolality Sensing for Arginine Vasopressin Release Is Mediated by WNK1‐OSR1/SPAK‐Kv3.1 Cascade
Central Osmolality Sensing for Arginine Vasopressin Release Is Mediated by WNK1‐OSR1/SPAK‐Kv3.1 Cascade Open
Life depends on maintaining water homeostasis and internal osmolality constancy. In terrestrial animals, the release of the antidiuretic hormone arginine vasopressin (AVP) in response to variations of extracellular osmolality (tonicity) is…
View article: Effect of Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitors in the Management of Hyponatremia Associated With Syndrome of Inappropriate Antidiuresis
Effect of Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitors in the Management of Hyponatremia Associated With Syndrome of Inappropriate Antidiuresis Open
View article: Sex differences in central salt sensing in the human brain
Sex differences in central salt sensing in the human brain Open
In preclinical models, the organum vasculosum of the lamina terminalis (OVLT) and subfornical organ (SFO) sense changes in serum sodium chloride (NaCl) concentration and mediate NaCl-induced changes in sympathetic nerve activity, vasopress…
View article: The GLP-1 Analog Liraglutide Reduces Fever Through Sex-Dependent Neuroinflammatory Modulation
The GLP-1 Analog Liraglutide Reduces Fever Through Sex-Dependent Neuroinflammatory Modulation Open
Background/Objectives: Thermoregulation is essential for survival, with the hypothalamic preoptic area integrating peripheral signals to maintain core body temperature. While fever enhances immune responses, excessive hyperthermia causes c…
View article: Dysmenorrhea
Dysmenorrhea Open
Dysmenorrhea or painful menstruation, is among the most prevalent gynecological disorders affecting women of reproductive age and poses a significant global public health concern. It is classified into primary and secon…
View article: Catecholaminergic Adaptation to Extreme Military Stress: Norepinephrine and Dopamine Responses During and After SERE Training
Catecholaminergic Adaptation to Extreme Military Stress: Norepinephrine and Dopamine Responses During and After SERE Training Open
Catecholamines are fundamental mediators of the stress response, regulating arousal, vigilance, and adaptive behavior. However, their dynamics under extreme real-life conditions remain insufficiently explored. Survival, Evasion, Resistance…
View article: Epidemiology of acquired hypothalamic obesity following traumatic brain injury and nonspecific hypothalamic microinjury: A nationwide German claims data analysis
Epidemiology of acquired hypothalamic obesity following traumatic brain injury and nonspecific hypothalamic microinjury: A nationwide German claims data analysis Open
Acquired hypothalamic obesity (aHO) is characterized by rapid and persistent weight gain resulting from structural or functional damage to the hypothalamus, typically accompanied by neuroendocrine dysfunction. While aHO is well described i…
View article: Evaluation of antidepressant and sleep-promoting effects of cordycepin in a menopause-like stress model
Evaluation of antidepressant and sleep-promoting effects of cordycepin in a menopause-like stress model Open
The menopausal transition is often accompanied by mood disturbances and sleep disorders, exacerbated by estrogen deficiency and chronic stress. Although hormone replacement therapy (HRT) is effective, its use is limited by safety concerns,…
View article: Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress
Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress Open
Importance Close social relationships are linked to improved individual health and even longevity. These effects are hypothesized to be mediated through improved neuroendocrine and immune functioning, particularly in individuals who engage…
View article: Vasopressin Contributes to Respiratory and Cardiovascular Regulation in Spontaneously Hypertensive and Normotensive Rats
Vasopressin Contributes to Respiratory and Cardiovascular Regulation in Spontaneously Hypertensive and Normotensive Rats Open
Background: Vasopressin (AVP) and its V1a receptor (V1aR) are involved in the regulation of the cardiovascular system. Limited evidence suggests that AVP may also contribute to respiratory regulation. Arterial chemoreflex is the main refle…
View article: Efficacy of Targeted Vasopressin Injection at the Recto-Uterine Endometrioid Lesion during Laparoscopic Surgery for Deep Infiltrating Endometriosis
Efficacy of Targeted Vasopressin Injection at the Recto-Uterine Endometrioid Lesion during Laparoscopic Surgery for Deep Infiltrating Endometriosis Open
View article: Correction for Rigney et al., A vasopressin circuit that modulates mouse social investigation and anxiety-like behavior in a sex-specific manner
Correction for Rigney et al., A vasopressin circuit that modulates mouse social investigation and anxiety-like behavior in a sex-specific manner Open