Red blood cell
View article: Assessment of Pharmacological Activity of Anthocephalus cadamba Bark Extract on Phenylhydrazine-Induced Anemia
Assessment of Pharmacological Activity of Anthocephalus cadamba Bark Extract on Phenylhydrazine-Induced Anemia Open
Anemia remains one of the most prevalent hematological disorders globally and continues to pose a serious health concern, particularly in developing countries where nutritional deficiencies, infections, and hemolytic conditions are widespr…
View article: Assessment of Pharmacological Activity of Anthocephalus cadamba Bark Extract on Phenylhydrazine-Induced Anemia
Assessment of Pharmacological Activity of Anthocephalus cadamba Bark Extract on Phenylhydrazine-Induced Anemia Open
Anemia remains one of the most prevalent hematological disorders globally and continues to pose a serious health concern, particularly in developing countries where nutritional deficiencies, infections, and hemolytic conditions are widespr…
View article: Prpf4 sequentially regulates the expansion and maturation of erythrocyte through distinct mechanisms
Prpf4 sequentially regulates the expansion and maturation of erythrocyte through distinct mechanisms Open
The proliferation of early erythrocyte and the subsequent maturation are critical events during erythropoiesis, while how these two independent but interconnected processes are efficiently orchestrated during erythropoiesis is largely unkn…
View article: Oxidative Stress and Haematological Alterations in Wistar Rats Exposed to Polluted and Phytoremediated Ubeji River Water
Oxidative Stress and Haematological Alterations in Wistar Rats Exposed to Polluted and Phytoremediated Ubeji River Water Open
This study aimed to evaluate the haematological, biochemical, and antioxidant alterations resulting from graded exposure to polluted river water and to determine the potential health risks associated with such contamination, while also ass…
View article: EFFECTS OF FERULA TADSHIKORUM RESIN EXTRACT ON CELL VOLUME REGULATION IN RAT THYMOCYTES AND MEMBRANE INTEGRITY OF HUMAN ERYTHROCYTES
EFFECTS OF FERULA TADSHIKORUM RESIN EXTRACT ON CELL VOLUME REGULATION IN RAT THYMOCYTES AND MEMBRANE INTEGRITY OF HUMAN ERYTHROCYTES Open
The study presents data on the ethanol extract of Ferula tadshikorum resin. It was found that the extract inhibits the cell volume regulation system in thymocyte cells and induces the formation of pores with a radius of ~3.3 nm in the eryt…
View article: Oxidative Stress and Haematological Alterations in Wistar Rats Exposed to Polluted and Phytoremediated Ubeji River Water
Oxidative Stress and Haematological Alterations in Wistar Rats Exposed to Polluted and Phytoremediated Ubeji River Water Open
This study aimed to evaluate the haematological, biochemical, and antioxidant alterations resulting from graded exposure to polluted river water and to determine the potential health risks associated with such contamination, while also ass…
View article: EFFECTS OF FERULA TADSHIKORUM RESIN EXTRACT ON CELL VOLUME REGULATION IN RAT THYMOCYTES AND MEMBRANE INTEGRITY OF HUMAN ERYTHROCYTES
EFFECTS OF FERULA TADSHIKORUM RESIN EXTRACT ON CELL VOLUME REGULATION IN RAT THYMOCYTES AND MEMBRANE INTEGRITY OF HUMAN ERYTHROCYTES Open
The study presents data on the ethanol extract of Ferula tadshikorum resin. It was found that the extract inhibits the cell volume regulation system in thymocyte cells and induces the formation of pores with a radius of ~3.3 nm in the eryt…
View article: Impact of red blood cell distribution width on response to HIF-PH inhibitor in improving anemia and clinical outcomes in patients with chronic kidney disease
Impact of red blood cell distribution width on response to HIF-PH inhibitor in improving anemia and clinical outcomes in patients with chronic kidney disease Open
View article: Red blood cell to platelet ratio and its trajectory as prognostic factors for patients with gastrointestinal tract perforation and abdominal sepsis
Red blood cell to platelet ratio and its trajectory as prognostic factors for patients with gastrointestinal tract perforation and abdominal sepsis Open
Background Sepsis after emergency gastrointestinal perforation surgery increases costs and hospital stay. Early diagnosis and management are vital. This study assesses the prognostic value of the red blood cell to platelet ratio (RPR) in t…
View article: Antioxidant and Erythroprotective Effects of C-Phycocyanin from the Cyanobacterium <em>Spirulina</em> sp. in Attenuating Oxidative Stress Induced by Peroxyl Radicals
Antioxidant and Erythroprotective Effects of C-Phycocyanin from the Cyanobacterium <em>Spirulina</em> sp. in Attenuating Oxidative Stress Induced by Peroxyl Radicals Open
Blood groups in the ABO system and the RhD factor is of great clinical importance, as it is related to susceptibility to various diseases caused by oxidative stress. The use of antioxidants such as C-phycocyanin (a phycobiliprotein) could …
View article: The red blood cell-platelet ratio affects prognosis.
The red blood cell-platelet ratio affects prognosis. Open
(A) Survival curve analysis of the red blood cell-platelet ratio on the first day in the ICU during hospitalization. (B) Survival curve analysis of the red blood cell-platelet ratio on the second day in the ICU during hospita…
View article: Comparative Assessment of the Antioxidant Efficacy of Trigonella foenum-graecum and Hibiscus rosa-sinensis in Reversing Phenylhydrazine-Mediated Hemolytic Anemia in Mus Musculus
Comparative Assessment of the Antioxidant Efficacy of Trigonella foenum-graecum and Hibiscus rosa-sinensis in Reversing Phenylhydrazine-Mediated Hemolytic Anemia in Mus Musculus Open
Investigation of antioxidant properties of Trigonella foenum-graecum (fenugreek) seed and Hibiscus rosa-sinensis (China rose) bark extracts in phenylhydrazine (PHZ)-induced anaemia models in mice. Ethanol extracts of both plant materials w…
View article: Red blood cell-platelet ratio and HR-restriction cube diagram during hospitalization.
Red blood cell-platelet ratio and HR-restriction cube diagram during hospitalization. Open
(A) Relationship between red blood cell-platelet ratio and HR during hospitalization on the first day in the ICU. (B) Relationship between red blood cell-platelet ratio and HR during hospitalization on the first day in the IC…
View article: Impact of red blood cell-platelet ratio trajectories on prognosis and clinical outcomes in the first four days before ICU admission in the training set.
Impact of red blood cell-platelet ratio trajectories on prognosis and clinical outcomes in the first four days before ICU admission in the training set. Open
(A) Impact trajectory categories of red blood cell-platelet ratio in the first four days before ICU admission in the training set. (B) Differences in fibrinogen levels between different impact trajectory categories of red blo…
View article: Impact of red blood cell-platelet ratio trajectories in the first four days before ICU admission on prognosis and clinical outcomes in the validation set.
Impact of red blood cell-platelet ratio trajectories in the first four days before ICU admission on prognosis and clinical outcomes in the validation set. Open
(A) Trajectory categories of the impact of red blood cell-platelet ratio in the first four days before ICU admission in the validation set. (B) Differences in fibrinogen levels between different trajectory categories of the i…
View article: Table 1_Monocyte–red blood cell crosstalk supports clearance and heme metabolism in sickle cell anemia.docx
Table 1_Monocyte–red blood cell crosstalk supports clearance and heme metabolism in sickle cell anemia.docx Open
Background Monocytes can interact with erythroid cells and contribute to macrophage pools under anemic stress, thereby supporting the erythropoietic niche. In sickle cell anemia (SCA), extensive hemolysis and ineffective erythropoiesis may…
View article: Single-nucleus RNA-seq of archived PAXgene whole blood samples
Single-nucleus RNA-seq of archived PAXgene whole blood samples Open
Summary - No method has been developed for single-cell analysis of the large repositories of preserved whole blood samples stored in PAXgene Blood RNA tubes. To address this gap, two nuclei isolation techniques for single-nucleus RNA seque…
View article: Single-nucleus RNA-seq of archived PAXgene whole blood samples
Single-nucleus RNA-seq of archived PAXgene whole blood samples Open
Summary - No method has been developed for single-cell analysis of the large repositories of preserved whole blood samples stored in PAXgene Blood RNA tubes. To address this gap, two nuclei isolation techniques for single-nucleus RNA seque…
View article: Prognostic Impact of Red Blood Cell-Platelet Ratio Trajectory Categories after PSM.
Prognostic Impact of Red Blood Cell-Platelet Ratio Trajectory Categories after PSM. Open
(A) Covariate imbalance plot of propensity score matching. (B) Survival curve analysis during hospitalization based on different red blood cell-platelet ratio trajectory categories. (C) Survival curve analysis during I…
View article: Supplementary file 1_Association between red blood cell distribution width coefficient of variation and post-treatment bilirubin decline velocity in neonatal hyperbilirubinemia.doc
Supplementary file 1_Association between red blood cell distribution width coefficient of variation and post-treatment bilirubin decline velocity in neonatal hyperbilirubinemia.doc Open
Background Red blood cell distribution width coefficient of variation (RDW-CV) reflects erythrocyte heterogeneity, but its correlation with posttreatment bilirubin kinetics in neonatal hyperbilirubinemia (NHB) remains underexplored. Method…
View article: Indirect hemagglutination assay.
Indirect hemagglutination assay. Open
Created in BioRender. Gassiep, I. (2025) https://BioRender.com/xbq39lt. B. pseudomallei isolates are combined to form a crude, nonstandardised, antigen rich lysate. This lysate is used to sensitise sheep red blood cells (RBCs) with …
View article: Effect of Lactoferrin on blood parameters and lipid levels in anemic rats
Effect of Lactoferrin on blood parameters and lipid levels in anemic rats Open
The study aimed to investigate the effect of Lactoferrin on blood picture parameters and lipid levels in rats suffering from anemia after 28 days of the experiment. the results showed that in the group with anemia there was a decreased in …
View article: Changes in Hematobiochemical Parameters with Aging in Afshari Sheep
Changes in Hematobiochemical Parameters with Aging in Afshari Sheep Open
The Afshari sheep, valued for their adaptability and productivity, are vital to Iran's livestock sector, especially in the Mashhad region. This study examines the effects of age on biochemical and hematological parameters in eighteen clini…
View article: Correlation of Red Cell distribution width and Neutrophil to Lymphocyte ratio with Disease activity in Rheumatoid Arthritis
Correlation of Red Cell distribution width and Neutrophil to Lymphocyte ratio with Disease activity in Rheumatoid Arthritis Open
Background and objectives: The study investigated the relationship between red cell distribution width and neutrophil-to-lymphocyte ratio with disease activity in rheumatoid arthritis. These markers provide insights into inflammation and i…
View article: Preclinical assessment of the acute hematological safety of an antimicrobial ethanolic phytoextract from Combretum racemosum in Wistar rats
Preclinical assessment of the acute hematological safety of an antimicrobial ethanolic phytoextract from Combretum racemosum in Wistar rats Open
Many ethanolic phytoextracts exhibit promising antimicrobial performance but may also display toxic effects, particularly on blood erythrocytes, potentially leading to acute hemolytic anemia. Therefore, it is essential to verify their safe…
View article: Preclinical assessment of the acute hematological safety of an antimicrobial ethanolic phytoextract from Combretum racemosum in Wistar rats
Preclinical assessment of the acute hematological safety of an antimicrobial ethanolic phytoextract from Combretum racemosum in Wistar rats Open
Many ethanolic phytoextracts exhibit promising antimicrobial performance but may also display toxic effects, particularly on blood erythrocytes, potentially leading to acute hemolytic anemia. Therefore, it is essential to verify their safe…
View article: Seeing WhatSticks: Anchoring Capabilities of Moietiesfor Use in Cell-Conveyed Therapeutics
Seeing WhatSticks: Anchoring Capabilities of Moietiesfor Use in Cell-Conveyed Therapeutics Open
Red blood cells (RBCs) have been employed to convey and deliver a variety of therapeutic agents, from small molecules to proteins. The therapeutics are typically installed within the RBC interior via a pore-forming process that results in …
View article: CORPUSCULAR ELEMENTS OF BLOOD: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE
CORPUSCULAR ELEMENTS OF BLOOD: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE Open
The corpuscular elements of blood, also known as formed elements, include red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). These cellular components perform vital functions essential for maintai…
View article: CORPUSCULAR ELEMENTS OF BLOOD: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE
CORPUSCULAR ELEMENTS OF BLOOD: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE Open
The corpuscular elements of blood, also known as formed elements, include red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). These cellular components perform vital functions essential for maintai…
View article: Hemoglobin to red blood cell distribution width ratio inversely associated with heart failure in NHANES 2011–2018
Hemoglobin to red blood cell distribution width ratio inversely associated with heart failure in NHANES 2011–2018 Open
Hemoglobin-to-red cell distribution width ratio (HRR), a composite index reflecting both oxygen-carrying capacity and erythrocyte heterogeneity, has recently been proposed as a prognostic biomarker in cardiovascular disease. However, its a…