Explanipedia

MANAGEMENT OF SKIN AGING AS A MODIFIABLE CONDITION THROUGH THE APPLICATION OF INNO TDS DNA PEPT HA FOR AN INTEGRATIVE APPROACH USING SONOPHORESIS. CADAVER ANALYSIS Open

Diaz de, Villabona Nancy, García, Guevara Victor, Velazco, Viloria Gladys · 2025

Abstract The facial region presents a complex anatomical stratigraphy that organizes its structures in distinct planes, facilitating the application of treatments while presenting textural variations tha…

Mussaenda recurvata Naiki, Tagane & Yahara Open

Huang Wei‐Yuan, TU Tie-yao, Nguyen Khang Sinh, Dang Van Son, Duan Ting-ting · 2025

Mussaenda recurvata Naiki, Tagane & Yahara, Phytotaxa 328: 167. 2017.Fig. 2≡ Mussaenda reflexisepala T. Chen & V. D. Nong, syn. nov., “Harvard Papers in Botany” 22: 127. 2017. Type. Vietnam. Ninh Thuan Province: Ninh Son Dist…

Ethylene modulates cell wall mechanics for root responses to compaction Open

Jiao Zhang, Zengyu Liu, Edward J. Farrar, Minhao Li, Hui Lu , et al. · 2025

Soil stresses affect crop yields and present global agricultural challenges 1 . Soil compaction triggers reduction in root length and radial expansion driven by the plant hormone ethylene 2 . Here we report how ethylene controls cell wall …

A Bioengineered Skin Organoid Platform for Modeling Human Skin Physiology and Cytotoxicity Open

Anastasiya Gorkun-Roeder, Naresh Mahajan, Gemma Nomdedeu‐Sancho, Adam Jorgensen, Kelsey Willson , et al. · 2025

Three-dimensional in vitro skin models are developed for studying skin physiology and drug toxicology. Most currently existing models are constructed through self-aggregation or layer-by-layer assembly of fibroblasts and keratinocytes only…

Synchrotron Micro‐X‐Ray Fluorescence Elemental Imaging Reveals Zinc Distribution in the Hyperaccumulator Sedum plumbizincicola (Crassulaceae) Open

Julien Jacquet, Ksenija Jakovljevic, Dennis Brueckner, Catherine Sirguey, Antony van der Ent , et al. · 2025

Sedum plumbizincicola is a zinc–cadmium (Zn–Cd) hyperaccumulator native to China with high potential for use in the phytoremediation of contaminated soils in temperate climates. This study aimed to determine the Zn accumulation and distrib…

Selected parameters of epidermal barrier in juveniles with type 1 diabetes correspond with the severity of diabetes – an observational study Open

Klaudia Bogusz‐Górna, Adriana Polanská, Aleksandra Dańczak-Pazdrowska, Ryszard Żaba, Piotr Fichna , et al. · 2025

Background Our study aimed to evaluate the epidermal barrier function in children with type 1 diabetes. To the author’s knowledge, no studies have been conducted on epidermal barrier parameters, including TEWL and measurement of epidermal …

Hyperoside Promotes Mitochondrial Autophagy Through the miR-361-5p/PI3K/Akt/mTOR Signaling Pathway, Thereby Improving UVB-Induced Photoaging Open

Danni Yang, Jiayi Le, Shuyun Xiao, Yulin Cui, Wanfang Zhu , et al. · 2025

Ultraviolet radiation B (UVB) radiation can induce oxidative stress, DNA damage, and inflammation, leading to skin wrinkling, impaired barrier function, and an increased risk of cancer. Addressing or preventing photoaging may provide a pro…

173 Phosphoproteomic profiling of the epidermis to enhance skin adaptation to the exposome Open

C. Lorion, A. Lopez-Gaydon, N. Bechetoille · 2025

212 Aged-related changes in epidermis metabolite composition Open

L. Mouret, I. Imbert, S. Pinacolo · 2025

205 Improvement of skin natural repairing mechanisms by targeting bound-ceramides synthesis by epidermis Open

S. Figueiredo, B. Fallou, E. Arbey, N Billoni, D. Bernard , et al. · 2025

169 TEDAR, a skin-specific long non-coding RNA, orchestrates the late epidermal differentiation program in the human epidermis Open

K. Das Mahapatra, O. Arslan, L. Luo, E. Kelemen, L. Pasquali , et al. · 2025

449 Long-Term Role of Hair Follicle Stem Cells in Epidermal Wound Healing Open

E Inamura, M. Watanabe, Hirano Y, G. Trajković, Kato S , et al. · 2025

Mapping cell dynamics in human ex vivo hair follicles suggests pulling mechanism of hair growth Open

Nicolas Tissot, Gaianne Genty, Roberto Santoprete, Frederic Baltenneck, Sébastien Thibaut , et al. · 2025

Homeostasis in continuously renewing organs like the gut, skin, and hair follicles relies on niche architecture and intricately orchestrated cellular dynamics, encompassing proliferation and migration. Here, we develop a 3D live imaging sy…

In Vitro and Ex Vivo Investigations on the Tolerance and Safety of a 3 kDa Sodium Hyaluronate for Topical Application Open

Morgane De Tollenaere, Anne Corriou, Anaïs Durduret, Moencopi Bernheim-Dennery, Tina Haupt , et al. · 2025

(1) Background: Low-molecular-weight hyaluronic acid displays moisturizing and anti-aging properties and reduces UV-induced inflammation when applied topically. A 3 kDa sodium hyaluronate oligosaccharide (Extra-Low HA) was designed, and st…

A skin-permeable polymer for non-invasive transdermal insulin delivery Open

Qiuyu Wei, Zhi He, Zifan Li, Zhuxian Zhou, Ying Piao , et al. · 2025

Non-invasive skin permeation is widely used for convenient transdermal delivery of small-molecule therapeutics (less than 500 Da) with appropriate hydrophobicities 1 . However, it has long been deemed infeasible for large molecules—particu…

MANAGEMENT OF SKIN AGING AS A MODIFIABLE CONDITION THROUGH THE APPLICATION OF INNO TDS DNA PEPT HA FOR AN INTEGRATIVE APPROACH USING SONOPHORESIS. CADAVER ANALYSIS Open

Diaz de, Villabona Nancy, García, Guevara Victor, Velazco, Viloria Gladys · 2025

The facial region presents a complex anatomical stratigraphy that organizes its structures in distinct planes, facilitating the application of treatments while presenting textural variations that require precise anatomical understanding. S…

The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation Open

Xue Yang, Feng He, Vanessa Lopez-Pajares, Douglas F Porter, Krassimira Garbett , et al. · 2025

Homeostasis relies on signaling networks controlled by cell membrane receptors. Although G-protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors, their specific roles in the epidermis are not fully understood.…

The Anti-Inflammatory and Skin Barrier Function Recovery Effects of Carica papaya Peel in Mice with Contact Dermatitis Open

Seon-ah Park, Kyoungmin Sun, Yeo-Jin Kim, Hyorhan Son, Jimi Lee , et al. · 2025

With growing concerns over the safety of synthetic substances, the development of plant-derived alternatives with minimal adverse effects has gained significant attention. Carica papaya L. peel contains a rich profile of bioactive compound…

Pharmacognostical Characterization and Phytochemical Profiling of Canna Indica L. (Cannaceae) Open

Megavarthini R.1*, Maheswari V.2, Ravikkumar V. R.3 · 2025

Adulteration or substitution of lower-quality herbal components frequently reduces their medicinal effectiveness and safety. Thus, establishing pharmacognostical and phytochemical criteria is critical for ensuring the legitimacy and …

Fermented rice bran extract delays skin aging by increasing the synthesis of collagen and elastin Open

Xin Yan, Meiqing Yang, Xuyi Cai, Yiwei Shen, Ruihan Jiang , et al. · 2025

Background Rice bran is the outer layer of rice grains ( Oryza sativa ). Due to its rich bioactive components, it has long been used in cosmetics. However, the mechanism by which it delays skin aging remains unclear. Methods In this study,…

Papular acantholytic dyskeratosis of the genitocrural area with positive direct immunofluorescence in a man affected by lichen sclerosus et atrophicus: a clinicopathological challenge Open

Diana Sacchi, Viviana Lora, Alessandra Latini, Monia Di Prete, Carlo Cota · 2025

Dear Editor, Papular acantholytic dyskeratosis (PAD) is a rare, sporadic, persistent disease of adulthood, localized to the genitocrural and anogenital regions. It was proposed as a new entity by Chorzelski et al. in 1984, based on the cas…

Single-cell spatial profiling identifies a mucosal-like epithelial signature in hidradenitis suppurativa tunnels Open

Adrianto, Indra · 2025

Hidradenitis Suppurativa (HS) is a chronic, relapsing inflammatory skin disease affecting 1-4% of the population. In advanced HS, tunnels (dermal sinus tracts) often form, perpetuating chronic inflammation. Early immunohistochemistry studi…

Single-cell spatial profiling identifies a mucosal-like epithelial signature in hidradenitis suppurativa tunnels Open

Adrianto, Indra · 2025

Hidradenitis Suppurativa (HS) is a chronic, relapsing inflammatory skin disease affecting 1-4% of the population. In advanced HS, tunnels (dermal sinus tracts) often form, perpetuating chronic inflammation. Early immunohistochemistry studi…

The role of PKC subtype-specific signaling in the regulation of adhesion in human keratinocytes and skin in pemphigus Open

Thomas Schmitt, Julia Haneberg, Desalegn Egu, Carla Sebastià Morón, Enno Schmidt , et al. · 2025

Aim Autoantibodies, in the blistering skin disease pemphigus primarily target desmosomal cadherins and cause loss of keratinocyte adhesion and epidermal blistering via signaling events. Pemphigus vulgaris is associated with autoantibodies …

MORPHO-ANATOMICAL STUDIES OF GREY MANGROVE (AVICENNIA MARINA) LEAF LOCATED IN INTER-TIDAL ZONE SANDSPIT BACKWATER, PAKISTAN Open

Kanwal Nazim, Achyut Tiwari, Sunanda Kodikara, Moinuddin Ahmed, Kanwal Nazim , et al. · 2025

Marine plants show a wide range of morphological and anatomical features under saline conditions. Avicennia marina (Forsk.) Vierh. is the dominant mangrove species and has been extensively studied, but the anatomical structures especially …

Sonic hedgehog signaling promotes basal epidermal fibrillin 3 expression for zebrafish fin ray branching Open

Samuel G Horst, Gabriel A. Yette, Astra L. Henner, Scott Stewart, Kryn Stankunas , et al. · 2025

Zebrafish robustly regenerate amputated fins, including restoring branched bony ray skeletons. During fin outgrowth, sonic hedgehog a ( shha )-expressing basal epidermal cells (bEps) signal to themselves and adjacent progenitor osteoblasts…

RNA-seq of scarab beetles under high- or low-nutrient Open

Cuicui Qi, Yonggang Hu · 2025

This study investigates the evolutionary mechanisms of horn plasticity through transcriptomic analysis of the postero-dorsal head epidermis in three Onthophagus species (O. rectecornutus, O. sagittarius, O. bivertex). Larvae were reared un…

Induction of Epidermal Pigmentation in ICR Mice through Weekly Sunlight Exposure: A Pilot Experimental Study Open

Asiyah Nanda Che Azit, Afiqah Nuwaira Ahmad Yasir, Humaira Fatini Mohd Faisal, Siti Syairah Mohd Mutalip, Yuslina Zakaria , et al. · 2025

Introduction. One reason for hyperpigmentation is elevated melanin deposition in the epidermis.Studies on hyperpigmentation are being increasingly reported, and one of the challenges of studying hyperpigmentation is to induce a large numbe…

Acridocarpus (Acridocarpus) Open

de Almeida, Rafael F., Rasambo, Sedera Norotiana, Elliott, Kelda, Pellegrini, Marco O. O., Rakotonirina, Nivohenintsoa , et al. · 2025

1.Acridocarpus subg. Acridocarpus(Niedenzu 1921: 17) Fig. 4 Acridocarpus subg. Acridocarpus sect. Acridocarpus (Niedenzu 1921: 17) Acridocarpus subg. Acridocarpus sect. Diacra Nied. (Niedenzu 1921: 17) Type species Acridocarpus plagiopteru…

Acridocarpus (Madagascariensis) R. F. Almeida 2025, stat. nov. Open

de Almeida, Rafael F., Rasambo, Sedera Norotiana, Elliott, Kelda, Pellegrini, Marco O. O., Rakotonirina, Nivohenintsoa , et al. · 2025

3.Acridocarpus subg. Madagascariensis(Arènes) R. F. Almeida stat. nov. Fig. 6 Acridocarpus subg. Anophyllaris sect. Micranthera subsect. Madagascariensis Arènes (Arènes 1945: 62) Acridocarpus subg. Anophyllaris sect. Micranthera Nied. (Nie…

Epidermis (zoology)